| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belumosudil_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.151622 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.104247 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0963891 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0962115 |
| MGAT4C | MGAT4 family, member C | 0.0931628 |
| PTMA | prothymosin, alpha | 0.0879955 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0837324 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.077005 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0723222 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0664328 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0636705 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0597268 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0576759 |
| MED13L | mediator complex subunit 13-like | 0.0574306 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0516545 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0511953 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0487084 |
| ANXA1 | annexin A1 | 0.0470087 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0467577 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0466422 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0464531 |
| AHNAK | AHNAK nucleoprotein | 0.0449003 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0432587 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0426026 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0424456 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0419558 |
| SET | SET nuclear proto-oncogene | 0.0414237 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0404286 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.040369 |
| NEK7 | NIMA-related kinase 7 | 0.0393763 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0387008 |
| ZNF292 | zinc finger protein 292 | 0.038125 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0376743 |
| TENM3 | teneurin transmembrane protein 3 | 0.0372201 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0369809 |
| LARP1 | La ribonucleoprotein domain family, member 1 | 0.0354727 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0349656 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0348512 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0347927 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0346773 |
| HDGF | hepatoma-derived growth factor | 0.0330936 |
| CDK17 | cyclin-dependent kinase 17 | 0.032735 |
| RPL19 | ribosomal protein L19 | 0.0325741 |
| MATR3 | matrin 3 | 0.0320414 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0319992 |
| AXIN2 | axin 2 | 0.0319253 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.031913 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0318754 |
| DSPP | dentin sialophosphoprotein | 0.0317321 |
| RNF145 | ring finger protein 145 | 0.0316927 |
| CALR | calreticulin | 0.0314329 |
| GASK1B | golgi associated kinase 1B | 0.0306916 |
| XPO1 | exportin 1 | 0.0300401 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0294047 |
| CCNY | cyclin Y | 0.0292539 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0289747 |
| CLDN1 | claudin 1 | 0.0286603 |
| RPL41 | ribosomal protein L41 | 0.0283642 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0279519 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0278455 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0277603 |
| WDR43 | WD repeat domain 43 | 0.0272299 |
| FMNL2 | formin-like 2 | 0.0271585 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0271091 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0266392 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0266074 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0264607 |
| THOC2 | THO complex 2 | 0.0263832 |
| CANX | calnexin | 0.0260227 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0259435 |
| GANAB | glucosidase, alpha; neutral AB | 0.0259229 |
| NCKAP1 | NCK-associated protein 1 | 0.0254353 |
| PLK2 | polo-like kinase 2 | 0.0253145 |
| MDN1 | MDN1, midasin homolog (yeast) | 0.0252384 |
| RPL14 | ribosomal protein L14 | 0.0248155 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0245464 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0245188 |
| PNN | pinin, desmosome associated protein | 0.0244883 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0242806 |
| FAT1 | FAT atypical cadherin 1 | 0.0241509 |
| TFG | TRK-fused gene | 0.0240243 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | 0.0239825 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0237393 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0235658 |
| RASAL2 | RAS protein activator like 2 | 0.0233401 |
| ENAH | enabled homolog (Drosophila) | 0.0230055 |
| CCDC47 | coiled-coil domain containing 47 | 0.0229964 |
| CARD16 | caspase recruitment domain family, member 16 | 0.02299 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0228577 |
| YTHDC1 | YTH domain containing 1 | 0.0228515 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0228254 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.0227925 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0227787 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | 0.0226687 |
| KIF5B | kinesin family member 5B | 0.0226269 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.022607 |
| RBM27 | RNA binding motif protein 27 | 0.0225202 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.022311 |
| SERINC1 | serine incorporator 1 | 0.0222949 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0221827 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.332524 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.188928 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0893269 |
| EGR1 | early growth response 1 | -0.0818477 |
| USP34 | ubiquitin specific peptidase 34 | -0.0806874 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0784631 |
| YAP1 | Yes-associated protein 1 | -0.0740127 |
| AREG | amphiregulin | -0.0724409 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0650281 |
| ACTG1 | actin gamma 1 | -0.063926 |
| JMJD1C | jumonji domain containing 1C | -0.0622834 |
| TMSB10 | thymosin beta 10 | -0.0620026 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0586988 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.05811 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.056469 |
| RPS2 | ribosomal protein S2 | -0.0562503 |
| TUBA1B | tubulin, alpha 1b | -0.0557969 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0551863 |
| VMP1 | vacuole membrane protein 1 | -0.0547377 |
| HMGA2 | high mobility group AT-hook 2 | -0.0544127 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0530432 |
| NABP1 | nucleic acid binding protein 1 | -0.0505605 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0491216 |
| CLTC | clathrin, heavy chain (Hc) | -0.0488975 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0487836 |
| ZNF804A | zinc finger protein 804A | -0.0483735 |
| BPTF | bromodomain PHD finger transcription factor | -0.0471352 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0458608 |
| CCND1 | cyclin D1 | -0.0436149 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0421084 |
| RTN4 | reticulon 4 | -0.0420853 |
| ZNF638 | zinc finger protein 638 | -0.0400123 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0396626 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0387011 |
| RRM2 | ribonucleotide reductase M2 | -0.0386018 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0383271 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0380525 |
| NF1 | neurofibromin 1 | -0.0379239 |
| FTL | ferritin, light polypeptide | -0.0379111 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0359814 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0351059 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0346178 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0337001 |
| MORF4L2 | mortality factor 4 like 2 | -0.0335457 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0334443 |
| SETX | senataxin | -0.033431 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0322697 |
| PCM1 | pericentriolar material 1 | -0.0319551 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0318272 |
| CCDC88A | coiled-coil domain containing 88A | -0.0316334 |
| MYPN | myopalladin | -0.0309503 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.030783 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0306767 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0305323 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0300537 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0297494 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0296131 |
| GOLGB1 | golgin B1 | -0.0295812 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.029565 |
| EDARADD | EDAR-associated death domain | -0.0292527 |
| RAD51B | RAD51 paralog B | -0.0292519 |
| ATXN2 | ataxin 2 | -0.0291618 |
| PCDH7 | protocadherin 7 | -0.029116 |
| HELLS | helicase, lymphoid-specific | -0.0289451 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0284194 |
| RAB10 | RAB10, member RAS oncogene family | -0.0283919 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0281574 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0281045 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.028089 |
| INTS6 | integrator complex subunit 6 | -0.0278161 |
| MMP12 | matrix metallopeptidase 12 | -0.0276774 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0274981 |
| RPS6 | ribosomal protein S6 | -0.0273746 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0272998 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0272463 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0270832 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0268529 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0267136 |
| CCN2 | cellular communication network factor 2 | -0.0265842 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0265342 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0264858 |
| RPLP1 | ribosomal protein, large, P1 | -0.0263331 |
| RANBP17 | RAN binding protein 17 | -0.026104 |
| ADIPOR2 | adiponectin receptor 2 | -0.0260285 |
| LRRC23 | leucine rich repeat containing 23 | -0.0259661 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0258906 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.0257837 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.025663 |
| ATP11A | ATPase, class VI, type 11A | -0.0253393 |
| PHF14 | PHD finger protein 14 | -0.0252869 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0249112 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0248795 |
| TMEM41B | transmembrane protein 41B | -0.0246139 |
| EFNA5 | ephrin-A5 | -0.0245985 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | -0.0245756 |
| ERBIN | erbb2 interacting protein | -0.024481 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0244538 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0243146 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0241163 |
| KIAA1328 | KIAA1328 | -0.0241127 |
