| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil (mesylate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Belumosudil (mesylate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.382403 |
| VIM | vimentin | 0.18536 |
| FBL | fibrillarin | 0.119228 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.114889 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0872205 |
| PTMA | prothymosin, alpha | 0.0678472 |
| RPS16 | ribosomal protein S16 | 0.0604543 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0556007 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0498429 |
| ZFP36 | ZFP36 ring finger protein | 0.0492432 |
| H1-0 | H1.0 linker histone | 0.0486545 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0462548 |
| JMJD1C | jumonji domain containing 1C | 0.0444244 |
| S100A6 | S100 calcium binding protein A6 | 0.0442518 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0419221 |
| TXNRD1 | thioredoxin reductase 1 | 0.0411877 |
| RPL4 | ribosomal protein L4 | 0.0399162 |
| ANXA2 | annexin A2 | 0.0382572 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0371353 |
| MKI67 | marker of proliferation Ki-67 | 0.0368734 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0350072 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0346452 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0324716 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0315055 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0314694 |
| UBC | ubiquitin C | 0.0310146 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0306472 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0295178 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0284756 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.028122 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0280082 |
| MAP1B | microtubule-associated protein 1B | 0.0276456 |
| ANGPTL4 | angiopoietin-like 4 | 0.0268435 |
| ARRDC3 | arrestin domain containing 3 | 0.0267823 |
| SNX9 | sorting nexin 9 | 0.0264745 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0262998 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0257082 |
| CD44 | CD44 molecule (Indian blood group) | 0.0243406 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0234872 |
| CDK19 | cyclin-dependent kinase 19 | 0.0231765 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0231504 |
| PDGFB | platelet-derived growth factor beta polypeptide | 0.0221395 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0218917 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0218405 |
| ANLN | anillin, actin binding protein | 0.0215349 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0215076 |
| KLF6 | Kruppel-like factor 6 | 0.0204601 |
| TPD52 | tumor protein D52 | 0.019902 |
| TPX2 | TPX2, microtubule-associated | 0.019561 |
| FBXO17 | F-box protein 17 | 0.0194937 |
| SBF2 | SET binding factor 2 | 0.0193141 |
| CDCP1 | CUB domain containing protein 1 | 0.0190946 |
| MLF1 | myeloid leukemia factor 1 | 0.0189527 |
| LRP11 | low density lipoprotein receptor-related protein 11 | 0.0182283 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0181568 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0177862 |
| TMEM123 | transmembrane protein 123 | 0.0176609 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0175755 |
| VMP1 | vacuole membrane protein 1 | 0.0174032 |
| AFAP1 | actin filament associated protein 1 | 0.0172935 |
| ZNF292 | zinc finger protein 292 | 0.0171923 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.016587 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0165126 |
| TMEM41B | transmembrane protein 41B | 0.0162708 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0162175 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0162013 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0161205 |
| SQSTM1 | sequestosome 1 | 0.0158365 |
| SESN2 | sestrin 2 | 0.0157843 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0153513 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0152439 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 0.0152243 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0151299 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0150784 |
| MATR3 | matrin 3 | 0.0150361 |
| ENO1 | enolase 1, (alpha) | 0.0148651 |
| IPO7 | importin 7 | 0.0147452 |
| AXL | AXL receptor tyrosine kinase | 0.0147145 |
| ATF6 | activating transcription factor 6 | 0.0144794 |
| YBX3 | Y box binding protein 3 | 0.0142601 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0141926 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0141396 |
| ATF3 | activating transcription factor 3 | 0.0139112 |
| ADM | adrenomedullin | 0.0137508 |
| GOLT1A | golgi transport 1A | 0.013727 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0136673 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0136241 |
| YEATS2 | YEATS domain containing 2 | 0.0136136 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0136058 |
| FHL2 | four and a half LIM domains 2 | 0.0134248 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0131917 |
| SFTPA2 | surfactant protein A2 | 0.0131734 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0131024 |
| CEP170 | centrosomal protein 170kDa | 0.01295 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0129419 |
| RPL3 | ribosomal protein L3 | 0.0127082 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0126574 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0125635 |
| VGLL4 | vestigial-like family member 4 | 0.0124623 |
| WASF2 | WAS protein family, member 2 | 0.0123733 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.195875 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.169147 |
| VCL | vinculin | -0.153098 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.101133 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0934581 |
| TMSB10 | thymosin beta 10 | -0.0887529 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0808111 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0750752 |
| RPLP2 | ribosomal protein, large, P2 | -0.0750654 |
| MT2A | metallothionein 2A | -0.0742496 |
| RPL37A | ribosomal protein L37a | -0.0665773 |
| ACTN4 | actinin, alpha 4 | -0.062668 |
| INTS6 | integrator complex subunit 6 | -0.0621333 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0607845 |
| RPS3 | ribosomal protein S3 | -0.0602216 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0574692 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.056879 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0562667 |
| RPS12 | ribosomal protein S12 | -0.0559874 |
| DST | dystonin | -0.0522782 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0511644 |
| RPL11 | ribosomal protein L11 | -0.0494261 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | -0.045602 |
| HMGA2 | high mobility group AT-hook 2 | -0.0443202 |
| TNS3 | tensin 3 | -0.0435006 |
| CALR | calreticulin | -0.0432423 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0408413 |
| NAV2 | neuron navigator 2 | -0.0406286 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0403088 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.039622 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0391446 |
| ASPH | aspartate beta-hydroxylase | -0.0385753 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0381262 |
| ATM | ATM serine/threonine kinase | -0.0380824 |
| RPL38 | ribosomal protein L38 | -0.0374408 |
| RAD51B | RAD51 paralog B | -0.0372866 |
| SEPTIN9 | septin 9 | -0.036577 |
| RPS27A | ribosomal protein S27a | -0.03654 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0361121 |
| ATG7 | autophagy related 7 | -0.0355327 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0353021 |
| TPM1 | tropomyosin 1 (alpha) | -0.0351348 |
| CTBP2 | C-terminal binding protein 2 | -0.0347785 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0344176 |
| RPS8 | ribosomal protein S8 | -0.0338225 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0337781 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.0336685 |
| PTK2 | protein tyrosine kinase 2 | -0.0320002 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0313903 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0312432 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0311115 |
| FLNA | filamin A, alpha | -0.0306131 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0302383 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0301204 |
| SETX | senataxin | -0.0300605 |
| RPS29 | ribosomal protein S29 | -0.029201 |
| EXOC4 | exocyst complex component 4 | -0.0291786 |
| RPL9 | ribosomal protein L9 | -0.0289582 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0286925 |
| NOP56 | NOP56 ribonucleoprotein | -0.0285731 |
| RPLP1 | ribosomal protein, large, P1 | -0.0285471 |
| NEK10 | NIMA-related kinase 10 | -0.0285092 |
| RPL28 | ribosomal protein L28 | -0.0284913 |
| NUP98 | nucleoporin 98kDa | -0.0284116 |
| FMNL2 | formin-like 2 | -0.028127 |
| CMIP | c-Maf inducing protein | -0.0279694 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0277972 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0276926 |
| AHNAK | AHNAK nucleoprotein | -0.0275714 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0275254 |
| RPS23 | ribosomal protein S23 | -0.0275028 |
| HM13 | histocompatibility (minor) 13 | -0.0272076 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0270503 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0268475 |
| EFNA5 | ephrin-A5 | -0.0264337 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0264184 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0263341 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0262954 |
| DIAPH2 | diaphanous-related formin 2 | -0.0261674 |
| CANX | calnexin | -0.0259777 |
| RSU1 | Ras suppressor protein 1 | -0.0259163 |
| ZNF780B | zinc finger protein 780B | -0.0258628 |
| RPS24 | ribosomal protein S24 | -0.0258283 |
| ACTG1 | actin gamma 1 | -0.0256668 |
| RPS19 | ribosomal protein S19 | -0.0255335 |
| MORF4L2 | mortality factor 4 like 2 | -0.0251 |
| B2M | beta-2-microglobulin | -0.0249318 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0248649 |
| SMYD3 | SET and MYND domain containing 3 | -0.0247557 |
| RPL36 | ribosomal protein L36 | -0.0247265 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0245749 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0244545 |
| MCL1 | myeloid cell leukemia 1 | -0.0243625 |
| GOLGB1 | golgin B1 | -0.0243346 |
| EGR1 | early growth response 1 | -0.0241878 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0240529 |
| RPL31 | ribosomal protein L31 | -0.0239016 |
| SPAG9 | sperm associated antigen 9 | -0.0237747 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0236186 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.0235186 |
