| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil (mesylate) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Belumosudil (mesylate)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TSC22D2 | TSC22 domain family, member 2 | 0.0708639 |
| ZNF292 | zinc finger protein 292 | 0.0593648 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0578601 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0516177 |
| PEG10 | paternally expressed 10 | 0.047165 |
| HDAC9 | histone deacetylase 9 | 0.0440874 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0427657 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0408832 |
| FOXP2 | forkhead box P2 | 0.0402205 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0394853 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.035758 |
| SYT1 | synaptotagmin I | 0.0348296 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0315976 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0305639 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0305574 |
| ENAH | enabled homolog (Drosophila) | 0.0304751 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0294257 |
| RIGI | RNA sensor RIG-I | 0.0293997 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0293119 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0289489 |
| MEF2C | myocyte enhancer factor 2C | 0.0277574 |
| TMEM64 | transmembrane protein 64 | 0.0276386 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0271711 |
| CDK6 | cyclin-dependent kinase 6 | 0.0271334 |
| NTM | neurotrimin | 0.0264675 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0262829 |
| ANXA1 | annexin A1 | 0.0260227 |
| RPL4 | ribosomal protein L4 | 0.0260084 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0259609 |
| RBM20 | RNA binding motif protein 20 | 0.0258837 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0257235 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0238103 |
| XPO1 | exportin 1 | 0.0235986 |
| BRD2 | bromodomain containing 2 | 0.0233967 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.023183 |
| OLA1 | Obg-like ATPase 1 | 0.0230366 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0227502 |
| MTF2 | metal response element binding transcription factor 2 | 0.0227039 |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.0221966 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0219146 |
| MDN1 | MDN1, midasin homolog (yeast) | 0.0215952 |
| NELL2 | NEL-like 2 (chicken) | 0.0212793 |
| CCN2 | cellular communication network factor 2 | 0.021274 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0210317 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0208647 |
| ZFR | zinc finger RNA binding protein | 0.0205814 |
| CLASP1 | cytoplasmic linker associated protein 1 | 0.0205024 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0201666 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0201512 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0199686 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0198149 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0197974 |
| DIDO1 | death inducer-obliterator 1 | 0.0197932 |
| FOXG1 | forkhead box G1 | 0.0197003 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.019561 |
| NUP153 | nucleoporin 153kDa | 0.0194518 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0192842 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0188286 |
| FGFR1OP2 | FGFR1 oncogene partner 2 | 0.0188005 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0187149 |
| WDR43 | WD repeat domain 43 | 0.0186063 |
| RLF | rearranged L-myc fusion | 0.0184672 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0183801 |
| ATF6 | activating transcription factor 6 | 0.0182623 |
| PRTG | protogenin | 0.0182208 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0179656 |
| ECT2 | epithelial cell transforming 2 | 0.0179636 |
| CTPS1 | CTP synthase 1 | 0.0179205 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0179055 |
| H1-4 | H1.4 linker histone, cluster member | 0.0178658 |
| POGZ | pogo transposable element with ZNF domain | 0.017812 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0176977 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0174838 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0174072 |
| RPL21 | ribosomal protein L21 | 0.0171356 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0170958 |
| USP53 | ubiquitin specific peptidase 53 | 0.0170708 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.016866 |
| RHEB | Ras homolog enriched in brain | 0.0168405 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 0.0167558 |
| RFX7 | regulatory factor X, 7 | 0.0167342 |
| DGKH | diacylglycerol kinase, eta | 0.0167246 |
| KIF1B | kinesin family member 1B | 0.0166991 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0166558 |
| PHF21A | PHD finger protein 21A | 0.0166296 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0166191 |
| AFG3L2 | AFG3-like AAA ATPase 2 | 0.016504 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0164776 |
| ZNF516 | zinc finger protein 516 | 0.0164631 |
| TPM3 | tropomyosin 3 | 0.0164443 |
| RPL3 | ribosomal protein L3 | 0.0164014 |
| ADCY9 | adenylate cyclase 9 | 0.0163554 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0163052 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0162527 |
| MEMO1 | mediator of cell motility 1 | 0.0161468 |
| PCDH18 | protocadherin 18 | 0.0160687 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0160573 |
| GPC4 | glypican 4 | 0.0160094 |
| NCKAP1 | NCK-associated protein 1 | 0.0159061 |
| PAPOLA | poly(A) polymerase alpha | 0.0158866 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.196823 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.153091 |
| PTMA | prothymosin, alpha | -0.143346 |
| TMSB10 | thymosin beta 10 | -0.130053 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.117702 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0958946 |
| PCDH9 | protocadherin 9 | -0.092887 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0679685 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0671031 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0649841 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0648665 |
| RPL35A | ribosomal protein L35a | -0.0623825 |
| COL3A1 | collagen, type III, alpha 1 | -0.0622593 |
| ACTG1 | actin gamma 1 | -0.0615202 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0563708 |
| RPL31 | ribosomal protein L31 | -0.055091 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0515289 |
| CADM2 | cell adhesion molecule 2 | -0.0507498 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0507364 |
| RAD51B | RAD51 paralog B | -0.0493776 |
| FTL | ferritin, light polypeptide | -0.0478264 |
| EMP1 | epithelial membrane protein 1 | -0.0466276 |
| GNAS | GNAS complex locus | -0.046269 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0444925 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0443064 |
| LDHA | lactate dehydrogenase A | -0.0440242 |
| RPS6 | ribosomal protein S6 | -0.0436227 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0431241 |
| S100A10 | S100 calcium binding protein A10 | -0.0430275 |
| FN1 | fibronectin 1 | -0.0430204 |
| B2M | beta-2-microglobulin | -0.042998 |
| AHNAK | AHNAK nucleoprotein | -0.0423872 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0409547 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0408376 |
| RPL34 | ribosomal protein L34 | -0.0407228 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0396512 |
| RPL19 | ribosomal protein L19 | -0.0395303 |
| RPLP0 | ribosomal protein, large, P0 | -0.0394316 |
| RPS21 | ribosomal protein S21 | -0.0376086 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0374646 |
| RPL23 | ribosomal protein L23 | -0.0372047 |
| HMGB1 | high mobility group box 1 | -0.0368123 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0363395 |
| CBX3 | chromobox homolog 3 | -0.0360622 |
| RPS8 | ribosomal protein S8 | -0.0359744 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0356977 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0353036 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0348658 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.034423 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0338023 |
| TENM3 | teneurin transmembrane protein 3 | -0.0335622 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0333017 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0332864 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0332779 |
| LRRC4C | leucine rich repeat containing 4C | -0.0329836 |
| RPL37A | ribosomal protein L37a | -0.0329393 |
| SPAG9 | sperm associated antigen 9 | -0.0326815 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0326023 |
| HMGA1 | high mobility group AT-hook 1 | -0.0323444 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0315195 |
| NDRG1 | N-myc downstream regulated 1 | -0.0314499 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0311262 |
| PGK1 | phosphoglycerate kinase 1 | -0.0305261 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0304996 |
| RSF1 | remodeling and spacing factor 1 | -0.0304613 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0302524 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.030039 |
| RPS19 | ribosomal protein S19 | -0.029864 |
| RPS25 | ribosomal protein S25 | -0.0296817 |
| FBXO11 | F-box protein 11 | -0.0295624 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0293389 |
| TRIM2 | tripartite motif containing 2 | -0.0291291 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0290396 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0289938 |
| RTN4 | reticulon 4 | -0.0289236 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0287307 |
| RPL28 | ribosomal protein L28 | -0.0286744 |
| PKM | pyruvate kinase, muscle | -0.028603 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.028498 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0284159 |
| RPL11 | ribosomal protein L11 | -0.028296 |
| CANX | calnexin | -0.0282553 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0277932 |
| SGO2 | shugoshin 2 | -0.0275948 |
| TPM4 | tropomyosin 4 | -0.0273534 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0273377 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0273042 |
| FRY | furry homolog (Drosophila) | -0.0271457 |
| MT2A | metallothionein 2A | -0.0270571 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0269559 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0267773 |
| HMGA2 | high mobility group AT-hook 2 | -0.0265201 |
| FMNL2 | formin-like 2 | -0.0263365 |
| RPS24 | ribosomal protein S24 | -0.0261573 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0258611 |
| RPL27A | ribosomal protein L27a | -0.0258519 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0256433 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | -0.0255294 |
| RPS16 | ribosomal protein S16 | -0.0253474 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0253454 |
