| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belumosudil_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.167463 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.129384 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.120805 |
| PTMA | prothymosin, alpha | 0.077229 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0764463 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0721984 |
| KRT18 | keratin 18, type I | 0.0708054 |
| FAM13A | family with sequence similarity 13, member A | 0.0706505 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0683877 |
| ITGA6 | integrin, alpha 6 | 0.0679721 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0672162 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0664737 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0610966 |
| FLNB | filamin B, beta | 0.0588741 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0580335 |
| NDRG1 | N-myc downstream regulated 1 | 0.0575845 |
| DSPP | dentin sialophosphoprotein | 0.056479 |
| AHNAK | AHNAK nucleoprotein | 0.0560715 |
| RREB1 | ras responsive element binding protein 1 | 0.0556466 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0548415 |
| KRT8 | keratin 8, type II | 0.05413 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0511583 |
| MUC17 | mucin 17, cell surface associated | 0.0495178 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0492167 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0490947 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0485057 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0476521 |
| FAT1 | FAT atypical cadherin 1 | 0.0457508 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.044889 |
| ACTN4 | actinin, alpha 4 | 0.0439474 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0435472 |
| PLEC | plectin | 0.0425849 |
| CCNY | cyclin Y | 0.0404313 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0404246 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.039524 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0391957 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0391906 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0390379 |
| TMSB4X | thymosin beta 4, X-linked | 0.0389781 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0384756 |
| SLK | STE20-like kinase | 0.0381139 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0373178 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0370611 |
| RPL3 | ribosomal protein L3 | 0.0366541 |
| RPL13A | ribosomal protein L13a | 0.0365231 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0353074 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0348661 |
| TPM3 | tropomyosin 3 | 0.0347988 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0340706 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0335483 |
| YTHDC1 | YTH domain containing 1 | 0.0329609 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0327114 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0322085 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0310164 |
| RNF145 | ring finger protein 145 | 0.0307573 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0303025 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0300452 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.029756 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0297364 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0295592 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0294961 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0293214 |
| SET | SET nuclear proto-oncogene | 0.0290949 |
| XPO1 | exportin 1 | 0.0287426 |
| EHF | ets homologous factor | 0.0284754 |
| EMP1 | epithelial membrane protein 1 | 0.0280913 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0279853 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0279577 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0276377 |
| SLTM | SAFB-like, transcription modulator | 0.0276239 |
| RPL14 | ribosomal protein L14 | 0.027588 |
| ZNF292 | zinc finger protein 292 | 0.0266268 |
| CALR | calreticulin | 0.026437 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.0262743 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0262218 |
| MATR3 | matrin 3 | 0.0258017 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0256869 |
| PCBP2 | poly(rC) binding protein 2 | 0.0256862 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.025406 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0250058 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0249986 |
| CANX | calnexin | 0.0249786 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0249514 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0248438 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0246634 |
| YME1L1 | YME1-like 1 ATPase | 0.0245659 |
| HDGF | hepatoma-derived growth factor | 0.0242827 |
| ANXA1 | annexin A1 | 0.024226 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0237493 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0237212 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0234497 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0234195 |
| ENO1 | enolase 1, (alpha) | 0.0233008 |
| KIF5B | kinesin family member 5B | 0.0231855 |
| MYOF | myoferlin | 0.0230916 |
| EPHA2 | EPH receptor A2 | 0.0230164 |
| VEGFA | vascular endothelial growth factor A | 0.0225675 |
| PGK1 | phosphoglycerate kinase 1 | 0.0224883 |
| GANAB | glucosidase, alpha; neutral AB | 0.0223671 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0223385 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.353016 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0994407 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0856035 |
| RPS2 | ribosomal protein S2 | -0.0710664 |
| TXNIP | thioredoxin interacting protein | -0.0692787 |
| RPS6 | ribosomal protein S6 | -0.0686484 |
| MYO1E | myosin IE | -0.0621434 |
| RPLP1 | ribosomal protein, large, P1 | -0.0523999 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0516577 |
| GPHN | gephyrin | -0.0486741 |
| PKM | pyruvate kinase, muscle | -0.0484199 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0452853 |
| TMSB10 | thymosin beta 10 | -0.04476 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0419952 |
| MED13 | mediator complex subunit 13 | -0.0416041 |
| PATJ | PATJ crumbs cell polarity complex component | -0.041253 |
| EPCAM | epithelial cell adhesion molecule | -0.0408771 |
| CLTC | clathrin, heavy chain (Hc) | -0.0400235 |
| FTL | ferritin, light polypeptide | -0.0399244 |
| PTEN | phosphatase and tensin homolog | -0.0388155 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0359886 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0358382 |
| TNS4 | tensin 4 | -0.035646 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.035572 |
| CADPS | Ca++-dependent secretion activator | -0.035276 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0338383 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0330247 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0330121 |
| ATXN1 | ataxin 1 | -0.0329141 |
| MT2A | metallothionein 2A | -0.0327107 |
| LDHA | lactate dehydrogenase A | -0.0316516 |
| EGR1 | early growth response 1 | -0.0315762 |
| RPLP0 | ribosomal protein, large, P0 | -0.0314994 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0306666 |
| TRIM2 | tripartite motif containing 2 | -0.0299571 |
| PRSS3 | protease, serine, 3 | -0.029795 |
| DSG2 | desmoglein 2 | -0.0297113 |
| RPS19 | ribosomal protein S19 | -0.029474 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0294464 |
| NF1 | neurofibromin 1 | -0.0291997 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0291924 |
| MT1X | metallothionein 1X | -0.0286788 |
| RPS21 | ribosomal protein S21 | -0.028677 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.028181 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.027944 |
| POF1B | premature ovarian failure, 1B | -0.0277468 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0276787 |
| RPL35A | ribosomal protein L35a | -0.0273449 |
| GOLGA4 | golgin A4 | -0.0273346 |
| RPS5 | ribosomal protein S5 | -0.0257861 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0257806 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0256314 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0251759 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0250116 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0247636 |
| ASTN2 | astrotactin 2 | -0.0247217 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0246355 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0241215 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0240706 |
| TMEM45B | transmembrane protein 45B | -0.0240368 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.023911 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0238854 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0238748 |
| RPLP2 | ribosomal protein, large, P2 | -0.0236594 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0236037 |
| TAOK1 | TAO kinase 1 | -0.0235729 |
| VMP1 | vacuole membrane protein 1 | -0.0235106 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0234662 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0231746 |
| KIAA2026 | KIAA2026 | -0.0231709 |
| USP34 | ubiquitin specific peptidase 34 | -0.0230133 |
| RPS8 | ribosomal protein S8 | -0.0229866 |
| RPS13 | ribosomal protein S13 | -0.0229663 |
| AGR2 | anterior gradient 2 | -0.0228989 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0227403 |
| FHL2 | four and a half LIM domains 2 | -0.0226427 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0224622 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0223279 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0223222 |
| SBF2 | SET binding factor 2 | -0.0222823 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0222261 |
| RPS16 | ribosomal protein S16 | -0.0222199 |
| ZNF91 | zinc finger protein 91 | -0.0220133 |
| METTL15 | methyltransferase like 15 | -0.0219942 |
| RPS24 | ribosomal protein S24 | -0.0218951 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0216107 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0215997 |
| SMYD3 | SET and MYND domain containing 3 | -0.0213035 |
| BRD2 | bromodomain containing 2 | -0.0210803 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0209826 |
| SETD5 | SET domain containing 5 | -0.0208655 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0206571 |
| PLS1 | plastin 1 | -0.0204564 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.020406 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0204048 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0202816 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0202003 |
| RTN3 | reticulon 3 | -0.0200622 |
| RPL7A | ribosomal protein L7a | -0.0199256 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0198389 |
