| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belumosudil_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0894567 |
| CANX | calnexin | 0.0876667 |
| PTMA | prothymosin, alpha | 0.0869929 |
| CALR | calreticulin | 0.083636 |
| RPL19 | ribosomal protein L19 | 0.0816363 |
| ARGLU1 | arginine and glutamate rich 1 | 0.076201 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.072136 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0634883 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0616974 |
| RNF149 | ring finger protein 149 | 0.0541531 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0541437 |
| MLPH | melanophilin | 0.0539373 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.051574 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0503701 |
| ASPH | aspartate beta-hydroxylase | 0.0479411 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0473911 |
| GOLGB1 | golgin B1 | 0.0457648 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0456809 |
| APOL1 | apolipoprotein L, 1 | 0.0456486 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0453165 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0396696 |
| KIF16B | kinesin family member 16B | 0.0387206 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0386606 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0383969 |
| ENO1 | enolase 1, (alpha) | 0.0377563 |
| ERCC5 | excision repair cross-complementation group 5 | 0.03754 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0357016 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0352337 |
| AHNAK | AHNAK nucleoprotein | 0.0334198 |
| DSPP | dentin sialophosphoprotein | 0.0331333 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0323817 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0322124 |
| AHI1 | Abelson helper integration site 1 | 0.0315828 |
| HYOU1 | hypoxia up-regulated 1 | 0.0300141 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0299325 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0295189 |
| OGA | O-GlcNAcase | 0.0293904 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0293453 |
| KRT19 | keratin 19, type I | 0.0293124 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0289436 |
| PFKP | phosphofructokinase, platelet | 0.0287078 |
| GOLGA2 | golgin A2 | 0.0284405 |
| LASP1 | LIM and SH3 protein 1 | 0.0283272 |
| TMSB4X | thymosin beta 4, X-linked | 0.0282263 |
| FDPS | farnesyl diphosphate synthase | 0.0279142 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0278917 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0271735 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0269639 |
| CHD3 | chromodomain helicase DNA binding protein 3 | 0.026941 |
| HLA-E | major histocompatibility complex, class I, E | 0.0265241 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0262509 |
| STYXL2 | serine/threonine/tyrosine interacting like 2 | 0.02601 |
| PTGR1 | prostaglandin reductase 1 | 0.0258725 |
| APOL2 | apolipoprotein L, 2 | 0.0256655 |
| RBM26 | RNA binding motif protein 26 | 0.0255982 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0254733 |
| NPSR1 | neuropeptide S receptor 1 | 0.0254511 |
| ANXA4 | annexin A4 | 0.0254006 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | 0.0253533 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0252644 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0249511 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0247775 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 0.024413 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0244041 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0243375 |
| RPL7L1 | ribosomal protein L7-like 1 | 0.0241471 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0241262 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0241194 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0237472 |
| FAT1 | FAT atypical cadherin 1 | 0.023397 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0225163 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0224563 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0224264 |
| CMIP | c-Maf inducing protein | 0.0223881 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0223185 |
| MYO10 | myosin X | 0.0222045 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.022161 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0216914 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0216056 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.0214165 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0213711 |
| RSRP1 | arginine/serine-rich protein 1 | 0.0211217 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0207348 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0206641 |
| RFLNA | refilin A | 0.0205947 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.020486 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0203287 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0202253 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0201525 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0201468 |
| TPM3 | tropomyosin 3 | 0.0201104 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0199113 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0199091 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0197438 |
| NDRG1 | N-myc downstream regulated 1 | 0.0196908 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.019666 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0193723 |
| SET | SET nuclear proto-oncogene | 0.0190862 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0190667 |
| PLIN2 | perilipin 2 | 0.0190131 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGR1 | early growth response 1 | -0.176787 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.167457 |
| LMO7 | LIM domain 7 | -0.144423 |
| MYO1E | myosin IE | -0.133703 |
| ANXA2 | annexin A2 | -0.106519 |
| LCN2 | lipocalin 2 | -0.101689 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0996887 |
| EZR | ezrin | -0.0919214 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0914639 |
| IRF1 | interferon regulatory factor 1 | -0.0895325 |
| B2M | beta-2-microglobulin | -0.0890093 |
| CCNL1 | cyclin L1 | -0.0864965 |
| VCL | vinculin | -0.0828972 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0787918 |
| VMP1 | vacuole membrane protein 1 | -0.0760409 |
| ERBIN | erbb2 interacting protein | -0.0760141 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0751988 |
| AREG | amphiregulin | -0.0729391 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0696 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0694611 |
| TJP1 | tight junction protein 1 | -0.0682742 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0681168 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0670711 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0664167 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.06537 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0645786 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.060025 |
| RUNX1 | runt-related transcription factor 1 | -0.0591594 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0581735 |
| STK24 | serine/threonine kinase 24 | -0.0581547 |
| CLDN4 | claudin 4 | -0.0576897 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0566751 |
| JUN | jun proto-oncogene | -0.0561905 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0555377 |
| NCKAP5 | NCK-associated protein 5 | -0.0519437 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0519398 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0505792 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0497239 |
| PLSCR1 | phospholipid scramblase 1 | -0.0479478 |
| RIGI | RNA sensor RIG-I | -0.0479299 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0475042 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0469185 |
| PERP | PERP, TP53 apoptosis effector | -0.0462217 |
| MUC13 | mucin 13, cell surface associated | -0.0461233 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0459469 |
| MX2 | MX dynamin-like GTPase 2 | -0.0456024 |
| POTEF | POTE ankyrin domain family, member F | -0.0453586 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0452354 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0451247 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0447027 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.04432 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0440861 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0433855 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0426663 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0425824 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0418312 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0417007 |
| CST3 | cystatin C | -0.0400768 |
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | -0.0399683 |
| BPTF | bromodomain PHD finger transcription factor | -0.0398848 |
| SQSTM1 | sequestosome 1 | -0.0397775 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0390604 |
| SDC4 | syndecan 4 | -0.038736 |
| NEBL | nebulette | -0.0384985 |
| INTS6 | integrator complex subunit 6 | -0.0383932 |
| FUS | FUS RNA binding protein | -0.0376974 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0375707 |
| EFNB2 | ephrin-B2 | -0.03694 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0360995 |
| ACTG1 | actin gamma 1 | -0.0359372 |
| FTL | ferritin, light polypeptide | -0.0358043 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0357782 |
| SP100 | SP100 nuclear antigen | -0.0356102 |
| IRS2 | insulin receptor substrate 2 | -0.0353392 |
| KIAA1217 | KIAA1217 | -0.0343978 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0339558 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0338931 |
| RPL35A | ribosomal protein L35a | -0.0337256 |
| ZNF207 | zinc finger protein 207 | -0.0330574 |
| MEIS2 | Meis homeobox 2 | -0.0329606 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0327578 |
| CALU | calumenin | -0.0324769 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0324419 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0322965 |
| TMC5 | transmembrane channel-like 5 | -0.0319019 |
| FOSL1 | FOS-like antigen 1 | -0.0315281 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0302711 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0302542 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | -0.0301808 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0300429 |
| TC2N | tandem C2 domains, nuclear | -0.0300415 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0296839 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0295583 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0295102 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0294488 |
| BRD2 | bromodomain containing 2 | -0.0292929 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0292849 |
| TRIM25 | tripartite motif containing 25 | -0.0291785 |
| HLA-B | major histocompatibility complex, class I, B | -0.0290698 |
| MAP7 | microtubule-associated protein 7 | -0.0289996 |
