| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil (mesylate) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Belumosudil (mesylate)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.133907 |
| NRXN3 | neurexin 3 | 0.0915404 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.084092 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0618679 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0597423 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0505831 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0483103 |
| FNIP1 | folliculin interacting protein 1 | 0.046655 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.046544 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0443332 |
| NAV1 | neuron navigator 1 | 0.0427 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0378012 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0371361 |
| FAM13A | family with sequence similarity 13, member A | 0.0370114 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0368708 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0366918 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0353831 |
| STC1 | stanniocalcin 1 | 0.0349191 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0333482 |
| SEC24A | SEC24 family member A | 0.0324122 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0312332 |
| RAI14 | retinoic acid induced 14 | 0.0307303 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.029783 |
| SBF2 | SET binding factor 2 | 0.029236 |
| MORF4L2 | mortality factor 4 like 2 | 0.0289157 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0286742 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.027826 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0277389 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0276643 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.027557 |
| LOXL2 | lysyl oxidase-like 2 | 0.0272747 |
| CDH13 | cadherin 13 | 0.026665 |
| LAMB1 | laminin, beta 1 | 0.0265663 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0263292 |
| NBEAL1 | neurobeachin-like 1 | 0.0255637 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0253095 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.024862 |
| RNF145 | ring finger protein 145 | 0.0246472 |
| GOLGB1 | golgin B1 | 0.0239968 |
| EFNA5 | ephrin-A5 | 0.0239911 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0238511 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0234286 |
| TMF1 | TATA element modulatory factor 1 | 0.0232807 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0231992 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0231737 |
| GLIS3 | GLIS family zinc finger 3 | 0.0230826 |
| MKI67 | marker of proliferation Ki-67 | 0.0230277 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0229603 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0228137 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0227517 |
| FMNL2 | formin-like 2 | 0.0224148 |
| SFXN1 | sideroflexin 1 | 0.0220772 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0220644 |
| PRELID2 | PRELI domain containing 2 | 0.0216766 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0216057 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0215483 |
| HMGA2 | high mobility group AT-hook 2 | 0.0213895 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.021364 |
| RIN2 | Ras and Rab interactor 2 | 0.0211137 |
| OXR1 | oxidation resistance 1 | 0.0210777 |
| COG5 | component of oligomeric golgi complex 5 | 0.0210043 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0209074 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0209029 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0207545 |
| JPH2 | junctophilin 2 | 0.0207108 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | 0.0205774 |
| HIP1 | huntingtin interacting protein 1 | 0.0205544 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.0204856 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0204322 |
| NBAS | neuroblastoma amplified sequence | 0.0202701 |
| OXSR1 | oxidative stress responsive 1 | 0.0201667 |
| PDGFC | platelet derived growth factor C | 0.0200784 |
| TANK | TRAF family member-associated NFKB activator | 0.0200498 |
| NKTR | natural killer cell triggering receptor | 0.0199828 |
| ZNF133 | zinc finger protein 133 | 0.0196364 |
| MYOF | myoferlin | 0.0195525 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0195517 |
| NFX1 | nuclear transcription factor, X-box binding 1 | 0.019473 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0194239 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0194188 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0193901 |
| KYNU | kynureninase | 0.0193547 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0193209 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0192707 |
| CA12 | carbonic anhydrase XII | 0.0192434 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0191103 |
| ZNF638 | zinc finger protein 638 | 0.0189788 |
| GOLGA4 | golgin A4 | 0.0189034 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0188008 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0187682 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0185543 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0184461 |
| FCHO2 | FCH domain only 2 | 0.0183183 |
| SUCO | SUN domain containing ossification factor | 0.0183131 |
| PRSS23 | protease, serine, 23 | 0.0182814 |
| VEGFC | vascular endothelial growth factor C | 0.0182351 |
| FSCN1 | fascin actin-bundling protein 1 | 0.0182057 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0181997 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 0.0181522 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0181132 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.196431 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.135077 |
| MT2A | metallothionein 2A | -0.0921065 |
| VIM | vimentin | -0.0895301 |
| FN1 | fibronectin 1 | -0.0852893 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0829906 |
| ENO1 | enolase 1, (alpha) | -0.0763128 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0669211 |
| ANXA5 | annexin A5 | -0.062439 |
| RPL37A | ribosomal protein L37a | -0.0599438 |
| PTMA | prothymosin, alpha | -0.0590001 |
| SPAG9 | sperm associated antigen 9 | -0.0587457 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0551552 |
| UBC | ubiquitin C | -0.054946 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0538818 |
| COL1A2 | collagen, type I, alpha 2 | -0.0520487 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0516209 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0507802 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0493393 |
| TXNIP | thioredoxin interacting protein | -0.0487836 |
| LDHA | lactate dehydrogenase A | -0.0477615 |
| POTEF | POTE ankyrin domain family, member F | -0.0476985 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.044562 |
| CCNI | cyclin I | -0.0425873 |
| COL1A1 | collagen, type I, alpha 1 | -0.0420679 |
| RTN4 | reticulon 4 | -0.0414675 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0410051 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0397232 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.038748 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0385334 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0377442 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0361417 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0359738 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0359214 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0357333 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0353297 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.035192 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0350677 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.0346366 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0345482 |
| IL6 | interleukin 6 | -0.0344029 |
| FLNA | filamin A, alpha | -0.0341663 |
| WTAP | Wilms tumor 1 associated protein | -0.0335893 |
| ACTG1 | actin gamma 1 | -0.0335065 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0334406 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0334192 |
| TPM4 | tropomyosin 4 | -0.0332801 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.033154 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0330792 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0326871 |
| SRPK2 | SRSF protein kinase 2 | -0.0326806 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0325887 |
| RPLP1 | ribosomal protein, large, P1 | -0.0325314 |
| FLNB | filamin B, beta | -0.0324045 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0320474 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0310218 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0308939 |
| JUN | jun proto-oncogene | -0.0306569 |
| LONP2 | lon peptidase 2, peroxisomal | -0.0298175 |
| TOP1 | topoisomerase (DNA) I | -0.0297999 |
| RIGI | RNA sensor RIG-I | -0.0297535 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0296661 |
| FAM3C | family with sequence similarity 3, member C | -0.0295333 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0289006 |
| S100A9 | S100 calcium binding protein A9 | -0.0284556 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0283545 |
| RPS27A | ribosomal protein S27a | -0.0280314 |
| ZNF207 | zinc finger protein 207 | -0.0279953 |
| GANAB | glucosidase, alpha; neutral AB | -0.0277578 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0273383 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0268778 |
| PCBP2 | poly(rC) binding protein 2 | -0.0267804 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0266879 |
| RPS13 | ribosomal protein S13 | -0.0263099 |
| COL5A2 | collagen, type V, alpha 2 | -0.026151 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0258784 |
| RPS11 | ribosomal protein S11 | -0.0258745 |
| PKM | pyruvate kinase, muscle | -0.0257405 |
| RPL23 | ribosomal protein L23 | -0.0256188 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0256001 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0254788 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0252122 |
| SCARB2 | scavenger receptor class B, member 2 | -0.0248154 |
| SEC61G | Sec61 gamma subunit | -0.0247618 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0245812 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | -0.0243185 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0242237 |
| OAZ1 | ornithine decarboxylase antizyme 1 | -0.0242073 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0241739 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0241706 |
| SEPTIN7 | septin 7 | -0.0241685 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0238808 |
| CENPF | centromere protein F, 350/400kDa | -0.0237706 |
| MCL1 | myeloid cell leukemia 1 | -0.0237693 |
| AFDN | afadin, adherens junction formation factor | -0.023699 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0236041 |
| PDE8A | phosphodiesterase 8A | -0.0235793 |
| DEK | DEK proto-oncogene | -0.0234871 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0232598 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0231913 |
