| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belumosudil_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.199543 |
| SMAD3 | SMAD family member 3 | 0.105505 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.104123 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0945267 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0851727 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0851509 |
| PCBP2 | poly(rC) binding protein 2 | 0.0829338 |
| PTMA | prothymosin, alpha | 0.0798811 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0719418 |
| OGA | O-GlcNAcase | 0.0665345 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0618931 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0605202 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0563767 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0553675 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0546476 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0523608 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0521668 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0507547 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0499751 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0492482 |
| VIM | vimentin | 0.049247 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0489227 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0482693 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0480531 |
| CALR | calreticulin | 0.0480361 |
| CANX | calnexin | 0.0467091 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0455711 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0437597 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0429903 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0421034 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0410479 |
| RPL19 | ribosomal protein L19 | 0.0401038 |
| FAM13A | family with sequence similarity 13, member A | 0.0388676 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0374155 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0372069 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0368406 |
| MT2A | metallothionein 2A | 0.0364182 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0358166 |
| PARD3 | par-3 family cell polarity regulator | 0.0355129 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0353326 |
| RNF145 | ring finger protein 145 | 0.0344195 |
| TXNRD1 | thioredoxin reductase 1 | 0.0343551 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0335469 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0329996 |
| SET | SET nuclear proto-oncogene | 0.0328706 |
| KYNU | kynureninase | 0.0316512 |
| PRELID2 | PRELI domain containing 2 | 0.0313079 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0311707 |
| YBX1 | Y box binding protein 1 | 0.0309686 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0307734 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0306399 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0302015 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0300399 |
| KIF5B | kinesin family member 5B | 0.0296211 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0296073 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0293127 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0292299 |
| MYO10 | myosin X | 0.0288611 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0288225 |
| USP3 | ubiquitin specific peptidase 3 | 0.0286603 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0286377 |
| YTHDC1 | YTH domain containing 1 | 0.0279684 |
| APP | amyloid beta (A4) precursor protein | 0.0279545 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0275894 |
| ADD3 | adducin 3 (gamma) | 0.0274736 |
| MYOF | myoferlin | 0.0270595 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0266736 |
| ATP13A3 | ATPase type 13A3 | 0.0263346 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0263244 |
| RPS12 | ribosomal protein S12 | 0.026049 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0259945 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0257113 |
| GPHN | gephyrin | 0.025268 |
| AHNAK | AHNAK nucleoprotein | 0.0251964 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0251271 |
| ANXA1 | annexin A1 | 0.0249843 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0249657 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0247655 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0244827 |
| ASPH | aspartate beta-hydroxylase | 0.0242493 |
| XPO1 | exportin 1 | 0.024237 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0241982 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.02413 |
| RPL23 | ribosomal protein L23 | 0.0240934 |
| PHIP | pleckstrin homology domain interacting protein | 0.024059 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0237316 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0237173 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0236778 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0234599 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0234211 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0233731 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0233297 |
| ARRDC3 | arrestin domain containing 3 | 0.0232621 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0230695 |
| RBM25 | RNA binding motif protein 25 | 0.022932 |
| ECE1 | endothelin converting enzyme 1 | 0.0228566 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0228485 |
| RPLP2 | ribosomal protein, large, P2 | 0.0227652 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0226713 |
| RPL9 | ribosomal protein L9 | 0.0226471 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.124815 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.121785 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.11952 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.11203 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.109056 |
| LOX | lysyl oxidase | -0.1078 |
| MEF2A | myocyte enhancer factor 2A | -0.10291 |
| CDH13 | cadherin 13 | -0.0970726 |
| FN1 | fibronectin 1 | -0.0887712 |
| NRG1 | neuregulin 1 | -0.0805354 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0802972 |
| MTSS1 | metastasis suppressor 1 | -0.0799658 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0792176 |
| STC1 | stanniocalcin 1 | -0.0778208 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0762935 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0721646 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0642347 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0620696 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0619003 |
| GRB10 | growth factor receptor-bound protein 10 | -0.060518 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0601719 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0560488 |
| EGR1 | early growth response 1 | -0.054344 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0526844 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0524385 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0510067 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0498892 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0492758 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0489689 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0485003 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0471999 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0455301 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0452642 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.044346 |
| IL1B | interleukin 1, beta | -0.0430133 |
| FBN1 | fibrillin 1 | -0.0419861 |
| NDRG1 | N-myc downstream regulated 1 | -0.0418171 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0407395 |
| RAI14 | retinoic acid induced 14 | -0.0404284 |
| TMEM165 | transmembrane protein 165 | -0.0403222 |
| CLMP | CXADR-like membrane protein | -0.0399366 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0398032 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0380002 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0376467 |
| SNX9 | sorting nexin 9 | -0.0373223 |
| DTNA | dystrobrevin, alpha | -0.0360322 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0359385 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0357366 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.035664 |
| CLIC4 | chloride intracellular channel 4 | -0.0350556 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0341324 |
| HM13 | histocompatibility (minor) 13 | -0.033978 |
| CA12 | carbonic anhydrase XII | -0.0337207 |
| CALU | calumenin | -0.0334873 |
| LRRC8C | leucine rich repeat containing 8 family, member C | -0.033202 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.032928 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0328209 |
| RND3 | Rho family GTPase 3 | -0.0322003 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0318029 |
| CCDC88A | coiled-coil domain containing 88A | -0.031631 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0315902 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0312564 |
| DENND4A | DENN/MADD domain containing 4A | -0.0310589 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.030024 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.029996 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0297415 |
| PYGL | phosphorylase, glycogen, liver | -0.0295303 |
| SEC24A | SEC24 family member A | -0.0293696 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0289229 |
| MYADM | myeloid-associated differentiation marker | -0.0283886 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0283273 |
| CDK14 | cyclin-dependent kinase 14 | -0.0281162 |
| NLRP1 | NLR family, pyrin domain containing 1 | -0.0276385 |
| HMGA2 | high mobility group AT-hook 2 | -0.0275474 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0275119 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0273744 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0273228 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0272118 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0268809 |
| OSMR | oncostatin M receptor | -0.0264545 |
| SLC44A5 | solute carrier family 44, member 5 | -0.0264238 |
| FNIP1 | folliculin interacting protein 1 | -0.0263664 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.026157 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0255515 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0254357 |
| SYNJ2 | synaptojanin 2 | -0.0249975 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0247895 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0247179 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0244993 |
| DNER | delta/notch-like EGF repeat containing | -0.0244225 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0243444 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0243428 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0243129 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0240375 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0240324 |
| BMERB1 | bMERB domain containing 1 | -0.0239759 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0238609 |
| ENOSF1 | enolase superfamily member 1 | -0.0233718 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0231718 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0231146 |
