| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil (mesylate) perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belumosudil (mesylate)_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | 0.449235 |
| LMO7 | LIM domain 7 | 0.139509 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0756618 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0692504 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0671898 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0618398 |
| TMC5 | transmembrane channel-like 5 | 0.0580106 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0541719 |
| RUNX1 | runt-related transcription factor 1 | 0.0528736 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0492286 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0461143 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0456663 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0454321 |
| MCU | mitochondrial calcium uniporter | 0.0421047 |
| POF1B | premature ovarian failure, 1B | 0.0399869 |
| CDK6 | cyclin-dependent kinase 6 | 0.0384637 |
| SIK3 | SIK family kinase 3 | 0.0373982 |
| MYO1E | myosin IE | 0.0372231 |
| COBL | cordon-bleu WH2 repeat protein | 0.03681 |
| EMP1 | epithelial membrane protein 1 | 0.0360198 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0357081 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | 0.0343769 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.034355 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0343153 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.033924 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.033305 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.032799 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0323645 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0320155 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0317655 |
| EXOC4 | exocyst complex component 4 | 0.031154 |
| EFNA5 | ephrin-A5 | 0.0299493 |
| INTS6 | integrator complex subunit 6 | 0.0296296 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.029613 |
| RPL4 | ribosomal protein L4 | 0.028741 |
| SPATA13 | spermatogenesis associated 13 | 0.0283324 |
| FRMD5 | FERM domain containing 5 | 0.0281822 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0279172 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0274867 |
| GDA | guanine deaminase | 0.0266476 |
| SHROOM3 | shroom family member 3 | 0.0266443 |
| EHBP1 | EH domain binding protein 1 | 0.0261731 |
| ATXN1 | ataxin 1 | 0.0253971 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0251442 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0245284 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0243166 |
| CNKSR3 | CNKSR family member 3 | 0.0240594 |
| TCF12 | transcription factor 12 | 0.0240056 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0239879 |
| ANXA1 | annexin A1 | 0.0238997 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0237633 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0236836 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0235652 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0234753 |
| GOLGB1 | golgin B1 | 0.023127 |
| SERINC5 | serine incorporator 5 | 0.0225742 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 0.0225647 |
| ETV6 | ets variant 6 | 0.0221742 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0221414 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0220545 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0214999 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0212871 |
| HDAC9 | histone deacetylase 9 | 0.0212423 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0210381 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0206236 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0201652 |
| AOPEP | aminopeptidase O (putative) | 0.0201384 |
| SMAD3 | SMAD family member 3 | 0.020074 |
| FNIP1 | folliculin interacting protein 1 | 0.0196995 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0195109 |
| UBC | ubiquitin C | 0.0193735 |
| CUX1 | cut-like homeobox 1 | 0.0192144 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.019109 |
| FAAH2 | fatty acid amide hydrolase 2 | 0.0190507 |
| DST | dystonin | 0.0190125 |
| MYO1D | myosin ID | 0.0190039 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0189896 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0189699 |
| CMIP | c-Maf inducing protein | 0.0187498 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0185822 |
| MYOF | myoferlin | 0.0185398 |
| CDK13 | cyclin-dependent kinase 13 | 0.0183822 |
| PMM2 | phosphomannomutase 2 | 0.0179431 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0179058 |
| SP100 | SP100 nuclear antigen | 0.0178573 |
| CD2AP | CD2-associated protein | 0.0175791 |
| TOM1L2 | target of myb1-like 2 (chicken) | 0.0174242 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0173075 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0172371 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0171367 |
| RASEF | RAS and EF-hand domain containing | 0.0171257 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0171222 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0166809 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0166181 |
| SEPTIN9 | septin 9 | 0.0164035 |
| RAD51B | RAD51 paralog B | 0.0163149 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0162947 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0162131 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0161868 |
| TNS3 | tensin 3 | 0.0161404 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.150077 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.123875 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.106767 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0893436 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0802512 |
| TMSB10 | thymosin beta 10 | -0.0738352 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0733616 |
| S100A6 | S100 calcium binding protein A6 | -0.0706647 |
| RPL35A | ribosomal protein L35a | -0.0600444 |
| B2M | beta-2-microglobulin | -0.0580086 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0549962 |
| POTEF | POTE ankyrin domain family, member F | -0.0536427 |
| FTL | ferritin, light polypeptide | -0.0519461 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0502524 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0477467 |
| KRT18 | keratin 18, type I | -0.0462735 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0459824 |
| ANLN | anillin, actin binding protein | -0.0457639 |
| HMGA1 | high mobility group AT-hook 1 | -0.0445426 |
| AGR2 | anterior gradient 2 | -0.0444836 |
| S100P | S100 calcium binding protein P | -0.0444668 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0440384 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0432176 |
| KRT19 | keratin 19, type I | -0.043114 |
| HYOU1 | hypoxia up-regulated 1 | -0.043086 |
| NPSR1 | neuropeptide S receptor 1 | -0.0424498 |
| S100A10 | S100 calcium binding protein A10 | -0.04236 |
| CLDN7 | claudin 7 | -0.0402433 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0402121 |
| LYZ | lysozyme | -0.040015 |
| CALR | calreticulin | -0.039988 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0381286 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0379763 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0367405 |
| AREG | amphiregulin | -0.03646 |
| PGK1 | phosphoglycerate kinase 1 | -0.0354514 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0349627 |
| GOLGA4 | golgin A4 | -0.034779 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0346774 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0345262 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0341862 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0340468 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.033778 |
| XPO1 | exportin 1 | -0.0335346 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0335234 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0319081 |
| PTMA | prothymosin, alpha | -0.0316814 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0310429 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0309793 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0309604 |
| RPS19 | ribosomal protein S19 | -0.0307373 |
| RPL23 | ribosomal protein L23 | -0.0305881 |
| MUC17 | mucin 17, cell surface associated | -0.0297455 |
| ITGB4 | integrin, beta 4 | -0.0285888 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0283635 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0280488 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0277583 |
| WDR45B | WD repeat domain 45B | -0.0274576 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0272715 |
| PCBP2 | poly(rC) binding protein 2 | -0.0267684 |
| INSIG1 | insulin induced gene 1 | -0.0267415 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.026454 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0262747 |
| RPLP1 | ribosomal protein, large, P1 | -0.0261696 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0261334 |
| RTN4 | reticulon 4 | -0.0257398 |
| S100A9 | S100 calcium binding protein A9 | -0.0256886 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0253931 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0250544 |
| TES | testin LIM domain protein | -0.0247916 |
| HLA-A | major histocompatibility complex, class I, A | -0.0247899 |
| ACTG1 | actin gamma 1 | -0.024747 |
| MUC1 | mucin 1, cell surface associated | -0.0247251 |
| CBX3 | chromobox homolog 3 | -0.0247232 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.024684 |
| JUP | junction plakoglobin | -0.024683 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0246554 |
| KLK10 | kallikrein-related peptidase 10 | -0.0245055 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0244909 |
| PFN1 | profilin 1 | -0.0243977 |
| DEK | DEK proto-oncogene | -0.0242256 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0241402 |
| NDRG1 | N-myc downstream regulated 1 | -0.0240765 |
| PKM | pyruvate kinase, muscle | -0.0239022 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0237099 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0231411 |
| NUP58 | nucleoporin 58 | -0.0230943 |
| WASF2 | WAS protein family, member 2 | -0.0230363 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0229866 |
| RPL19 | ribosomal protein L19 | -0.022846 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0228315 |
| ARF4 | ADP-ribosylation factor 4 | -0.022755 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0226292 |
| AFTPH | aftiphilin | -0.0225739 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0225414 |
| KRT8 | keratin 8, type II | -0.0224663 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0221277 |
| PERP | PERP, TP53 apoptosis effector | -0.0220026 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0217843 |
| SERP1 | stress-associated endoplasmic reticulum protein 1 | -0.021623 |
