| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil (mesylate) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Belumosudil (mesylate)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.10399 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0721442 |
| INTS6 | integrator complex subunit 6 | 0.0650984 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0637699 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.060318 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0572296 |
| GOLGB1 | golgin B1 | 0.0550768 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0548253 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0516637 |
| ANXA1 | annexin A1 | 0.0500564 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0489118 |
| RPL4 | ribosomal protein L4 | 0.0487946 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0479631 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0465509 |
| SQSTM1 | sequestosome 1 | 0.0405938 |
| GOLGA4 | golgin A4 | 0.038875 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.038604 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0382358 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0372762 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0364695 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.036448 |
| SMAD3 | SMAD family member 3 | 0.0354634 |
| PCBP2 | poly(rC) binding protein 2 | 0.0350225 |
| ZNF292 | zinc finger protein 292 | 0.0326904 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0321102 |
| OXSR1 | oxidative stress responsive 1 | 0.0320931 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0310778 |
| UBC | ubiquitin C | 0.0308479 |
| NABP1 | nucleic acid binding protein 1 | 0.0306594 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0296126 |
| SET | SET nuclear proto-oncogene | 0.029105 |
| JMJD1C | jumonji domain containing 1C | 0.0290146 |
| TPX2 | TPX2, microtubule-associated | 0.0283935 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0278422 |
| HELZ | helicase with zinc finger | 0.0278 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0272233 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0263509 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.026264 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0254608 |
| BRD2 | bromodomain containing 2 | 0.0252927 |
| CENPE | centromere protein E, 312kDa | 0.0248491 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0244563 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0244249 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0242636 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0234742 |
| NGLY1 | N-glycanase 1 | 0.023462 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0233827 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0233374 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0232975 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0230571 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.022643 |
| TOP1 | topoisomerase (DNA) I | 0.0226205 |
| RAB1A | RAB1A, member RAS oncogene family | 0.022459 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0222826 |
| AHI1 | Abelson helper integration site 1 | 0.022175 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0221121 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0219555 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0218297 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0217583 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0216673 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0216182 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0215019 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0212603 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0212237 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0206746 |
| YBX3 | Y box binding protein 3 | 0.0205473 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0205433 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0204846 |
| NUP58 | nucleoporin 58 | 0.0201791 |
| MORF4L2 | mortality factor 4 like 2 | 0.0200632 |
| YBX1 | Y box binding protein 1 | 0.020051 |
| TXNRD1 | thioredoxin reductase 1 | 0.0199335 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.0198152 |
| FNIP1 | folliculin interacting protein 1 | 0.0197374 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0195025 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0194977 |
| ANO10 | anoctamin 10 | 0.0191556 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0190593 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.0190254 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0189363 |
| SMAD2 | SMAD family member 2 | 0.0188942 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0187492 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0185632 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.018559 |
| SIK2 | salt-inducible kinase 2 | 0.0184355 |
| GPHN | gephyrin | 0.018322 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0183215 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0182967 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0182933 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0182866 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.018181 |
| RDX | radixin | 0.0181452 |
| PNN | pinin, desmosome associated protein | 0.0179548 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0179472 |
| COG6 | component of oligomeric golgi complex 6 | 0.0177824 |
| CERT1 | ceramide transporter 1 | 0.0177368 |
| TLE4 | transducin-like enhancer of split 4 | 0.0177192 |
| ADIPOR2 | adiponectin receptor 2 | 0.0177188 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0176928 |
| RPS2 | ribosomal protein S2 | 0.0176214 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.183966 |
| TMSB10 | thymosin beta 10 | -0.155714 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0976089 |
| IGF2 | insulin-like growth factor 2 | -0.0813687 |
| PRSS23 | protease, serine, 23 | -0.0740472 |
| PTMA | prothymosin, alpha | -0.0721237 |
| LDHA | lactate dehydrogenase A | -0.066552 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0650055 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0621852 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0611196 |
| CD44 | CD44 molecule (Indian blood group) | -0.0599696 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0593008 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0591364 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0579098 |
| HMGA2 | high mobility group AT-hook 2 | -0.0578074 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0566125 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0563334 |
| FLNB | filamin B, beta | -0.0556743 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0547757 |
| ATM | ATM serine/threonine kinase | -0.054542 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0537407 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.050815 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0496655 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0490187 |
| PRR16 | proline rich 16 | -0.0483279 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0478466 |
| DNER | delta/notch-like EGF repeat containing | -0.0464526 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0462348 |
| ANGPTL4 | angiopoietin-like 4 | -0.0444214 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0442105 |
| POTEF | POTE ankyrin domain family, member F | -0.0435193 |
| VCL | vinculin | -0.0426933 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0425062 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0424627 |
| RPL35A | ribosomal protein L35a | -0.0422584 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.042008 |
| PODXL | podocalyxin-like | -0.0415701 |
| PGK1 | phosphoglycerate kinase 1 | -0.0402544 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0402518 |
| NALCN | sodium leak channel, non selective | -0.0393469 |
| CCDC91 | coiled-coil domain containing 91 | -0.0389852 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0382677 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0353767 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0345637 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0337582 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0331868 |
| PYGL | phosphorylase, glycogen, liver | -0.0317677 |
| ACTG1 | actin gamma 1 | -0.0317291 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0316813 |
| ANXA2 | annexin A2 | -0.0314102 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0306995 |
| GPC6 | glypican 6 | -0.0305092 |
| PTK2 | protein tyrosine kinase 2 | -0.0300911 |
| MCL1 | myeloid cell leukemia 1 | -0.0297392 |
| MT2A | metallothionein 2A | -0.0295484 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0294274 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0293249 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0292768 |
| SMYD3 | SET and MYND domain containing 3 | -0.0291646 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0290903 |
| OSMR | oncostatin M receptor | -0.0290164 |
| RAI14 | retinoic acid induced 14 | -0.0288085 |
| RAD51B | RAD51 paralog B | -0.0287192 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0286243 |
| B2M | beta-2-microglobulin | -0.0285168 |
| TPM4 | tropomyosin 4 | -0.0280835 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0280494 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0277677 |
| ATXN1 | ataxin 1 | -0.0275947 |
| NDRG1 | N-myc downstream regulated 1 | -0.0275242 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0275146 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0274464 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0271855 |
| LAMB1 | laminin, beta 1 | -0.0271391 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0268198 |
| NF1 | neurofibromin 1 | -0.0267384 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0262865 |
| AFDN | afadin, adherens junction formation factor | -0.0260728 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0258875 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0258401 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0258043 |
| EFNA5 | ephrin-A5 | -0.0256568 |
| VMP1 | vacuole membrane protein 1 | -0.025102 |
| CD59 | CD59 molecule, complement regulatory protein | -0.025064 |
| GNAS | GNAS complex locus | -0.0249289 |
| HLA-B | major histocompatibility complex, class I, B | -0.0247185 |
| COL5A1 | collagen, type V, alpha 1 | -0.0246585 |
| THBS1 | thrombospondin 1 | -0.0244233 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0241537 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0240755 |
| DENND5B | DENN/MADD domain containing 5B | -0.0240619 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0238945 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0237306 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0236265 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0232845 |
| MATR3 | matrin 3 | -0.0230516 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0227054 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0226762 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0225175 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0223522 |
