| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Belumosudil_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.293695 |
| PLEC | plectin | 0.124656 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.119865 |
| KRT17 | keratin 17, type I | 0.109069 |
| RPL19 | ribosomal protein L19 | 0.106231 |
| TMSB4X | thymosin beta 4, X-linked | 0.104787 |
| ACTN4 | actinin, alpha 4 | 0.0920881 |
| CALR | calreticulin | 0.0856911 |
| PTMA | prothymosin, alpha | 0.0838234 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0826507 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0752928 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0747987 |
| KRT6A | keratin 6A, type II | 0.07184 |
| FLNA | filamin A, alpha | 0.0662796 |
| TMSB10 | thymosin beta 10 | 0.0655169 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0643327 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0636508 |
| CD9 | CD9 molecule | 0.0625222 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0616104 |
| MYO10 | myosin X | 0.0550117 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0547489 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0534835 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0533865 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0522898 |
| TPM3 | tropomyosin 3 | 0.0521438 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0518436 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0515872 |
| CANX | calnexin | 0.0487424 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0484899 |
| ITGB4 | integrin, beta 4 | 0.0479277 |
| BLCAP | bladder cancer associated protein | 0.0479174 |
| ENO1 | enolase 1, (alpha) | 0.0475522 |
| LOXL2 | lysyl oxidase-like 2 | 0.0466235 |
| ITGA6 | integrin, alpha 6 | 0.044961 |
| PDLIM1 | PDZ and LIM domain 1 | 0.0447756 |
| PGK1 | phosphoglycerate kinase 1 | 0.0439942 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0429086 |
| NDRG1 | N-myc downstream regulated 1 | 0.0428724 |
| EPHA2 | EPH receptor A2 | 0.0428247 |
| PYGL | phosphorylase, glycogen, liver | 0.0426713 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0422851 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0418271 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0416363 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.041006 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0399577 |
| KRT14 | keratin 14, type I | 0.0390707 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.0384209 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0380908 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0376244 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0375957 |
| SULF1 | sulfatase 1 | 0.0370009 |
| DUSP6 | dual specificity phosphatase 6 | 0.03658 |
| CEP250 | centrosomal protein 250kDa | 0.0365198 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0365169 |
| LMNA | lamin A/C | 0.0364732 |
| LIMA1 | LIM domain and actin binding 1 | 0.0364452 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0359534 |
| ANGPTL4 | angiopoietin-like 4 | 0.0359153 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0354346 |
| KRT19 | keratin 19, type I | 0.0353168 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.0351116 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.034701 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0344815 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0343023 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0339006 |
| NCOR2 | nuclear receptor corepressor 2 | 0.033672 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0336506 |
| YBX1 | Y box binding protein 1 | 0.0333901 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.033367 |
| MCL1 | myeloid cell leukemia 1 | 0.0330834 |
| MSN | moesin | 0.0325274 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0323307 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0322893 |
| DSPP | dentin sialophosphoprotein | 0.0320231 |
| CAVIN1 | caveolae associated protein 1 | 0.0311894 |
| RIN2 | Ras and Rab interactor 2 | 0.0311099 |
| HLA-E | major histocompatibility complex, class I, E | 0.0306261 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0303794 |
| TAGLN2 | transgelin 2 | 0.0302748 |
| RAI14 | retinoic acid induced 14 | 0.0302552 |
| RALGDS | ral guanine nucleotide dissociation stimulator | 0.0301743 |
| S100A2 | S100 calcium binding protein A2 | 0.0297572 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.0293642 |
| DHFR | dihydrofolate reductase | 0.0293627 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.0292828 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0286074 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.028567 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0285522 |
| KRT18 | keratin 18, type I | 0.0285198 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0284057 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0283018 |
| PRELID2 | PRELI domain containing 2 | 0.0280105 |
| EMP1 | epithelial membrane protein 1 | 0.027797 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0277748 |
| AMOTL1 | angiomotin like 1 | 0.0276135 |
| BCL2L1 | BCL2-like 1 | 0.0275193 |
| S100A10 | S100 calcium binding protein A10 | 0.0274671 |
| PRSS23 | protease, serine, 23 | 0.0273721 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0272332 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.026277 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.221712 |
| INTS6 | integrator complex subunit 6 | -0.102349 |
| MTSS1 | metastasis suppressor 1 | -0.0847587 |
| CLU | clusterin | -0.0847202 |
| RBM39 | RNA binding motif protein 39 | -0.0842924 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0727335 |
| RPS13 | ribosomal protein S13 | -0.0633242 |
| KIAA1217 | KIAA1217 | -0.0594608 |
| JMJD1C | jumonji domain containing 1C | -0.0572519 |
| MEF2A | myocyte enhancer factor 2A | -0.0570911 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0546268 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0510177 |
| FTL | ferritin, light polypeptide | -0.0500821 |
| RPS21 | ribosomal protein S21 | -0.0499643 |
| CD44 | CD44 molecule (Indian blood group) | -0.0462963 |
| RPS2 | ribosomal protein S2 | -0.0458888 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0458851 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0427371 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0418132 |
| CLIC4 | chloride intracellular channel 4 | -0.0416509 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0411245 |
| HLA-B | major histocompatibility complex, class I, B | -0.0410152 |
| RPS6 | ribosomal protein S6 | -0.0405548 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0377868 |
| SQSTM1 | sequestosome 1 | -0.0377855 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0374905 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0373003 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.036947 |
| NF1 | neurofibromin 1 | -0.0364633 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0357508 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0356927 |
| FOXO1 | forkhead box O1 | -0.0355522 |
| SPAG9 | sperm associated antigen 9 | -0.035413 |
| UBC | ubiquitin C | -0.0347245 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0339502 |
| FUS | FUS RNA binding protein | -0.0335587 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0333386 |
| DOK5 | docking protein 5 | -0.0330668 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0329235 |
| MT1E | metallothionein 1E | -0.0329057 |
| ANKRD10 | ankyrin repeat domain 10 | -0.032735 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0323775 |
| LDLR | low density lipoprotein receptor | -0.0320914 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0319026 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0318739 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.031779 |
| POTEF | POTE ankyrin domain family, member F | -0.031655 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0313533 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0313061 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.031228 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0311896 |
| FNIP1 | folliculin interacting protein 1 | -0.0311262 |
| PTK2 | protein tyrosine kinase 2 | -0.0310596 |
| H1-0 | H1.0 linker histone | -0.0304802 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0303356 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0302935 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0302109 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0300906 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0300702 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0298014 |
| CDK13 | cyclin-dependent kinase 13 | -0.0292783 |
| SUCO | SUN domain containing ossification factor | -0.0292068 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0288703 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.02873 |
| RPL38 | ribosomal protein L38 | -0.0282229 |
| TSPAN3 | tetraspanin 3 | -0.028132 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0278926 |
| COPA | coatomer protein complex, subunit alpha | -0.0276167 |
| RB1 | retinoblastoma 1 | -0.0275954 |
| MORF4L2 | mortality factor 4 like 2 | -0.0274862 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.027394 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0273926 |
| HM13 | histocompatibility (minor) 13 | -0.0269378 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0267559 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0266735 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0266596 |
| CALU | calumenin | -0.0263312 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.026266 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0261337 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0261193 |
| EGR1 | early growth response 1 | -0.0260077 |
| PMM2 | phosphomannomutase 2 | -0.0259357 |
| MAP4 | microtubule-associated protein 4 | -0.0258588 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0258243 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0257517 |
| RPL28 | ribosomal protein L28 | -0.0257315 |
| ZNF217 | zinc finger protein 217 | -0.0256689 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0256079 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0256051 |
| NKTR | natural killer cell triggering receptor | -0.0255887 |
| CUL4B | cullin 4B | -0.0255259 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0253911 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0253625 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0252364 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0251193 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0248746 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0248114 |
| RPS23 | ribosomal protein S23 | -0.0246263 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0245627 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.024539 |
