| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belumosudil_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.155979 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.148435 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.144905 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.142395 |
| PTMA | prothymosin, alpha | 0.121176 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.11437 |
| TMSB4X | thymosin beta 4, X-linked | 0.112365 |
| HDAC9 | histone deacetylase 9 | 0.102704 |
| RPL19 | ribosomal protein L19 | 0.0971601 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0954893 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0857039 |
| AHNAK | AHNAK nucleoprotein | 0.0853434 |
| VCL | vinculin | 0.0823518 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0787354 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0786368 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0752192 |
| RPL3 | ribosomal protein L3 | 0.071833 |
| FLNB | filamin B, beta | 0.0710979 |
| CALR | calreticulin | 0.0707461 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0674669 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0626761 |
| EZR | ezrin | 0.0616659 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0614552 |
| PCBP2 | poly(rC) binding protein 2 | 0.0603769 |
| PYGB | phosphorylase, glycogen; brain | 0.0592062 |
| RPL11 | ribosomal protein L11 | 0.0587531 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0582944 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0572586 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0538168 |
| SET | SET nuclear proto-oncogene | 0.0528804 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0528085 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.052259 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0513978 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0509376 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0498039 |
| EGFR | epidermal growth factor receptor | 0.0492228 |
| CANX | calnexin | 0.0483118 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0480024 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.047758 |
| HSPA8 | heat shock 70kDa protein 8 | 0.044393 |
| FHIT | fragile histidine triad | 0.0441808 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0438053 |
| ANK2 | ankyrin 2, neuronal | 0.0429236 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0428466 |
| HDGF | hepatoma-derived growth factor | 0.0425978 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0425428 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0421255 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0419194 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0416931 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0414969 |
| RPL7 | ribosomal protein L7 | 0.0413044 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0409581 |
| TJP1 | tight junction protein 1 | 0.0406003 |
| LOXL3 | lysyl oxidase-like 3 | 0.0400474 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0397232 |
| ZNF292 | zinc finger protein 292 | 0.0396516 |
| APP | amyloid beta (A4) precursor protein | 0.0393091 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0393003 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0389796 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0387716 |
| PDGFC | platelet derived growth factor C | 0.0379008 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0372271 |
| ENO1 | enolase 1, (alpha) | 0.0370434 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0367453 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0361034 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0354573 |
| GANAB | glucosidase, alpha; neutral AB | 0.034104 |
| ITGA6 | integrin, alpha 6 | 0.0340789 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0338176 |
| OGA | O-GlcNAcase | 0.0336956 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0332197 |
| CD47 | CD47 molecule | 0.0331993 |
| CCNL1 | cyclin L1 | 0.0331158 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0331057 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0329626 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0328585 |
| ASPH | aspartate beta-hydroxylase | 0.0325777 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.032189 |
| YTHDC1 | YTH domain containing 1 | 0.031712 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0315129 |
| FBLN2 | fibulin 2 | 0.031311 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0310915 |
| CTBP2 | C-terminal binding protein 2 | 0.0304999 |
| PNN | pinin, desmosome associated protein | 0.0301857 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.029876 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0296257 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0296224 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0296185 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0295958 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0295725 |
| CENPF | centromere protein F, 350/400kDa | 0.0294823 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0294511 |
| RNF145 | ring finger protein 145 | 0.0294411 |
| RPS8 | ribosomal protein S8 | 0.0291657 |
| RPL21 | ribosomal protein L21 | 0.0289953 |
| GOLGA4 | golgin A4 | 0.0287741 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0287641 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0283774 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0282647 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0282623 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.31695 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0956787 |
| ACTG1 | actin gamma 1 | -0.0942763 |
| CCND1 | cyclin D1 | -0.0829621 |
| RPL35A | ribosomal protein L35a | -0.0591465 |
| BMP10 | bone morphogenetic protein 10 | -0.0551886 |
| PKM | pyruvate kinase, muscle | -0.0545001 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0544016 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0535518 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0492333 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.048489 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0459446 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0453939 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0447552 |
| RPS6 | ribosomal protein S6 | -0.0436706 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0427248 |
| POTEF | POTE ankyrin domain family, member F | -0.0409962 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0388027 |
| RPLP1 | ribosomal protein, large, P1 | -0.0381025 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0356078 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0342163 |
| LDHA | lactate dehydrogenase A | -0.0323507 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0319534 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0314944 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0309964 |
| RPS13 | ribosomal protein S13 | -0.029621 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0291605 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.029097 |
| GPATCH8 | G patch domain containing 8 | -0.0289955 |
| DIAPH3 | diaphanous-related formin 3 | -0.0286152 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0281997 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0280719 |
| S100A4 | S100 calcium binding protein A4 | -0.0279619 |
| RPS24 | ribosomal protein S24 | -0.027595 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0272388 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0261738 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0254546 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0253694 |
| ZNF608 | zinc finger protein 608 | -0.024777 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0247588 |
| FBXO11 | F-box protein 11 | -0.0244341 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0240137 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0237744 |
| RPL27A | ribosomal protein L27a | -0.0233154 |
| INTS6 | integrator complex subunit 6 | -0.022912 |
| FER1L6 | fer-1-like family member 6 | -0.0226903 |
| ECT2 | epithelial cell transforming 2 | -0.0225716 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0221004 |
| SPRY2 | sprouty homolog 2 (Drosophila) | -0.0218553 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0214808 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0214791 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0214588 |
| RPLP0 | ribosomal protein, large, P0 | -0.0210523 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0210501 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0206635 |
| THBD | thrombomodulin | -0.0206082 |
| CCNH | cyclin H | -0.0205619 |
| WDR45B | WD repeat domain 45B | -0.0203124 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.0202614 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0201806 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0201699 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0199909 |
| SP100 | SP100 nuclear antigen | -0.019979 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0199608 |
| ARHGAP25 | Rho GTPase activating protein 25 | -0.0197871 |
| TAOK1 | TAO kinase 1 | -0.0196117 |
| CDK14 | cyclin-dependent kinase 14 | -0.0194971 |
| PRKCI | protein kinase C, iota | -0.0194772 |
| TBCA | tubulin folding cofactor A | -0.0194398 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0194124 |
| KLF6 | Kruppel-like factor 6 | -0.0193264 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0191474 |
| LRRC58 | leucine rich repeat containing 58 | -0.0190662 |
| MYO5C | myosin VC | -0.0190627 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.018979 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0189307 |
| TUBA1B | tubulin, alpha 1b | -0.0185556 |
| BMP2K | BMP2 inducible kinase | -0.018345 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0183297 |
| GPATCH2L | G patch domain containing 2-like | -0.0180513 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0177654 |
| KIAA1328 | KIAA1328 | -0.0176914 |
| RPS23 | ribosomal protein S23 | -0.0176767 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0175242 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0175222 |
| RPS27A | ribosomal protein S27a | -0.0174868 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0173494 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0173339 |
| MLIP | muscular LMNA-interacting protein | -0.0173179 |
| CCDC138 | coiled-coil domain containing 138 | -0.0171933 |
| RTN3 | reticulon 3 | -0.0171654 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.017016 |
| SSH2 | slingshot protein phosphatase 2 | -0.0169389 |
| ARF1 | ADP-ribosylation factor 1 | -0.0168301 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0168299 |
| ZNF217 | zinc finger protein 217 | -0.0168004 |
| RPS2 | ribosomal protein S2 | -0.0166486 |
| MBTD1 | mbt domain containing 1 | -0.016606 |
| CORIN | corin, serine peptidase | -0.016567 |
| CCSER2 | coiled-coil serine-rich protein 2 | -0.0164891 |
