| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Belumosudil_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.27587 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.131711 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.128834 |
| THBS1 | thrombospondin 1 | 0.119449 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.111367 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.107969 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.10577 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.101981 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0994538 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0971244 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0922163 |
| AHNAK | AHNAK nucleoprotein | 0.0915118 |
| DST | dystonin | 0.0899782 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.088327 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0865881 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0847968 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0771898 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0769359 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0766364 |
| PTMA | prothymosin, alpha | 0.0750908 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0701005 |
| ADM | adrenomedullin | 0.069944 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.068716 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0671609 |
| CADM1 | cell adhesion molecule 1 | 0.0642473 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0616391 |
| CALR | calreticulin | 0.0608568 |
| VCAN | versican | 0.0603287 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0596729 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.057324 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0569793 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.05472 |
| ZNF292 | zinc finger protein 292 | 0.0530248 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0509309 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0503543 |
| CDH13 | cadherin 13 | 0.050177 |
| NAV2 | neuron navigator 2 | 0.049789 |
| CANX | calnexin | 0.049616 |
| OGA | O-GlcNAcase | 0.0495003 |
| CEP250 | centrosomal protein 250kDa | 0.0491417 |
| MKI67 | marker of proliferation Ki-67 | 0.0489275 |
| SRGN | serglycin | 0.0488526 |
| ATP13A3 | ATPase type 13A3 | 0.0486943 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0485201 |
| CD44 | CD44 molecule (Indian blood group) | 0.0480849 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.047778 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0475566 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0465469 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0454799 |
| TPM4 | tropomyosin 4 | 0.0440673 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0431607 |
| INHBA | inhibin, beta A | 0.0430014 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0426154 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0424054 |
| IER3 | immediate early response 3 | 0.0415228 |
| SET | SET nuclear proto-oncogene | 0.0408971 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0406916 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0397572 |
| ENO1 | enolase 1, (alpha) | 0.0393345 |
| PHF3 | PHD finger protein 3 | 0.0392355 |
| FMNL2 | formin-like 2 | 0.0391077 |
| SQSTM1 | sequestosome 1 | 0.0388285 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0387383 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0383181 |
| POTEF | POTE ankyrin domain family, member F | 0.0382356 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0381353 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0378052 |
| WTAP | Wilms tumor 1 associated protein | 0.0377937 |
| QKI | QKI, KH domain containing, RNA binding | 0.0376896 |
| ANLN | anillin, actin binding protein | 0.0373523 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0361471 |
| TNPO1 | transportin 1 | 0.0357897 |
| RPL14 | ribosomal protein L14 | 0.0354682 |
| CCBE1 | collagen and calcium binding EGF domains 1 | 0.0354032 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0341516 |
| MLPH | melanophilin | 0.0339382 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0337985 |
| TPM1 | tropomyosin 1 (alpha) | 0.033079 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0330325 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0327578 |
| RPS8 | ribosomal protein S8 | 0.0323637 |
| AFDN | afadin, adherens junction formation factor | 0.0323598 |
| ERBIN | erbb2 interacting protein | 0.0318612 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0315575 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0313842 |
| DEK | DEK proto-oncogene | 0.031348 |
| JAK1 | Janus kinase 1 | 0.0313313 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.031251 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.031135 |
| SFTPA2 | surfactant protein A2 | 0.0309248 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0307323 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0300188 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0299572 |
| MYOF | myoferlin | 0.0299564 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0297964 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0296637 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0291165 |
| FUS | FUS RNA binding protein | 0.0288602 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0284749 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0283879 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.305652 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.13927 |
| FTL | ferritin, light polypeptide | -0.0964089 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0795402 |
| EGR1 | early growth response 1 | -0.0757757 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0726817 |
| LOC112694756 | uncharaterized LOC112694756 | -0.069987 |
| TMSB10 | thymosin beta 10 | -0.0662531 |
| TAPBP | TAP binding protein (tapasin) | -0.0614921 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0517946 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0506197 |
| NDRG1 | N-myc downstream regulated 1 | -0.0497002 |
| HLA-B | major histocompatibility complex, class I, B | -0.0487191 |
| VCL | vinculin | -0.0458842 |
| TXNIP | thioredoxin interacting protein | -0.0455886 |
| CTSD | cathepsin D | -0.0408671 |
| VMP1 | vacuole membrane protein 1 | -0.0407658 |
| HLA-A | major histocompatibility complex, class I, A | -0.0394756 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0374007 |
| NABP1 | nucleic acid binding protein 1 | -0.0373672 |
| LDHA | lactate dehydrogenase A | -0.0372809 |
| LOX | lysyl oxidase | -0.0367787 |
| MORF4L2 | mortality factor 4 like 2 | -0.0362276 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0346148 |
| RPLP1 | ribosomal protein, large, P1 | -0.0345536 |
| GLIS3 | GLIS family zinc finger 3 | -0.0330511 |
| GPC6 | glypican 6 | -0.0328121 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0322258 |
| ATXN1 | ataxin 1 | -0.0286139 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.027526 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0273214 |
| DEPP1 | DEPP autophagy regulator 1 | -0.0268674 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0263462 |
| UBC | ubiquitin C | -0.0262995 |
| VIM | vimentin | -0.0262949 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0258589 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0254334 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0253362 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0253206 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0252349 |
| TSC22D2 | TSC22 domain family, member 2 | -0.024794 |
| RPS19 | ribosomal protein S19 | -0.0242004 |
| TNS3 | tensin 3 | -0.0241227 |
| C3 | complement component 3 | -0.0236375 |
| BICC1 | BicC family RNA binding protein 1 | -0.0235074 |
| BSG | basigin (Ok blood group) | -0.02335 |
| ARF4 | ADP-ribosylation factor 4 | -0.0231201 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0225911 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0225317 |
| KLF12 | Kruppel-like factor 12 | -0.0224853 |
| MT1X | metallothionein 1X | -0.0218112 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0215837 |
| HLA-E | major histocompatibility complex, class I, E | -0.0215745 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0215404 |
| CCNL1 | cyclin L1 | -0.0215365 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0206814 |
| SNX14 | sorting nexin 14 | -0.020383 |
| AGRN | agrin | -0.0202378 |
| WBP2 | WW domain binding protein 2 | -0.0201696 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.020136 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0200198 |
| HDAC9 | histone deacetylase 9 | -0.0199482 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0197674 |
| BPTF | bromodomain PHD finger transcription factor | -0.0195006 |
| INTS6 | integrator complex subunit 6 | -0.0193553 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0191656 |
| RPS4X | ribosomal protein S4, X-linked | -0.01902 |
| PRR16 | proline rich 16 | -0.0190056 |
| FOXO3 | forkhead box O3 | -0.0186583 |
| TUT7 | terminal uridylyl transferase 7 | -0.0180171 |
| RPL28 | ribosomal protein L28 | -0.0179762 |
| SEC24A | SEC24 family member A | -0.0179752 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0179336 |
| ASTN2 | astrotactin 2 | -0.0178865 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | -0.0178389 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.017807 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0176907 |
| PALLD | palladin, cytoskeletal associated protein | -0.0175096 |
| GRN | granulin | -0.0174173 |
| BRD2 | bromodomain containing 2 | -0.0172581 |
| PKM | pyruvate kinase, muscle | -0.0172238 |
| RPL30 | ribosomal protein L30 | -0.0171813 |
| DIAPH2 | diaphanous-related formin 2 | -0.0170801 |
| RPLP0 | ribosomal protein, large, P0 | -0.0170589 |
| RPL39 | ribosomal protein L39 | -0.0169908 |
| WASF2 | WAS protein family, member 2 | -0.0167552 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0165398 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0164003 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0162775 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0161815 |
| METTL15 | methyltransferase like 15 | -0.0160191 |
| RPL35A | ribosomal protein L35a | -0.0159653 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0159345 |
| SCARB1 | scavenger receptor class B, member 1 | -0.015433 |
| SNX3 | sorting nexin 3 | -0.0151689 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0151083 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0150353 |
| PHIP | pleckstrin homology domain interacting protein | -0.0149697 |
| ZNF207 | zinc finger protein 207 | -0.0148764 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0148087 |
