| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil (mesylate) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Belumosudil (mesylate)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0675233 |
| FAM20C | family with sequence similarity 20, member C | 0.0607665 |
| GLCCI1 | glucocorticoid induced 1 | 0.0536668 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.042988 |
| NTN4 | netrin 4 | 0.0305825 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0305502 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0297463 |
| SMAD3 | SMAD family member 3 | 0.0272619 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0258439 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0252628 |
| IFI44L | interferon-induced protein 44-like | 0.0250078 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0228275 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0226441 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0222171 |
| NRG1 | neuregulin 1 | 0.0216436 |
| KSR1 | kinase suppressor of ras 1 | 0.0209516 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0207699 |
| INTS6 | integrator complex subunit 6 | 0.0201631 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0201072 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0191071 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0185579 |
| RPL4 | ribosomal protein L4 | 0.0183206 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.017907 |
| AADAC | arylacetamide deacetylase | 0.0177784 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0174157 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0173263 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0168916 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0168522 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0161177 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0156265 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0154916 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0152317 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0151343 |
| IL1R1 | interleukin 1 receptor, type I | 0.0150273 |
| PLSCR1 | phospholipid scramblase 1 | 0.0148575 |
| TNNC1 | troponin C type 1 (slow) | 0.0148371 |
| VMP1 | vacuole membrane protein 1 | 0.014728 |
| VRK2 | vaccinia related kinase 2 | 0.0145255 |
| NLK | nemo-like kinase | 0.0144201 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0143643 |
| ANXA10 | annexin A10 | 0.0142442 |
| STK38L | serine/threonine kinase 38 like | 0.01417 |
| HDAC4 | histone deacetylase 4 | 0.0135873 |
| ETV6 | ets variant 6 | 0.0135601 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0134439 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0133212 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.013192 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0128898 |
| MEMO1 | mediator of cell motility 1 | 0.0124024 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0123102 |
| ANKRD36 | ankyrin repeat domain 36 | 0.012155 |
| PHF3 | PHD finger protein 3 | 0.0120416 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0120241 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0119819 |
| MEIS1 | Meis homeobox 1 | 0.0119371 |
| RAB27A | RAB27A, member RAS oncogene family | 0.0119258 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0118853 |
| RIGI | RNA sensor RIG-I | 0.0118607 |
| H1-0 | H1.0 linker histone | 0.0118606 |
| ZNF804A | zinc finger protein 804A | 0.0118483 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.011799 |
| RARB | retinoic acid receptor, beta | 0.0117778 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0116315 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0116073 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0115961 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.011582 |
| CTSC | cathepsin C | 0.0115611 |
| ETNK1 | ethanolamine kinase 1 | 0.0114369 |
| CDK14 | cyclin-dependent kinase 14 | 0.0112134 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0111539 |
| AVIL | advillin | 0.0111012 |
| KYNU | kynureninase | 0.011051 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0110427 |
| KIAA1328 | KIAA1328 | 0.0109631 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0108939 |
| FRMD4A | FERM domain containing 4A | 0.0107258 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0106952 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0106763 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0106519 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | 0.0106058 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0105959 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0104796 |
| NABP1 | nucleic acid binding protein 1 | 0.0104521 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0103179 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0101955 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.010185 |
| GLIS3 | GLIS family zinc finger 3 | 0.0101739 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0101181 |
| PRELID2 | PRELI domain containing 2 | 0.0100453 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0100452 |
| CPLANE1 | ciliogenesis and planar polarity effector complex subunit 1 | 0.00994037 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.00990195 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00989458 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.00985415 |
| RUNX2 | runt-related transcription factor 2 | 0.0098271 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.00970448 |
| IFI44 | interferon-induced protein 44 | 0.00965501 |
| TRIM22 | tripartite motif containing 22 | 0.00957831 |
| MX1 | MX dynamin-like GTPase 1 | 0.00957393 |
| ZNF644 | zinc finger protein 644 | 0.0094985 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.278318 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.216491 |
| TMSB10 | thymosin beta 10 | -0.17882 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.122891 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.11774 |
| FN1 | fibronectin 1 | -0.11529 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.105139 |
| STC1 | stanniocalcin 1 | -0.0983327 |
| FTL | ferritin, light polypeptide | -0.0961213 |
| NDRG1 | N-myc downstream regulated 1 | -0.0839079 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0739838 |
| PTMA | prothymosin, alpha | -0.0691594 |
| RPLP1 | ribosomal protein, large, P1 | -0.0683302 |
| CDH13 | cadherin 13 | -0.067701 |
| LOX | lysyl oxidase | -0.0668897 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0631997 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0626394 |
| MT2A | metallothionein 2A | -0.0605607 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0579355 |
| RPS19 | ribosomal protein S19 | -0.0571485 |
| S100A6 | S100 calcium binding protein A6 | -0.0567653 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0560432 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0550969 |
| HMGA1 | high mobility group AT-hook 1 | -0.0530154 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0523362 |
| RPL35A | ribosomal protein L35a | -0.0511955 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0497323 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0496251 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0495966 |
| TMSB4X | thymosin beta 4, X-linked | -0.0488073 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.04746 |
| PKM | pyruvate kinase, muscle | -0.0473338 |
| CDCP1 | CUB domain containing protein 1 | -0.0472477 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0471246 |
| USP34 | ubiquitin specific peptidase 34 | -0.0465069 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0446116 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0439879 |
| RPS6 | ribosomal protein S6 | -0.0438074 |
| CA12 | carbonic anhydrase XII | -0.0431295 |
| GOLGA4 | golgin A4 | -0.0429762 |
| RIOK3 | RIO kinase 3 | -0.0423651 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0419544 |
| PCBP2 | poly(rC) binding protein 2 | -0.0408669 |
| B2M | beta-2-microglobulin | -0.040742 |
| EGR1 | early growth response 1 | -0.0399641 |
| POTEF | POTE ankyrin domain family, member F | -0.0398882 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0396308 |
| IER3 | immediate early response 3 | -0.0390773 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0387937 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.038649 |
| RPS8 | ribosomal protein S8 | -0.0385905 |
| MAP1B | microtubule-associated protein 1B | -0.0382527 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0374778 |
| LDHA | lactate dehydrogenase A | -0.0374338 |
| FLNB | filamin B, beta | -0.0369361 |
| RPL31 | ribosomal protein L31 | -0.0362518 |
| S100A10 | S100 calcium binding protein A10 | -0.0353549 |
| FAM13A | family with sequence similarity 13, member A | -0.0350449 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0349246 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.034693 |
| RPLP2 | ribosomal protein, large, P2 | -0.0346356 |
| RPL37A | ribosomal protein L37a | -0.0341605 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0341392 |
| RPL34 | ribosomal protein L34 | -0.0340738 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0338442 |
| PGK1 | phosphoglycerate kinase 1 | -0.0327895 |
| CANX | calnexin | -0.0326013 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.032195 |
| RPS29 | ribosomal protein S29 | -0.0321659 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0320197 |
| RPLP0 | ribosomal protein, large, P0 | -0.0318473 |
| RPS21 | ribosomal protein S21 | -0.0317982 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0317212 |
| RPL23 | ribosomal protein L23 | -0.0309111 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.030444 |
| RPL36 | ribosomal protein L36 | -0.0297875 |
| ENO1 | enolase 1, (alpha) | -0.0297102 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0294799 |
| DST | dystonin | -0.0293505 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0292572 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0292001 |
| MEF2A | myocyte enhancer factor 2A | -0.0290865 |
| RPS12 | ribosomal protein S12 | -0.0290865 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.029042 |
| PYGL | phosphorylase, glycogen, liver | -0.0284317 |
| SYT1 | synaptotagmin I | -0.0282703 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0282022 |
| RPL37 | ribosomal protein L37 | -0.0280173 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0277175 |
| CALR | calreticulin | -0.0276141 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0275744 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.02734 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0269613 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0268774 |
| RPS13 | ribosomal protein S13 | -0.0265817 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0259581 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0258792 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0258211 |
| RAI1 | retinoic acid induced 1 | -0.0257249 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0253504 |
