| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belumosudil_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | 0.247832 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.171296 |
| FNDC3B | fibronectin type III domain containing 3B | 0.13851 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.126866 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.113689 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.107769 |
| DSPP | dentin sialophosphoprotein | 0.0994056 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0991318 |
| HYOU1 | hypoxia up-regulated 1 | 0.0976924 |
| AHNAK | AHNAK nucleoprotein | 0.0973383 |
| PLEC | plectin | 0.0958899 |
| MUC17 | mucin 17, cell surface associated | 0.094283 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0920058 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0840558 |
| CANX | calnexin | 0.0762541 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0750977 |
| GOLGB1 | golgin B1 | 0.0699266 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0696713 |
| KRT18 | keratin 18, type I | 0.0677883 |
| PTMA | prothymosin, alpha | 0.0616751 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0615831 |
| SNX9 | sorting nexin 9 | 0.0587502 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0578321 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0572662 |
| CALR | calreticulin | 0.0539961 |
| KRT17 | keratin 17, type I | 0.0522521 |
| ZNF292 | zinc finger protein 292 | 0.0503988 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0496904 |
| ACTG1 | actin gamma 1 | 0.0481247 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0471598 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0464347 |
| FLNB | filamin B, beta | 0.0458128 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0448277 |
| TES | testin LIM domain protein | 0.0433471 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.043177 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0423659 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0417643 |
| SLK | STE20-like kinase | 0.0415275 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0405703 |
| ITGA6 | integrin, alpha 6 | 0.0402317 |
| MYO5B | myosin VB | 0.039535 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.039504 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0386122 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0381381 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0381315 |
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.0380618 |
| LAMB3 | laminin, beta 3 | 0.037594 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0375063 |
| SMAD3 | SMAD family member 3 | 0.0374451 |
| ACTN4 | actinin, alpha 4 | 0.0373052 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0365942 |
| AFDN | afadin, adherens junction formation factor | 0.0364023 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0360935 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.035018 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.034903 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0347922 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0344494 |
| ARCN1 | archain 1 | 0.0343171 |
| SET | SET nuclear proto-oncogene | 0.0342302 |
| OGA | O-GlcNAcase | 0.0341159 |
| HKDC1 | hexokinase domain containing 1 | 0.0336982 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0334464 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0332983 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0331318 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0329628 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0327556 |
| CCDC47 | coiled-coil domain containing 47 | 0.0325742 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0322659 |
| NDRG1 | N-myc downstream regulated 1 | 0.0322365 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0321856 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.032013 |
| GANAB | glucosidase, alpha; neutral AB | 0.0315744 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0315699 |
| MYO6 | myosin VI | 0.0315156 |
| RNF213 | ring finger protein 213 | 0.0304947 |
| RPL19 | ribosomal protein L19 | 0.0301304 |
| ANKRD11 | ankyrin repeat domain 11 | 0.030101 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0300573 |
| SQSTM1 | sequestosome 1 | 0.0294262 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0292286 |
| SLTM | SAFB-like, transcription modulator | 0.0290949 |
| RNF145 | ring finger protein 145 | 0.0288057 |
| GOLGA4 | golgin A4 | 0.0287576 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0286956 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0286761 |
| MYOF | myoferlin | 0.0285975 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.028561 |
| PTK2 | protein tyrosine kinase 2 | 0.0284977 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0283158 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0282352 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0281858 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0279004 |
| VEGFA | vascular endothelial growth factor A | 0.0276336 |
| TPM3 | tropomyosin 3 | 0.0274259 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0274238 |
| NEK6 | NIMA-related kinase 6 | 0.027323 |
| CTTN | cortactin | 0.0272072 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0271725 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.0271464 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0264745 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.163157 |
| TMSB10 | thymosin beta 10 | -0.146266 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.136829 |
| NPSR1 | neuropeptide S receptor 1 | -0.107498 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0948494 |
| FTL | ferritin, light polypeptide | -0.0875418 |
| RPL35A | ribosomal protein L35a | -0.0783764 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0681995 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0675163 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0618146 |
| RPLP1 | ribosomal protein, large, P1 | -0.060832 |
| S100A10 | S100 calcium binding protein A10 | -0.0586581 |
| B2M | beta-2-microglobulin | -0.0570018 |
| AGR2 | anterior gradient 2 | -0.0558121 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0541487 |
| PKM | pyruvate kinase, muscle | -0.0517174 |
| S100A6 | S100 calcium binding protein A6 | -0.0515418 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0507353 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0495239 |
| WDR45B | WD repeat domain 45B | -0.0485366 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0484217 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0479527 |
| CLDN7 | claudin 7 | -0.0477234 |
| KRT8 | keratin 8, type II | -0.0458726 |
| GPX2 | glutathione peroxidase 2 | -0.0451456 |
| RPS21 | ribosomal protein S21 | -0.0445306 |
| TXNIP | thioredoxin interacting protein | -0.0443806 |
| RPS19 | ribosomal protein S19 | -0.0431136 |
| EPCAM | epithelial cell adhesion molecule | -0.0428056 |
| INSIG1 | insulin induced gene 1 | -0.0426523 |
| EGR1 | early growth response 1 | -0.0419606 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0412623 |
| S100P | S100 calcium binding protein P | -0.0402539 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0393669 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0392966 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0391491 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0380842 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0374924 |
| ATF5 | activating transcription factor 5 | -0.0367536 |
| RPS6 | ribosomal protein S6 | -0.0362237 |
| POTEF | POTE ankyrin domain family, member F | -0.0361873 |
| RPL28 | ribosomal protein L28 | -0.0354368 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0351975 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0344583 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.033575 |
| RPS24 | ribosomal protein S24 | -0.0333942 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.032959 |
| TMC5 | transmembrane channel-like 5 | -0.0320715 |
| CLDN4 | claudin 4 | -0.0320015 |
| ATP11A | ATPase, class VI, type 11A | -0.03181 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.030994 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0306805 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0305579 |
| PHF14 | PHD finger protein 14 | -0.0304334 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0299364 |
| PFN1 | profilin 1 | -0.0298834 |
| RPL30 | ribosomal protein L30 | -0.0294564 |
| NF1 | neurofibromin 1 | -0.0284797 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0283601 |
| NFIB | nuclear factor I/B | -0.0280958 |
| PRSS3 | protease, serine, 3 | -0.0279222 |
| CST3 | cystatin C | -0.0276781 |
| LCN2 | lipocalin 2 | -0.0269726 |
| S100A9 | S100 calcium binding protein A9 | -0.0269088 |
| HLA-B | major histocompatibility complex, class I, B | -0.0263552 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0263193 |
| HMGB1 | high mobility group box 1 | -0.026193 |
| GNAS | GNAS complex locus | -0.0261824 |
| MECOM | MDS1 and EVI1 complex locus | -0.0261797 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0261212 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0260787 |
| TMEM45B | transmembrane protein 45B | -0.0259642 |
| MCU | mitochondrial calcium uniporter | -0.0258652 |
| CDK6 | cyclin-dependent kinase 6 | -0.0257539 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0257307 |
| MUC1 | mucin 1, cell surface associated | -0.0252187 |
| NBEAL1 | neurobeachin-like 1 | -0.0250882 |
| ATF4 | activating transcription factor 4 | -0.0248803 |
| MORF4L2 | mortality factor 4 like 2 | -0.0248467 |
| RPL39 | ribosomal protein L39 | -0.0247574 |
| ALDOC | aldolase C, fructose-bisphosphate | -0.0246687 |
| PRKCA | protein kinase C, alpha | -0.0246637 |
| MEIS2 | Meis homeobox 2 | -0.0242803 |
| RPS16 | ribosomal protein S16 | -0.0242321 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.02418 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0240236 |
| MSI2 | musashi RNA-binding protein 2 | -0.023952 |
| ASTN2 | astrotactin 2 | -0.0236561 |
| TMEM123 | transmembrane protein 123 | -0.0236164 |
| EHBP1 | EH domain binding protein 1 | -0.0233025 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | -0.0231903 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0231888 |
| CCDC146 | coiled-coil domain containing 146 | -0.0230899 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0230369 |
| VDAC1 | voltage-dependent anion channel 1 | -0.02294 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0228602 |
| NFIA | nuclear factor I/A | -0.0224922 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0224291 |
| BPTF | bromodomain PHD finger transcription factor | -0.022374 |
| RPS25 | ribosomal protein S25 | -0.022234 |
