| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belumosudil_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.232137 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.164548 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.112728 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0985255 |
| CDH13 | cadherin 13 | 0.0962991 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0908247 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0907701 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0905865 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0866159 |
| LOXL2 | lysyl oxidase-like 2 | 0.0842084 |
| AUTS2 | autism susceptibility candidate 2 | 0.0753207 |
| MT2A | metallothionein 2A | 0.0739271 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0698583 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0677897 |
| SLC39A11 | solute carrier family 39, member 11 | 0.064903 |
| SEPTIN9 | septin 9 | 0.0618881 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0604731 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0585859 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0567873 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0555316 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0541485 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0500166 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.048174 |
| FMNL2 | formin-like 2 | 0.0462513 |
| GPC6 | glypican 6 | 0.0458941 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0446012 |
| ADM | adrenomedullin | 0.0425631 |
| SQSTM1 | sequestosome 1 | 0.0406198 |
| RPL19 | ribosomal protein L19 | 0.0401391 |
| PLEC | plectin | 0.0381255 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0368629 |
| DTNA | dystrobrevin, alpha | 0.0348255 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0341523 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0341012 |
| RUNX1 | runt-related transcription factor 1 | 0.0334429 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.033182 |
| ATP13A3 | ATPase type 13A3 | 0.0325779 |
| VEGFA | vascular endothelial growth factor A | 0.0322901 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0320149 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0318754 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0316419 |
| CALD1 | caldesmon 1 | 0.0316264 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0314837 |
| EFNA5 | ephrin-A5 | 0.0314514 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0308077 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0306363 |
| MSN | moesin | 0.0305445 |
| MSI2 | musashi RNA-binding protein 2 | 0.0298647 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0298495 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0292069 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.0291356 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0291259 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0290912 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0283103 |
| MYOF | myoferlin | 0.0281325 |
| L1CAM | L1 cell adhesion molecule | 0.0281294 |
| TPM1 | tropomyosin 1 (alpha) | 0.0280069 |
| ZNF292 | zinc finger protein 292 | 0.0278312 |
| OPTN | optineurin | 0.0278143 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0276413 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0276276 |
| ANK2 | ankyrin 2, neuronal | 0.0269724 |
| RNF145 | ring finger protein 145 | 0.0269077 |
| SETD5 | SET domain containing 5 | 0.0268098 |
| ADAR | adenosine deaminase, RNA-specific | 0.0265743 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0264268 |
| SBF2 | SET binding factor 2 | 0.0262931 |
| DOCK9 | dedicator of cytokinesis 9 | 0.0257531 |
| DBN1 | drebrin 1 | 0.0256779 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0252584 |
| PGK1 | phosphoglycerate kinase 1 | 0.0252365 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0250796 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.0249893 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0247359 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0246427 |
| ARRDC3 | arrestin domain containing 3 | 0.0244727 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0242383 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0242195 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0240208 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0239856 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0239633 |
| ERBIN | erbb2 interacting protein | 0.0237597 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0236565 |
| PFKP | phosphofructokinase, platelet | 0.0236376 |
| RPS8 | ribosomal protein S8 | 0.0235551 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0231348 |
| RPS6 | ribosomal protein S6 | 0.0229728 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0229494 |
| SUCNR1 | succinate receptor 1 | 0.0227705 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0226806 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0226252 |
| NAV2 | neuron navigator 2 | 0.0222877 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0221769 |
| KIF13A | kinesin family member 13A | 0.0220747 |
| ITGA6 | integrin, alpha 6 | 0.0220739 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0219842 |
| PRELID2 | PRELI domain containing 2 | 0.0219389 |
| GANAB | glucosidase, alpha; neutral AB | 0.0219075 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0217175 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0215645 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LOX | lysyl oxidase | -0.299211 |
| UBC | ubiquitin C | -0.255539 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.221153 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.108925 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.102614 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.100849 |
| COL3A1 | collagen, type III, alpha 1 | -0.0965191 |
| TMSB10 | thymosin beta 10 | -0.0946096 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.093643 |
| LDHA | lactate dehydrogenase A | -0.0794159 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0734779 |
| COL1A2 | collagen, type I, alpha 2 | -0.0650902 |
| VIM | vimentin | -0.063977 |
| COL5A1 | collagen, type V, alpha 1 | -0.0627112 |
| LOC112694756 | uncharaterized LOC112694756 | -0.058943 |
| CALU | calumenin | -0.0576233 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0575876 |
| RPS27A | ribosomal protein S27a | -0.0528796 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0527827 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0511791 |
| PKM | pyruvate kinase, muscle | -0.0503095 |
| COL5A2 | collagen, type V, alpha 2 | -0.0490874 |
| CD99 | CD99 molecule | -0.0469956 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0469604 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0458811 |
| CAVIN1 | caveolae associated protein 1 | -0.0443717 |
| TPM4 | tropomyosin 4 | -0.0436827 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0429729 |
| SPAG9 | sperm associated antigen 9 | -0.0426988 |
| S100A6 | S100 calcium binding protein A6 | -0.0421173 |
| COPA | coatomer protein complex, subunit alpha | -0.0419662 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0417115 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.0413817 |
| TXNIP | thioredoxin interacting protein | -0.0399188 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0397068 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0396557 |
| LMNA | lamin A/C | -0.0384658 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0376131 |
| ENO1 | enolase 1, (alpha) | -0.0373439 |
| HLA-B | major histocompatibility complex, class I, B | -0.0357697 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0355398 |
| TAGLN2 | transgelin 2 | -0.0346845 |
| CLIC4 | chloride intracellular channel 4 | -0.0346479 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0344448 |
| MT1X | metallothionein 1X | -0.0340011 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0335508 |
| STC1 | stanniocalcin 1 | -0.0326216 |
| HDLBP | high density lipoprotein binding protein | -0.0326136 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0325508 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0323662 |
| ARF1 | ADP-ribosylation factor 1 | -0.0319935 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0319118 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.031899 |
| RTN4 | reticulon 4 | -0.0318285 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0311577 |
| AHNAK | AHNAK nucleoprotein | -0.030744 |
| NBEAL1 | neurobeachin-like 1 | -0.030707 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0306902 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0302519 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.02999 |
| SEC24D | SEC24 family member D | -0.029498 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0294455 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0291775 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0290969 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0284145 |
| MYADM | myeloid-associated differentiation marker | -0.0282672 |
| ZNF217 | zinc finger protein 217 | -0.0282416 |
| NSD3 | nuclear receptor binding SET domain protein 3 | -0.0282235 |
| HLA-E | major histocompatibility complex, class I, E | -0.0281655 |
| ANXA2 | annexin A2 | -0.0280014 |
| TMEM263 | transmembrane protein 263 | -0.0279694 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0278932 |
| TAPBP | TAP binding protein (tapasin) | -0.0276993 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0270087 |
| KIFAP3 | kinesin-associated protein 3 | -0.0268664 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0268621 |
| GLIS3 | GLIS family zinc finger 3 | -0.0264766 |
| TAOK1 | TAO kinase 1 | -0.0262963 |
| ZNF207 | zinc finger protein 207 | -0.0260638 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0252414 |
| MYO9B | myosin IXB | -0.0250472 |
| FBN1 | fibrillin 1 | -0.024888 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0248356 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0247331 |
| JUN | jun proto-oncogene | -0.024691 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0245998 |
| SUCO | SUN domain containing ossification factor | -0.0245822 |
| RBM25 | RNA binding motif protein 25 | -0.0245274 |
| CTSB | cathepsin B | -0.0244823 |
| GNAS | GNAS complex locus | -0.0243079 |
| FBXO11 | F-box protein 11 | -0.0242593 |
| THBS2 | thrombospondin 2 | -0.0240238 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0233704 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0233357 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) | -0.0231273 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0229196 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0224603 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0222722 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0220441 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0218972 |
