| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belumosudil_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.130279 |
| CDH13 | cadherin 13 | 0.105801 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.079676 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0720465 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0675722 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0574347 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0555978 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.054734 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0538406 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0515564 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.051315 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0509251 |
| ANLN | anillin, actin binding protein | 0.049386 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0493386 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0491343 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0490369 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0487514 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0479429 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0460085 |
| MAP1B | microtubule-associated protein 1B | 0.0460078 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0459751 |
| RPL5 | ribosomal protein L5 | 0.0453198 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0446844 |
| RHEB | Ras homolog enriched in brain | 0.0443844 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0438634 |
| CDC73 | cell division cycle 73 | 0.0438001 |
| DENND4C | DENN/MADD domain containing 4C | 0.0433161 |
| RAD51B | RAD51 paralog B | 0.0431775 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0428634 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0424064 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.042236 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0407168 |
| TMEM165 | transmembrane protein 165 | 0.0406825 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0401492 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0399763 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0398842 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0394164 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0392599 |
| AHNAK | AHNAK nucleoprotein | 0.0378795 |
| TFG | TRK-fused gene | 0.0375595 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0374264 |
| NOTCH2 | notch 2 | 0.0370963 |
| ATP13A3 | ATPase type 13A3 | 0.0370232 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0364897 |
| ANXA5 | annexin A5 | 0.0359199 |
| RNF145 | ring finger protein 145 | 0.0350394 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0348123 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0338022 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0337236 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.033722 |
| DNAAF9 | dynein axonemal assembly factor 9 | 0.0335449 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0328268 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0327862 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0326512 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0324032 |
| PDS5B | PDS5 cohesin associated factor B | 0.0323311 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0322646 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0322161 |
| ZNF292 | zinc finger protein 292 | 0.0321957 |
| TTK | TTK protein kinase | 0.0320811 |
| ITGA6 | integrin, alpha 6 | 0.0318738 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0317544 |
| PRELID2 | PRELI domain containing 2 | 0.0316455 |
| FLNA | filamin A, alpha | 0.0316394 |
| TJP1 | tight junction protein 1 | 0.0315642 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0315578 |
| BBX | bobby sox homolog (Drosophila) | 0.0313864 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0313428 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0312963 |
| PGK1 | phosphoglycerate kinase 1 | 0.0312829 |
| RPS19 | ribosomal protein S19 | 0.0310642 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | 0.0309667 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0309323 |
| SQSTM1 | sequestosome 1 | 0.0305518 |
| KATNAL1 | katanin p60 subunit A-like 1 | 0.0302194 |
| PTK2 | protein tyrosine kinase 2 | 0.0301755 |
| TXNRD1 | thioredoxin reductase 1 | 0.0301704 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0298703 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0298572 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0298035 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0297506 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0295627 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0295192 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0294704 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.02943 |
| RPS25 | ribosomal protein S25 | 0.0294111 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0293082 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0289905 |
| FRMD6 | FERM domain containing 6 | 0.0289904 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0289487 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0288143 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0287839 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0287169 |
| FMNL2 | formin-like 2 | 0.0284108 |
| ARRDC3 | arrestin domain containing 3 | 0.0284047 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0282968 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0282326 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0279576 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0279346 |
| DCP2 | decapping mRNA 2 | 0.0278296 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.288624 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.272722 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0891393 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0883275 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0804116 |
| TMSB10 | thymosin beta 10 | -0.0753705 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0683254 |
| LOC112694756 | uncharaterized LOC112694756 | -0.064886 |
| FTL | ferritin, light polypeptide | -0.0576705 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0570767 |
| ASPH | aspartate beta-hydroxylase | -0.0568275 |
| CALU | calumenin | -0.0566679 |
| SDC4 | syndecan 4 | -0.0548075 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0495001 |
| FN1 | fibronectin 1 | -0.0483765 |
| HLA-B | major histocompatibility complex, class I, B | -0.0469567 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0467116 |
| NDRG1 | N-myc downstream regulated 1 | -0.0458329 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0456662 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0453128 |
| GLG1 | golgi glycoprotein 1 | -0.0447199 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.044128 |
| EGFR | epidermal growth factor receptor | -0.0434919 |
| VIM | vimentin | -0.0423892 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0421424 |
| HM13 | histocompatibility (minor) 13 | -0.0420413 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0417265 |
| HIP1 | huntingtin interacting protein 1 | -0.0415505 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0407043 |
| SEPTIN7 | septin 7 | -0.0392508 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0390989 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0389688 |
| EGR1 | early growth response 1 | -0.0389345 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0383384 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0381443 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0371189 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0371073 |
| TGFB1 | transforming growth factor, beta 1 | -0.0367638 |
| CALD1 | caldesmon 1 | -0.0363265 |
| OGA | O-GlcNAcase | -0.0361482 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0360995 |
| LOX | lysyl oxidase | -0.0353823 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0348618 |
| SLC35E1 | solute carrier family 35, member E1 | -0.0347648 |
| CAVIN1 | caveolae associated protein 1 | -0.0344515 |
| BRD2 | bromodomain containing 2 | -0.034367 |
| UBC | ubiquitin C | -0.0341967 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.033989 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0333354 |
| PKM | pyruvate kinase, muscle | -0.0328163 |
| RRBP1 | ribosome binding protein 1 | -0.0327044 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.0323939 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0323704 |
| COMMD1 | copper metabolism (Murr1) domain containing 1 | -0.0319068 |
| HLA-A | major histocompatibility complex, class I, A | -0.0315971 |
| CLIC4 | chloride intracellular channel 4 | -0.0313505 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0312418 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.031093 |
| HBP1 | HMG-box transcription factor 1 | -0.0310124 |
| RPLP1 | ribosomal protein, large, P1 | -0.0305924 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0303581 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0303144 |
| KIF13A | kinesin family member 13A | -0.0300376 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0300008 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0299635 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0299421 |
| HIRA | histone cell cycle regulator | -0.0298231 |
| RAP1A | RAP1A, member of RAS oncogene family | -0.0296594 |
| C1D | C1D nuclear receptor corepressor | -0.0295399 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0294283 |
| ECE1 | endothelin converting enzyme 1 | -0.0293688 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0293349 |
| SCFD1 | sec1 family domain containing 1 | -0.0289079 |
| USP34 | ubiquitin specific peptidase 34 | -0.0287815 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0285743 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0285522 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0283993 |
| KLHDC10 | kelch domain containing 10 | -0.0282895 |
| CTSD | cathepsin D | -0.0282176 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0279747 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.027903 |
| CD99 | CD99 molecule | -0.0278807 |
| NEMF | nuclear export mediator factor | -0.0278499 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0278069 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0277744 |
| HLA-C | major histocompatibility complex, class I, C | -0.0277645 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0277638 |
| CCDC88A | coiled-coil domain containing 88A | -0.0276595 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0274347 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | -0.0274291 |
| MVP | major vault protein | -0.0273387 |
| CLCC1 | chloride channel CLIC-like 1 | -0.0271318 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -0.0270476 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0261309 |
| CDK6 | cyclin-dependent kinase 6 | -0.0260096 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0258666 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0256847 |
| TSPAN9 | tetraspanin 9 | -0.0254376 |
| CSNK1E | casein kinase 1, epsilon | -0.0253242 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0251378 |
