| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil (mesylate) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Belumosudil (mesylate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.168167 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.163982 |
| FTL | ferritin, light polypeptide | 0.151024 |
| PTMA | prothymosin, alpha | 0.10899 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0965561 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0843693 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0729973 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0619261 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0567471 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0525245 |
| UBC | ubiquitin C | 0.0525196 |
| WWC1 | WW and C2 domain containing 1 | 0.0514927 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0485441 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0476897 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0471676 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0428369 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0426855 |
| MYO1E | myosin IE | 0.0426095 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0426077 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0416606 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0411291 |
| PCBP2 | poly(rC) binding protein 2 | 0.0411234 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0391478 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.0390712 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0382353 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0379285 |
| PKM | pyruvate kinase, muscle | 0.037567 |
| SPAG9 | sperm associated antigen 9 | 0.0348871 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0343872 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0338368 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0328949 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0328525 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0324466 |
| SETD5 | SET domain containing 5 | 0.0321934 |
| GOLGA4 | golgin A4 | 0.0316586 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0314362 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.030957 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0302607 |
| MED13 | mediator complex subunit 13 | 0.030124 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0297923 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0293867 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0288247 |
| INTS6 | integrator complex subunit 6 | 0.0288043 |
| RCOR1 | REST corepressor 1 | 0.028052 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0279791 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0279158 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0278562 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0276249 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0273731 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0272791 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | 0.0270733 |
| GNAS | GNAS complex locus | 0.0267109 |
| OXR1 | oxidation resistance 1 | 0.0266984 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0264577 |
| CDK13 | cyclin-dependent kinase 13 | 0.0263008 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0261982 |
| RBM25 | RNA binding motif protein 25 | 0.026005 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0259616 |
| BRD2 | bromodomain containing 2 | 0.0254841 |
| LIMA1 | LIM domain and actin binding 1 | 0.0252951 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0249451 |
| SET | SET nuclear proto-oncogene | 0.0246359 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0244347 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.024256 |
| LMNA | lamin A/C | 0.0241955 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0239806 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | 0.023819 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0237409 |
| SMAD3 | SMAD family member 3 | 0.0237048 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0230005 |
| COBL | cordon-bleu WH2 repeat protein | 0.0228106 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0227546 |
| UBAP2 | ubiquitin associated protein 2 | 0.0226756 |
| SON | SON DNA binding protein | 0.0223698 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0222929 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0220897 |
| SMAD2 | SMAD family member 2 | 0.0217215 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0216735 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0216389 |
| OXSR1 | oxidative stress responsive 1 | 0.021527 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0215262 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0213757 |
| POTEF | POTE ankyrin domain family, member F | 0.0212003 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.020962 |
| YY1 | YY1 transcription factor | 0.0208277 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0206499 |
| MSI2 | musashi RNA-binding protein 2 | 0.0205053 |
| PNN | pinin, desmosome associated protein | 0.0204903 |
| CBX3 | chromobox homolog 3 | 0.0204773 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0203767 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0203458 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.020249 |
| RND3 | Rho family GTPase 3 | 0.0201759 |
| CST3 | cystatin C | 0.0200118 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0198574 |
| GPHN | gephyrin | 0.0198542 |
| MCU | mitochondrial calcium uniporter | 0.0196623 |
| GSTP1 | glutathione S-transferase pi 1 | 0.0195316 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0192453 |
| TPM3 | tropomyosin 3 | 0.0191533 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0978195 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.081909 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0574889 |
| TMSB10 | thymosin beta 10 | -0.056056 |
| KRT8 | keratin 8, type II | -0.0559978 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0544688 |
| RPS12 | ribosomal protein S12 | -0.052399 |
| RPL37A | ribosomal protein L37a | -0.0520854 |
| ACTN4 | actinin, alpha 4 | -0.0518198 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0477934 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0460169 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0438422 |
| CCND1 | cyclin D1 | -0.0421477 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0380689 |
| PRELID2 | PRELI domain containing 2 | -0.0376342 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0367772 |
| RPS21 | ribosomal protein S21 | -0.034975 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0341115 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0340426 |
| BCL2L1 | BCL2-like 1 | -0.0340115 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0337999 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0333373 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0332547 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0330207 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0318725 |
| IER3 | immediate early response 3 | -0.0316068 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0315318 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0313832 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0309329 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0309072 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.029791 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0296125 |
| TXNRD1 | thioredoxin reductase 1 | -0.0294707 |
| PLEC | plectin | -0.0294673 |
| RPS29 | ribosomal protein S29 | -0.0293721 |
| CANX | calnexin | -0.0290665 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0285367 |
| OGA | O-GlcNAcase | -0.0283207 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0281201 |
| RPLP2 | ribosomal protein, large, P2 | -0.0269948 |
| AHNAK | AHNAK nucleoprotein | -0.0268677 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0264215 |
| MAP4 | microtubule-associated protein 4 | -0.0261831 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0255226 |
| RPL26 | ribosomal protein L26 | -0.0253372 |
| IPO7 | importin 7 | -0.0252743 |
| DST | dystonin | -0.0248833 |
| FAT1 | FAT atypical cadherin 1 | -0.0246468 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0244414 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0233956 |
| ITGB4 | integrin, beta 4 | -0.0233767 |
| EZR | ezrin | -0.0230826 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0227708 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0223338 |
| ADAR | adenosine deaminase, RNA-specific | -0.0218341 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0217863 |
| AFDN | afadin, adherens junction formation factor | -0.0217579 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | -0.0215288 |
| VMP1 | vacuole membrane protein 1 | -0.0215033 |
| RPL23 | ribosomal protein L23 | -0.0214168 |
| CALU | calumenin | -0.0213691 |
| RPS27A | ribosomal protein S27a | -0.0211645 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0211406 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0209512 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0207545 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0205809 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0205369 |
| PLSCR1 | phospholipid scramblase 1 | -0.0205237 |
| ZNF217 | zinc finger protein 217 | -0.0203672 |
| RPS13 | ribosomal protein S13 | -0.0203603 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0201799 |
| RPL30 | ribosomal protein L30 | -0.0201269 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0199328 |
| TMEM41B | transmembrane protein 41B | -0.0198948 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0196337 |
| CDCP1 | CUB domain containing protein 1 | -0.0195674 |
| HDLBP | high density lipoprotein binding protein | -0.0195253 |
| RPLP1 | ribosomal protein, large, P1 | -0.0195044 |
| LAMB3 | laminin, beta 3 | -0.0194926 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0193757 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0193483 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0192959 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0192904 |
| NAV2 | neuron navigator 2 | -0.0192631 |
| RPL35A | ribosomal protein L35a | -0.0191458 |
| PRPF6 | pre-mRNA processing factor 6 | -0.0191368 |
| RPS19 | ribosomal protein S19 | -0.0190801 |
| RPL11 | ribosomal protein L11 | -0.0189884 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0189841 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0185826 |
| RNF213 | ring finger protein 213 | -0.0183119 |
| ZNF106 | zinc finger protein 106 | -0.0181697 |
| SERINC1 | serine incorporator 1 | -0.0178306 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0177951 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0177138 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0175839 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0174431 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0174428 |
| SNRK | SNF related kinase | -0.0173811 |
| CCPG1 | cell cycle progression 1 | -0.017246 |
