| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Belumosudil_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.169082 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.136936 |
| DST | dystonin | 0.120769 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.108554 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.107864 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.089673 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0856398 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0766289 |
| SET | SET nuclear proto-oncogene | 0.0705673 |
| AHNAK | AHNAK nucleoprotein | 0.0651679 |
| RPS8 | ribosomal protein S8 | 0.0577488 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0553295 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0537546 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0532855 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0505058 |
| ENO1 | enolase 1, (alpha) | 0.0503116 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0501053 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0500541 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0495333 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0484153 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0477415 |
| PTMA | prothymosin, alpha | 0.0477404 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0474661 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.046657 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0444093 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.044045 |
| FMNL2 | formin-like 2 | 0.0431699 |
| TPM3 | tropomyosin 3 | 0.0428025 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0421988 |
| SLK | STE20-like kinase | 0.0418258 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.041253 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0410386 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0410097 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0406878 |
| CENPF | centromere protein F, 350/400kDa | 0.0405939 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0395193 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.039409 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0389563 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0378056 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0375661 |
| RPL3 | ribosomal protein L3 | 0.0369754 |
| RPS3 | ribosomal protein S3 | 0.0354695 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0353918 |
| MATR3 | matrin 3 | 0.035085 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0347996 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0342946 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0338207 |
| DOCK11 | dedicator of cytokinesis 11 | 0.032981 |
| RPL26 | ribosomal protein L26 | 0.0326981 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0324137 |
| EREG | epiregulin | 0.0323707 |
| ANXA1 | annexin A1 | 0.0323411 |
| RPL11 | ribosomal protein L11 | 0.0316298 |
| XPO1 | exportin 1 | 0.031564 |
| CANX | calnexin | 0.0311767 |
| RPS12 | ribosomal protein S12 | 0.0309084 |
| HDGF | hepatoma-derived growth factor | 0.0307645 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0306548 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0306222 |
| RPL23 | ribosomal protein L23 | 0.0305418 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0303421 |
| PRELID2 | PRELI domain containing 2 | 0.0302265 |
| RPL37A | ribosomal protein L37a | 0.0301806 |
| RPL14 | ribosomal protein L14 | 0.0298731 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0298405 |
| ZNF292 | zinc finger protein 292 | 0.0288643 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0287602 |
| MYOF | myoferlin | 0.0286169 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0285282 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0283347 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0278733 |
| PLK2 | polo-like kinase 2 | 0.0278577 |
| YEATS2 | YEATS domain containing 2 | 0.0276261 |
| RBM25 | RNA binding motif protein 25 | 0.0275384 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0273649 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0273618 |
| RPL7 | ribosomal protein L7 | 0.0270918 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0268367 |
| MKI67 | marker of proliferation Ki-67 | 0.026808 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0264994 |
| PNN | pinin, desmosome associated protein | 0.0264066 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0262503 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0252465 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0250437 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0250041 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0248053 |
| TPR | translocated promoter region, nuclear basket protein | 0.0247825 |
| RPL19 | ribosomal protein L19 | 0.024631 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0245642 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0245625 |
| CAPRIN2 | caprin family member 2 | 0.0245585 |
| OGA | O-GlcNAcase | 0.0245201 |
| WDR43 | WD repeat domain 43 | 0.0242577 |
| RBM39 | RNA binding motif protein 39 | 0.0242042 |
| PLEC | plectin | 0.0241197 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0240802 |
| CCDC47 | coiled-coil domain containing 47 | 0.0239671 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0239645 |
| FUS | FUS RNA binding protein | 0.0237344 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0237042 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.333729 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0918564 |
| TMSB10 | thymosin beta 10 | -0.0838679 |
| MT1X | metallothionein 1X | -0.0783778 |
| EGR1 | early growth response 1 | -0.074798 |
| ACTG1 | actin gamma 1 | -0.0725494 |
| TP63 | tumor protein p63 | -0.071658 |
| MT2A | metallothionein 2A | -0.0621131 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0597076 |
| TXNRD1 | thioredoxin reductase 1 | -0.0559882 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0537585 |
| TXNIP | thioredoxin interacting protein | -0.0508472 |
| RUNX1 | runt-related transcription factor 1 | -0.0454558 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0445473 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0440018 |
| POTEF | POTE ankyrin domain family, member F | -0.0415214 |
| FBXO11 | F-box protein 11 | -0.0395221 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0386838 |
| VIM | vimentin | -0.0381292 |
| FTL | ferritin, light polypeptide | -0.0366015 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0365878 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0356998 |
| LDHA | lactate dehydrogenase A | -0.0354345 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0347979 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0327783 |
| RPL35A | ribosomal protein L35a | -0.031553 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0311488 |
| MT1E | metallothionein 1E | -0.0304789 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0301519 |
| HMGA1 | high mobility group AT-hook 1 | -0.0297311 |
| CD44 | CD44 molecule (Indian blood group) | -0.0285705 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.028111 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0280825 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0266599 |
| TMEM41B | transmembrane protein 41B | -0.0262952 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0260969 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0260736 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.025277 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0251477 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.0249728 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0242653 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0234379 |
| NF1 | neurofibromin 1 | -0.0232895 |
| RIGI | RNA sensor RIG-I | -0.0231953 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0230493 |
| RPLP1 | ribosomal protein, large, P1 | -0.0229812 |
| PLSCR1 | phospholipid scramblase 1 | -0.0229786 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.0224276 |
| ARF1 | ADP-ribosylation factor 1 | -0.0222431 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0221235 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0217297 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0214853 |
| S100A6 | S100 calcium binding protein A6 | -0.021484 |
| BSG | basigin (Ok blood group) | -0.0208177 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0203883 |
| SP100 | SP100 nuclear antigen | -0.0203634 |
| MORF4L2 | mortality factor 4 like 2 | -0.0200643 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0200337 |
| TAPBP | TAP binding protein (tapasin) | -0.0200132 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0198794 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0196402 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0194343 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0189085 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0188384 |
| WDR45B | WD repeat domain 45B | -0.0186879 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0184005 |
| HLA-B | major histocompatibility complex, class I, B | -0.0183692 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.018266 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0182625 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0181223 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0180546 |
| HPCAL1 | hippocalcin-like 1 | -0.0180088 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0178739 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0175579 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0169569 |
| SEC24A | SEC24 family member A | -0.0168952 |
| RPLP0 | ribosomal protein, large, P0 | -0.0168014 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0165802 |
| OSMR | oncostatin M receptor | -0.0165644 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0164802 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0163828 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0161527 |
| RGS4 | regulator of G-protein signaling 4 | -0.0160645 |
| JMJD1C | jumonji domain containing 1C | -0.015873 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0155828 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.015491 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0154402 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0152805 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0151085 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0148638 |
| TAOK1 | TAO kinase 1 | -0.0147273 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.014721 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0147081 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0146991 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0146786 |
| SCFD1 | sec1 family domain containing 1 | -0.0145922 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0145459 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0144289 |
| ARMC9 | armadillo repeat containing 9 | -0.014395 |
| VMP1 | vacuole membrane protein 1 | -0.0143565 |
