| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil (mesylate) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Belumosudil (mesylate)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0710507 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.05881 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0566446 |
| H1-0 | H1.0 linker histone | 0.0486981 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0465739 |
| SDC4 | syndecan 4 | 0.046368 |
| RPS12 | ribosomal protein S12 | 0.0437654 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0424121 |
| UBC | ubiquitin C | 0.0424089 |
| RIGI | RNA sensor RIG-I | 0.0422563 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0358541 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0355401 |
| FMNL2 | formin-like 2 | 0.0351647 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0349973 |
| ADAR | adenosine deaminase, RNA-specific | 0.034596 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0338721 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0327629 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0327621 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0323309 |
| SP100 | SP100 nuclear antigen | 0.0320537 |
| KLF6 | Kruppel-like factor 6 | 0.0317026 |
| RUNX1 | runt-related transcription factor 1 | 0.0304725 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0304179 |
| HDAC9 | histone deacetylase 9 | 0.0282014 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0274671 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0272103 |
| TP63 | tumor protein p63 | 0.0267326 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0267097 |
| RPL4 | ribosomal protein L4 | 0.0264728 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0257013 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0255277 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0250673 |
| RPL13A | ribosomal protein L13a | 0.0241322 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0235315 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0227891 |
| TPM3 | tropomyosin 3 | 0.0220256 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0216699 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.021591 |
| ERBIN | erbb2 interacting protein | 0.0212007 |
| AHNAK | AHNAK nucleoprotein | 0.0210978 |
| RAD51B | RAD51 paralog B | 0.0210483 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0210262 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0209906 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0207601 |
| VMP1 | vacuole membrane protein 1 | 0.0206216 |
| TXNIP | thioredoxin interacting protein | 0.0205683 |
| PTK2 | protein tyrosine kinase 2 | 0.0204123 |
| GTF2I | general transcription factor IIi | 0.0200178 |
| ENO1 | enolase 1, (alpha) | 0.0198304 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0197309 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0195663 |
| XAF1 | XIAP associated factor 1 | 0.0193493 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0192997 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0192094 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0186303 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0183664 |
| NCKAP1 | NCK-associated protein 1 | 0.018324 |
| XPO1 | exportin 1 | 0.0182393 |
| ENAH | enabled homolog (Drosophila) | 0.0180934 |
| SMYD3 | SET and MYND domain containing 3 | 0.0179118 |
| THOC2 | THO complex 2 | 0.0178507 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.017768 |
| EREG | epiregulin | 0.017706 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.017659 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0174365 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0172805 |
| RPS18 | ribosomal protein S18 | 0.0171175 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0170917 |
| TOP1 | topoisomerase (DNA) I | 0.0168037 |
| BRD2 | bromodomain containing 2 | 0.016759 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0165737 |
| PHIP | pleckstrin homology domain interacting protein | 0.0165084 |
| CAPRIN2 | caprin family member 2 | 0.0164246 |
| QKI | QKI, KH domain containing, RNA binding | 0.0162234 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 | 0.0162227 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0161192 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0161089 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.015981 |
| RTN4 | reticulon 4 | 0.0159007 |
| DIAPH3 | diaphanous-related formin 3 | 0.0156771 |
| NF1 | neurofibromin 1 | 0.0155581 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0155315 |
| DENND5A | DENN/MADD domain containing 5A | 0.0155295 |
| RPS2 | ribosomal protein S2 | 0.0154754 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0154651 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0154313 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0153514 |
| NSD1 | nuclear receptor binding SET domain protein 1 | 0.0150994 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0150753 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0150125 |
| MT1X | metallothionein 1X | 0.0149052 |
| TRIM44 | tripartite motif containing 44 | 0.0147775 |
| USP24 | ubiquitin specific peptidase 24 | 0.0147561 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0147516 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0146394 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0145604 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0145302 |
| RLF | rearranged L-myc fusion | 0.014482 |
| SQSTM1 | sequestosome 1 | 0.0143597 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.014349 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.239684 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.160478 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.157268 |
| PTMA | prothymosin, alpha | -0.14883 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.124084 |
| TMSB10 | thymosin beta 10 | -0.116384 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.108064 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.104277 |
| CD44 | CD44 molecule (Indian blood group) | -0.0732309 |
| TMSB4X | thymosin beta 4, X-linked | -0.0723165 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0691526 |
| CANX | calnexin | -0.0616437 |
| CADM2 | cell adhesion molecule 2 | -0.0611815 |
| RPL35A | ribosomal protein L35a | -0.0603139 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0601201 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0563389 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0517945 |
| EFNA5 | ephrin-A5 | -0.049278 |
| HMGA1 | high mobility group AT-hook 1 | -0.0464136 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0453151 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0441036 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0422762 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0402594 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0398965 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0391979 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0388568 |
| TMEM123 | transmembrane protein 123 | -0.0381025 |
| LOXL2 | lysyl oxidase-like 2 | -0.0367358 |
| EHBP1 | EH domain binding protein 1 | -0.0366299 |
| MYOF | myoferlin | -0.036392 |
| DOCK11 | dedicator of cytokinesis 11 | -0.0362296 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0361798 |
| ACTG1 | actin gamma 1 | -0.035999 |
| SRGN | serglycin | -0.0327679 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0319746 |
| PGK1 | phosphoglycerate kinase 1 | -0.0316911 |
| VCL | vinculin | -0.0314514 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.031418 |
| HDLBP | high density lipoprotein binding protein | -0.0307379 |
| CALR | calreticulin | -0.0306404 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0306238 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0305349 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.028992 |
| EPHA4 | EPH receptor A4 | -0.0288212 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.02863 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0277876 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0277455 |
| FTL | ferritin, light polypeptide | -0.027405 |
| RPS8 | ribosomal protein S8 | -0.0273945 |
| POTEF | POTE ankyrin domain family, member F | -0.0272205 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0269085 |
| FBXO11 | F-box protein 11 | -0.0262905 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0261994 |
| DENND1A | DENN/MADD domain containing 1A | -0.0252913 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.025228 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0250459 |
| CAVIN1 | caveolae associated protein 1 | -0.0250039 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0246003 |
| RPL34 | ribosomal protein L34 | -0.0245992 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0238437 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0233688 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0233378 |
| DST | dystonin | -0.0231152 |
| RPL8 | ribosomal protein L8 | -0.0227849 |
| RPS25 | ribosomal protein S25 | -0.022751 |
| NHSL1 | NHS-like 1 | -0.0222484 |
| RAI1 | retinoic acid induced 1 | -0.0221057 |
| RPS16 | ribosomal protein S16 | -0.0219806 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0219515 |
| NEK10 | NIMA-related kinase 10 | -0.0219188 |
| TPM4 | tropomyosin 4 | -0.0218591 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0211065 |
| STK17A | serine/threonine kinase 17a | -0.0210093 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0208585 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0208013 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0206391 |
| RACK1 | receptor for activated C kinase 1 | -0.0200961 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0199046 |
| RPS19 | ribosomal protein S19 | -0.019679 |
| RPL7A | ribosomal protein L7a | -0.0196513 |
| RPL31 | ribosomal protein L31 | -0.019569 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0193387 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0191174 |
| S100A10 | S100 calcium binding protein A10 | -0.0189306 |
| TUBB6 | tubulin, beta 6 class V | -0.0188046 |
| INTS6 | integrator complex subunit 6 | -0.0185311 |
| PLIN2 | perilipin 2 | -0.0183441 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0182968 |
| S100A9 | S100 calcium binding protein A9 | -0.018222 |
| PKM | pyruvate kinase, muscle | -0.0182141 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0181688 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0180588 |
| EGR1 | early growth response 1 | -0.0177907 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.017778 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0177263 |
| PGM3 | phosphoglucomutase 3 | -0.0176583 |
| HM13 | histocompatibility (minor) 13 | -0.0174986 |
| WASF2 | WAS protein family, member 2 | -0.0173912 |
| KRT18 | keratin 18, type I | -0.0172769 |
| EGFR | epidermal growth factor receptor | -0.017205 |
