| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil (mesylate) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Belumosudil (mesylate)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.138648 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.12215 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0805299 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0772968 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0733361 |
| EGR1 | early growth response 1 | 0.0709698 |
| UBC | ubiquitin C | 0.0588786 |
| TXNIP | thioredoxin interacting protein | 0.0570434 |
| AREG | amphiregulin | 0.0567643 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0562841 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0536147 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0516302 |
| GOLGA4 | golgin A4 | 0.0504663 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0503904 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.050168 |
| RPS6 | ribosomal protein S6 | 0.0493612 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0467492 |
| RPL4 | ribosomal protein L4 | 0.0465793 |
| SGMS2 | sphingomyelin synthase 2 | 0.0457776 |
| ATXN1 | ataxin 1 | 0.0449418 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0443611 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0431497 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0427073 |
| RPL3 | ribosomal protein L3 | 0.0421566 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0393363 |
| RPS8 | ribosomal protein S8 | 0.0374363 |
| RPL21 | ribosomal protein L21 | 0.0370268 |
| CPOX | coproporphyrinogen oxidase | 0.0359895 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0342654 |
| BRD2 | bromodomain containing 2 | 0.0341679 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0338969 |
| EGFR | epidermal growth factor receptor | 0.0301501 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0291379 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.028286 |
| RPS2 | ribosomal protein S2 | 0.0275245 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0273738 |
| YAP1 | Yes-associated protein 1 | 0.0273278 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0272722 |
| RPS12 | ribosomal protein S12 | 0.0272181 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0270268 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0269858 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0258281 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0255169 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0248342 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0248104 |
| CENPF | centromere protein F, 350/400kDa | 0.0244254 |
| SNX9 | sorting nexin 9 | 0.0242738 |
| TES | testin LIM domain protein | 0.0239082 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0239051 |
| NKTR | natural killer cell triggering receptor | 0.0238545 |
| ANXA1 | annexin A1 | 0.0235258 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0232025 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.022925 |
| TOB2 | transducer of ERBB2, 2 | 0.0227887 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0225744 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0221773 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.022031 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0219757 |
| SEC24A | SEC24 family member A | 0.0217689 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0217384 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0217125 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0216897 |
| LIMA1 | LIM domain and actin binding 1 | 0.0214749 |
| ENO1 | enolase 1, (alpha) | 0.0208729 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0208426 |
| HDGF | hepatoma-derived growth factor | 0.0206329 |
| ARFGEF3 | ARFGEF family member 3 | 0.0202714 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0202658 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0202488 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0202106 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0200985 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0199875 |
| ZFP36 | ZFP36 ring finger protein | 0.01998 |
| DIAPH1 | diaphanous-related formin 1 | 0.0197577 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0196923 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.019497 |
| TPM3 | tropomyosin 3 | 0.0194611 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.019417 |
| RYBP | RING1 and YY1 binding protein | 0.0194022 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0192868 |
| PNN | pinin, desmosome associated protein | 0.0191873 |
| SON | SON DNA binding protein | 0.0190895 |
| SPAG9 | sperm associated antigen 9 | 0.0189137 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.018837 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0184978 |
| PCBP2 | poly(rC) binding protein 2 | 0.0183925 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0183752 |
| FAT1 | FAT atypical cadherin 1 | 0.0183252 |
| SLTM | SAFB-like, transcription modulator | 0.0182736 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0180371 |
| SESN2 | sestrin 2 | 0.0179834 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0179356 |
| VEGFA | vascular endothelial growth factor A | 0.0178312 |
| ARRDC4 | arrestin domain containing 4 | 0.017822 |
| IER2 | immediate early response 2 | 0.0178205 |
| NUP58 | nucleoporin 58 | 0.0177443 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0177222 |
| FAM120A | family with sequence similarity 120A | 0.0175312 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0173394 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0172839 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.287581 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.141542 |
| LAMB3 | laminin, beta 3 | -0.125342 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.106699 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.106028 |
| RPL35A | ribosomal protein L35a | -0.0826418 |
| TMSB10 | thymosin beta 10 | -0.0816219 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0780669 |
| HMGA2 | high mobility group AT-hook 2 | -0.0726016 |
| SERINC5 | serine incorporator 5 | -0.0691567 |
| ACTG1 | actin gamma 1 | -0.0682649 |
| HDAC2 | histone deacetylase 2 | -0.0636714 |
| FERMT1 | fermitin family member 1 | -0.0620608 |
| FHIT | fragile histidine triad | -0.0601082 |
| CUX1 | cut-like homeobox 1 | -0.0555903 |
| VCL | vinculin | -0.0553127 |
| ANXA2 | annexin A2 | -0.0534352 |
| RAD51B | RAD51 paralog B | -0.052312 |
| RPS24 | ribosomal protein S24 | -0.0511999 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0508479 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0505464 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0485253 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.046042 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0458115 |
| MTAP | methylthioadenosine phosphorylase | -0.0443201 |
| RPL34 | ribosomal protein L34 | -0.0393273 |
| RPS29 | ribosomal protein S29 | -0.0391258 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0388827 |
| DSPP | dentin sialophosphoprotein | -0.0388184 |
| UBE3C | ubiquitin protein ligase E3C | -0.0382395 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0381505 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0373946 |
| RCOR1 | REST corepressor 1 | -0.0362197 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0355091 |
| DENND1A | DENN/MADD domain containing 1A | -0.0353298 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0347502 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0346515 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0343266 |
| EZR | ezrin | -0.033285 |
| TPM4 | tropomyosin 4 | -0.0331768 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0328612 |
| CDK13 | cyclin-dependent kinase 13 | -0.0321371 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0318129 |
| EXOC4 | exocyst complex component 4 | -0.0314097 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.0312636 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0306526 |
| ZBTB7C | zinc finger and BTB domain containing 7C | -0.0302873 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0296322 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.029357 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0291382 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0291148 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0288688 |
| S100A6 | S100 calcium binding protein A6 | -0.0287774 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0285539 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0283779 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0272961 |
| SMYD3 | SET and MYND domain containing 3 | -0.0272782 |
| MDN1 | MDN1, midasin homolog (yeast) | -0.0266126 |
| RPL26 | ribosomal protein L26 | -0.0266098 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0265934 |
| IER3 | immediate early response 3 | -0.0265897 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0265733 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0259942 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | -0.0257716 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0256332 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.025631 |
| NT5DC3 | 5'-nucleotidase domain containing 3 | -0.0255414 |
| RTN3 | reticulon 3 | -0.0254503 |
| ACTN4 | actinin, alpha 4 | -0.0253067 |
| ARF1 | ADP-ribosylation factor 1 | -0.0252859 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0252016 |
| NPR2 | natriuretic peptide receptor 2 | -0.0251332 |
| APP | amyloid beta (A4) precursor protein | -0.0247959 |
| RPS15 | ribosomal protein S15 | -0.0247681 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0247659 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0247605 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0242833 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0240538 |
| RAB10 | RAB10, member RAS oncogene family | -0.0240298 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0238496 |
| SBF2 | SET binding factor 2 | -0.023833 |
| CD9 | CD9 molecule | -0.0235847 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0234938 |
| TNPO1 | transportin 1 | -0.0234834 |
| CCND1 | cyclin D1 | -0.0231959 |
| PTMA | prothymosin, alpha | -0.0231433 |
| CMIP | c-Maf inducing protein | -0.0231186 |
| KRT18 | keratin 18, type I | -0.0230393 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0227863 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0227473 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0227312 |
| BMP2K | BMP2 inducible kinase | -0.0222866 |
| PERP | PERP, TP53 apoptosis effector | -0.0220878 |
| RHEB | Ras homolog enriched in brain | -0.0220165 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0219964 |
| RPL38 | ribosomal protein L38 | -0.0219812 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.0219738 |
| ITGB4 | integrin, beta 4 | -0.0217233 |
| S100A11 | S100 calcium binding protein A11 | -0.0215917 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0215267 |
