| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil (mesylate) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Belumosudil (mesylate)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EFNA5 | ephrin-A5 | 0.136599 |
| RPL4 | ribosomal protein L4 | 0.0744372 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.066799 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.063882 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0587749 |
| DTNA | dystrobrevin, alpha | 0.0583244 |
| HDAC9 | histone deacetylase 9 | 0.0578454 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0489186 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0467252 |
| INTS6 | integrator complex subunit 6 | 0.0444906 |
| NAV1 | neuron navigator 1 | 0.0439501 |
| SAMD3 | sterile alpha motif domain containing 3 | 0.0437819 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0401097 |
| AHNAK | AHNAK nucleoprotein | 0.0367065 |
| PRKCE | protein kinase C, epsilon | 0.0349136 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.0348802 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0347331 |
| AEBP2 | AE binding protein 2 | 0.0343873 |
| HMGA2 | high mobility group AT-hook 2 | 0.0340699 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0327245 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0314095 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.031348 |
| RPS12 | ribosomal protein S12 | 0.0311982 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0302065 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0299839 |
| RPL13A | ribosomal protein L13a | 0.0290071 |
| ASPH | aspartate beta-hydroxylase | 0.0286272 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0269406 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0261099 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0257877 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0254047 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0249495 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0240317 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0237804 |
| USP34 | ubiquitin specific peptidase 34 | 0.0234009 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0230525 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0225085 |
| ANO6 | anoctamin 6 | 0.0224476 |
| UBC | ubiquitin C | 0.0215882 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0212749 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.020756 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0201372 |
| ARFGEF3 | ARFGEF family member 3 | 0.0198883 |
| BPTF | bromodomain PHD finger transcription factor | 0.0197638 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0194618 |
| DOCK1 | dedicator of cytokinesis 1 | 0.019299 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.01927 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0192458 |
| MYO9A | myosin IXA | 0.0191553 |
| FNIP1 | folliculin interacting protein 1 | 0.0191124 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0190986 |
| GPHN | gephyrin | 0.0185142 |
| ZNF804A | zinc finger protein 804A | 0.0183005 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0182538 |
| DST | dystonin | 0.0182097 |
| RPS8 | ribosomal protein S8 | 0.0182057 |
| NBEA | neurobeachin | 0.0181399 |
| RPS2 | ribosomal protein S2 | 0.0179205 |
| GOLGB1 | golgin B1 | 0.0178981 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0175668 |
| KIAA1328 | KIAA1328 | 0.0173473 |
| NAV3 | neuron navigator 3 | 0.0173351 |
| PRELID2 | PRELI domain containing 2 | 0.0172233 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0171372 |
| PHF3 | PHD finger protein 3 | 0.0171173 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0170698 |
| RPS3 | ribosomal protein S3 | 0.0168521 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.016837 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.0167139 |
| ATXN1 | ataxin 1 | 0.0166931 |
| GLIS3 | GLIS family zinc finger 3 | 0.0166124 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0166072 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0165297 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0160508 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0159424 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.015646 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0156073 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0154547 |
| PTCHD4 | patched domain containing 4 | 0.0151596 |
| TRIM44 | tripartite motif containing 44 | 0.0150089 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.014911 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0147416 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0141051 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0140491 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0138082 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.013719 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | 0.0137027 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0136952 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0136545 |
| H1-4 | H1.4 linker histone, cluster member | 0.0136078 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0136072 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0135992 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0135981 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0135377 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0134271 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | 0.0133093 |
| RUNX1 | runt-related transcription factor 1 | 0.0132218 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0130532 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0128892 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0128796 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.248823 |
| TMSB10 | thymosin beta 10 | -0.198114 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.183155 |
| PTMA | prothymosin, alpha | -0.1154 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.108733 |
| MT2A | metallothionein 2A | -0.0936938 |
| RPL35A | ribosomal protein L35a | -0.0732152 |
| RTN4 | reticulon 4 | -0.0698105 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0677964 |
| HMGA1 | high mobility group AT-hook 1 | -0.0609105 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0599466 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0572446 |
| RPS19 | ribosomal protein S19 | -0.0559339 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0558773 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0535067 |
| NUP58 | nucleoporin 58 | -0.0519772 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0501254 |
| YBX3 | Y box binding protein 3 | -0.0500677 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0485781 |
| TPM4 | tropomyosin 4 | -0.0471668 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0471042 |
| RPL23 | ribosomal protein L23 | -0.0464384 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0457429 |
| MMP12 | matrix metallopeptidase 12 | -0.0449987 |
| FN1 | fibronectin 1 | -0.044766 |
| ANXA2 | annexin A2 | -0.0447207 |
| RPLP1 | ribosomal protein, large, P1 | -0.0444248 |
| RPS6 | ribosomal protein S6 | -0.0432916 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0429438 |
| VCL | vinculin | -0.0426074 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0422352 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.041677 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0397052 |
| TXNRD1 | thioredoxin reductase 1 | -0.0395965 |
| RBM39 | RNA binding motif protein 39 | -0.0392161 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0381543 |
| FTL | ferritin, light polypeptide | -0.0376858 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0375124 |
| PCBP2 | poly(rC) binding protein 2 | -0.0364456 |
| SPAG9 | sperm associated antigen 9 | -0.0359825 |
| ZNF292 | zinc finger protein 292 | -0.0351706 |
| PKM | pyruvate kinase, muscle | -0.0350852 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0349584 |
| CDK17 | cyclin-dependent kinase 17 | -0.0341335 |
| CTSB | cathepsin B | -0.0340725 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0331421 |
| PGK1 | phosphoglycerate kinase 1 | -0.033083 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0330768 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0330599 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0327707 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0327684 |
| TPI1 | triosephosphate isomerase 1 | -0.0327665 |
| HAS2 | hyaluronan synthase 2 | -0.0327367 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0325327 |
| PFN1 | profilin 1 | -0.0325298 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.031777 |
| CD44 | CD44 molecule (Indian blood group) | -0.0316744 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0308539 |
| KISS1 | KiSS-1 metastasis-suppressor | -0.0307147 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0298919 |
| RPL8 | ribosomal protein L8 | -0.0297824 |
| SEPTIN7 | septin 7 | -0.0295398 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0294092 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0285179 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.028504 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0280801 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0280477 |
| CD109 | CD109 molecule | -0.0278084 |
| RNF145 | ring finger protein 145 | -0.0277945 |
| GNAS | GNAS complex locus | -0.0277731 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0276292 |
| POTEF | POTE ankyrin domain family, member F | -0.0274617 |
| FOSL1 | FOS-like antigen 1 | -0.0273966 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0273738 |
| WDR45B | WD repeat domain 45B | -0.0264103 |
| RPLP2 | ribosomal protein, large, P2 | -0.0264028 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0263171 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0262843 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0260348 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0258541 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0257851 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0257711 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0254734 |
| RLF | rearranged L-myc fusion | -0.025419 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0253226 |
| YBX1 | Y box binding protein 1 | -0.0252563 |
| QKI | QKI, KH domain containing, RNA binding | -0.0251027 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0251003 |
| KLF6 | Kruppel-like factor 6 | -0.0250034 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0249364 |
| RPS21 | ribosomal protein S21 | -0.0248689 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0247967 |
| CCNL1 | cyclin L1 | -0.0247809 |
| SETD5 | SET domain containing 5 | -0.0247278 |
| MATR3 | matrin 3 | -0.0243423 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0242909 |
| ZNF207 | zinc finger protein 207 | -0.0242473 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0240536 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0240378 |
| ACTN4 | actinin, alpha 4 | -0.023851 |
