| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belumosudil_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.201313 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.199464 |
| COL6A3 | collagen, type VI, alpha 3 | 0.19345 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.16434 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.121841 |
| VIM | vimentin | 0.106664 |
| LOXL2 | lysyl oxidase-like 2 | 0.0958603 |
| ATP13A3 | ATPase type 13A3 | 0.0918099 |
| CADM1 | cell adhesion molecule 1 | 0.0849977 |
| MT2A | metallothionein 2A | 0.0791327 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.078319 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0747099 |
| POSTN | periostin, osteoblast specific factor | 0.0739735 |
| ENO1 | enolase 1, (alpha) | 0.0726694 |
| NDRG1 | N-myc downstream regulated 1 | 0.0718782 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0710763 |
| CALR | calreticulin | 0.0703308 |
| RPL19 | ribosomal protein L19 | 0.0677842 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0666588 |
| ARRDC3 | arrestin domain containing 3 | 0.0653451 |
| VEGFA | vascular endothelial growth factor A | 0.0652802 |
| SMAD3 | SMAD family member 3 | 0.0651501 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0650028 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0647882 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0646351 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0624675 |
| RPL7 | ribosomal protein L7 | 0.0615373 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0603916 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0556093 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0544703 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0539906 |
| PLEC | plectin | 0.0529282 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0520815 |
| FMNL2 | formin-like 2 | 0.0510971 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0498377 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0497583 |
| MYO10 | myosin X | 0.049196 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0478751 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0476396 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0475856 |
| ANKRD11 | ankyrin repeat domain 11 | 0.046506 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.046035 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0459961 |
| ZNF292 | zinc finger protein 292 | 0.0455009 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0446609 |
| CANX | calnexin | 0.043813 |
| PTK2 | protein tyrosine kinase 2 | 0.0436825 |
| PTMA | prothymosin, alpha | 0.0430634 |
| NAV2 | neuron navigator 2 | 0.0426043 |
| MSN | moesin | 0.0422873 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0409211 |
| INHBA | inhibin, beta A | 0.0404341 |
| RASA2 | RAS p21 protein activator 2 | 0.0401237 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0399794 |
| FLNA | filamin A, alpha | 0.0395935 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0388067 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0374009 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0372284 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0372121 |
| TMSB4X | thymosin beta 4, X-linked | 0.0364763 |
| RPS8 | ribosomal protein S8 | 0.0350938 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0340498 |
| RPL3 | ribosomal protein L3 | 0.0338906 |
| VCAN | versican | 0.0338082 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0336562 |
| RPL11 | ribosomal protein L11 | 0.033082 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0328961 |
| PRELID2 | PRELI domain containing 2 | 0.0321074 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0318305 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0311216 |
| RPS12 | ribosomal protein S12 | 0.0309472 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0306821 |
| YBX1 | Y box binding protein 1 | 0.0301208 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0294764 |
| ADM | adrenomedullin | 0.0292201 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0291554 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0291261 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0285954 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0282663 |
| RPL23 | ribosomal protein L23 | 0.0277581 |
| CCNY | cyclin Y | 0.0270765 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0269523 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0265293 |
| SEPTIN9 | septin 9 | 0.0264272 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0262147 |
| TPM2 | tropomyosin 2 (beta) | 0.025705 |
| ANXA5 | annexin A5 | 0.0255662 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0255469 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0255193 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.025177 |
| APP | amyloid beta (A4) precursor protein | 0.0251736 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0249909 |
| ZNF148 | zinc finger protein 148 | 0.0249819 |
| RUNX1 | runt-related transcription factor 1 | 0.0247981 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0247557 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0246182 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0245389 |
| IRF1 | interferon regulatory factor 1 | 0.0245361 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.024306 |
| RNF145 | ring finger protein 145 | 0.0241888 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.407387 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.162914 |
| COL1A1 | collagen, type I, alpha 1 | -0.158878 |
| LOX | lysyl oxidase | -0.116472 |
| HMGA2 | high mobility group AT-hook 2 | -0.0772259 |
| FN1 | fibronectin 1 | -0.0642931 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0592355 |
| GLIS3 | GLIS family zinc finger 3 | -0.0585207 |
| FBN1 | fibrillin 1 | -0.0549619 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0484404 |
| EGR1 | early growth response 1 | -0.0469078 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0439384 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0436424 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0416019 |
| HLA-B | major histocompatibility complex, class I, B | -0.0414699 |
| PALLD | palladin, cytoskeletal associated protein | -0.039076 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0380692 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0367361 |
| TMSB10 | thymosin beta 10 | -0.0362256 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0342445 |
| OSMR | oncostatin M receptor | -0.0333464 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0315312 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0313847 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0302343 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0296722 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0286331 |
| COL1A2 | collagen, type I, alpha 2 | -0.0285711 |
| HM13 | histocompatibility (minor) 13 | -0.0281015 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0260756 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0260226 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.025869 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0254322 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0252682 |
| TAPBP | TAP binding protein (tapasin) | -0.0251278 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0247382 |
| RRBP1 | ribosome binding protein 1 | -0.0246825 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0244494 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0243622 |
| NABP1 | nucleic acid binding protein 1 | -0.0235976 |
| VCL | vinculin | -0.0235398 |
| FTL | ferritin, light polypeptide | -0.0231837 |
| IER3 | immediate early response 3 | -0.0230387 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0227802 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0219683 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0218932 |
| ATM | ATM serine/threonine kinase | -0.0217859 |
| INTS6 | integrator complex subunit 6 | -0.0217598 |
| CALU | calumenin | -0.0217406 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0210832 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0210007 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0209675 |
| SEC24A | SEC24 family member A | -0.0206203 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0205272 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0205267 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0198926 |
| SEC24D | SEC24 family member D | -0.0195682 |
| EHD2 | EH-domain containing 2 | -0.0193331 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0192755 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0188957 |
| ARF4 | ADP-ribosylation factor 4 | -0.0188755 |
| NREP | neuronal regeneration related protein | -0.0186187 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0186028 |
| TMEM263 | transmembrane protein 263 | -0.0185731 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0180654 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0180256 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0177787 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0175533 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0175467 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0174041 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0173723 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0172794 |
| CLTC | clathrin, heavy chain (Hc) | -0.017063 |
| AHI1 | Abelson helper integration site 1 | -0.0168659 |
| BPTF | bromodomain PHD finger transcription factor | -0.0167651 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.016656 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0164737 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0164702 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0164661 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0164334 |
| MT1X | metallothionein 1X | -0.0163922 |
| ZNF644 | zinc finger protein 644 | -0.0163065 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0162646 |
| PRR16 | proline rich 16 | -0.0157041 |
| CD44 | CD44 molecule (Indian blood group) | -0.0154732 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0153714 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0153489 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0152845 |
| NSD3 | nuclear receptor binding SET domain protein 3 | -0.0151711 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.0151531 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.015027 |
| RSU1 | Ras suppressor protein 1 | -0.0150165 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0148715 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0148537 |
| FBXO11 | F-box protein 11 | -0.0146485 |
| RBPMS | RNA binding protein with multiple splicing | -0.0146111 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0145439 |
| MORF4L2 | mortality factor 4 like 2 | -0.0145367 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.014531 |
| NLRP1 | NLR family, pyrin domain containing 1 | -0.0145169 |
| ARF1 | ADP-ribosylation factor 1 | -0.0144783 |
