| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Belumosudil_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.183716 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.181063 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.111137 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.098786 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0751941 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.070166 |
| PTMA | prothymosin, alpha | 0.0691525 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0683257 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0665013 |
| RNF213 | ring finger protein 213 | 0.0663247 |
| LSAMP | limbic system-associated membrane protein | 0.0609253 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0607581 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0593737 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0587795 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.055876 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0526857 |
| FMN1 | formin 1 | 0.051272 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0507977 |
| CANX | calnexin | 0.0500007 |
| FAM13A | family with sequence similarity 13, member A | 0.0480854 |
| SEPTIN9 | septin 9 | 0.0471789 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0471622 |
| CENPF | centromere protein F, 350/400kDa | 0.0457953 |
| ITGA1 | integrin, alpha 1 | 0.0450031 |
| AHNAK | AHNAK nucleoprotein | 0.044222 |
| APP | amyloid beta (A4) precursor protein | 0.0429399 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0422216 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0418563 |
| YEATS2 | YEATS domain containing 2 | 0.041698 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0409119 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0400394 |
| DST | dystonin | 0.0394631 |
| KIAA1217 | KIAA1217 | 0.0387093 |
| AHR | aryl hydrocarbon receptor | 0.0385007 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0382985 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0382838 |
| SMYD3 | SET and MYND domain containing 3 | 0.0379839 |
| PTGES2 | prostaglandin E synthase 2 | 0.0379364 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0378263 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.037483 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0374116 |
| SP100 | SP100 nuclear antigen | 0.0372834 |
| MEF2A | myocyte enhancer factor 2A | 0.037246 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0370229 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0368022 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0362578 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0362576 |
| XPO1 | exportin 1 | 0.0361999 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0360632 |
| DPH6 | diphthamine biosynthesis 6 | 0.0359905 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0358918 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0357308 |
| TULP4 | tubby like protein 4 | 0.0348322 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.03474 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0345824 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0343832 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0343759 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0341429 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.033963 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0339104 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0338155 |
| CALR | calreticulin | 0.0336819 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0334273 |
| VGF | VGF nerve growth factor inducible | 0.0330872 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0329892 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0328738 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0325728 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0322139 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0320241 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.031447 |
| VIM | vimentin | 0.0309513 |
| VEGFA | vascular endothelial growth factor A | 0.0307139 |
| FNIP1 | folliculin interacting protein 1 | 0.0305265 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0302879 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.030239 |
| OGA | O-GlcNAcase | 0.0299441 |
| SMAD3 | SMAD family member 3 | 0.0298229 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.029789 |
| TPM4 | tropomyosin 4 | 0.0297658 |
| SETD2 | SET domain containing 2 | 0.0297061 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0293162 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0291215 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.0289783 |
| SYT1 | synaptotagmin I | 0.0289007 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0288012 |
| FAM162A | family with sequence similarity 162, member A | 0.0286644 |
| KIF5B | kinesin family member 5B | 0.0286407 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0285618 |
| ARRDC3 | arrestin domain containing 3 | 0.028551 |
| ANKRD36 | ankyrin repeat domain 36 | 0.02837 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0283652 |
| DNMBP | dynamin binding protein | 0.0282827 |
| ZNF207 | zinc finger protein 207 | 0.0281456 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0278812 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0274413 |
| TPR | translocated promoter region, nuclear basket protein | 0.027437 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0270479 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0268764 |
| YTHDC1 | YTH domain containing 1 | 0.0265749 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0265444 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.410446 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.215091 |
| MAP1B | microtubule-associated protein 1B | -0.0842065 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.075067 |
| MEIS2 | Meis homeobox 2 | -0.071668 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0712127 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.062803 |
| COL1A1 | collagen, type I, alpha 1 | -0.06244 |
| DTNA | dystrobrevin, alpha | -0.0581372 |
| ACTG1 | actin gamma 1 | -0.0448216 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0392701 |
| NF1 | neurofibromin 1 | -0.0375216 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0362295 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0361978 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0361971 |
| PTEN | phosphatase and tensin homolog | -0.0352357 |
| MED13 | mediator complex subunit 13 | -0.0352026 |
| VCL | vinculin | -0.034824 |
| TMSB10 | thymosin beta 10 | -0.0347318 |
| POTEF | POTE ankyrin domain family, member F | -0.0338319 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.032664 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0320249 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0308619 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0303777 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0303646 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0300015 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0297377 |
| IER3 | immediate early response 3 | -0.0294457 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0291763 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0287762 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.0286897 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.0285817 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0285351 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0282957 |
| LRRC7 | leucine rich repeat containing 7 | -0.0282175 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0280857 |
| KLHL13 | kelch-like family member 13 | -0.0280034 |
| HMBOX1 | homeobox containing 1 | -0.0274001 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0270835 |
| CDK12 | cyclin-dependent kinase 12 | -0.0268864 |
| ANGPT1 | angiopoietin 1 | -0.0266458 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0265719 |
| CLTC | clathrin, heavy chain (Hc) | -0.0262497 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0259217 |
| HMGB1 | high mobility group box 1 | -0.0259067 |
| RPL35A | ribosomal protein L35a | -0.0258057 |
| LPIN1 | lipin 1 | -0.0257142 |
| CXXC5 | CXXC finger protein 5 | -0.0256639 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0256479 |
| RBM25 | RNA binding motif protein 25 | -0.0253129 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0252457 |
| RIC1 | RAB6A GEF complex partner 1 | -0.0248603 |
| DSTN | destrin (actin depolymerizing factor) | -0.0247989 |
| MMP2 | matrix metallopeptidase 2 | -0.0241898 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | -0.024015 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.0239273 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0237041 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0236494 |
| HMGA1 | high mobility group AT-hook 1 | -0.0236293 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0233604 |
| GNAS | GNAS complex locus | -0.0233144 |
| JAM3 | junctional adhesion molecule 3 | -0.0232545 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0232199 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0231272 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0228158 |
| RPS24 | ribosomal protein S24 | -0.0227649 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.022722 |
| BPTF | bromodomain PHD finger transcription factor | -0.0226236 |
| RPL13A | ribosomal protein L13a | -0.0224624 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0224363 |
| FBXO34 | F-box protein 34 | -0.0224247 |
| RPS21 | ribosomal protein S21 | -0.0223244 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | -0.0222883 |
| THBS1 | thrombospondin 1 | -0.0222016 |
| GRB2 | growth factor receptor-bound protein 2 | -0.0221892 |
| LDHB | lactate dehydrogenase B | -0.0221627 |
| LMNA | lamin A/C | -0.0217493 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.0217006 |
| GATA3 | GATA binding protein 3 | -0.0216868 |
| ACLY | ATP citrate lyase | -0.0216766 |
| ZFP36 | ZFP36 ring finger protein | -0.0213719 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0213225 |
| SIK2 | salt-inducible kinase 2 | -0.0212986 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0212219 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0211944 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0211628 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0211338 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0210688 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0210505 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0206848 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D | -0.0205661 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0204799 |
| SEC24D | SEC24 family member D | -0.0203412 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0203268 |
| QKI | QKI, KH domain containing, RNA binding | -0.0203158 |
| PHOX2B | paired-like homeobox 2b | -0.0202838 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.020131 |
| RPS19 | ribosomal protein S19 | -0.0201265 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) | -0.0201061 |
| PFN1 | profilin 1 | -0.0200118 |
