| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belumosudil_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.112277 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0845273 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0758613 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0734113 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0694446 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.066406 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0608398 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0602902 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.057569 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0547491 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0516797 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0500602 |
| GPC6 | glypican 6 | 0.0479855 |
| VIM | vimentin | 0.0478356 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0472039 |
| SBF2 | SET binding factor 2 | 0.0466559 |
| XPO1 | exportin 1 | 0.046284 |
| PARD3 | par-3 family cell polarity regulator | 0.0439695 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0434608 |
| ANXA5 | annexin A5 | 0.0433801 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.042965 |
| DNER | delta/notch-like EGF repeat containing | 0.0426981 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0413398 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.040865 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0406207 |
| NUP58 | nucleoporin 58 | 0.040448 |
| SET | SET nuclear proto-oncogene | 0.040285 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0393912 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0391747 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0387558 |
| SEC24A | SEC24 family member A | 0.0387032 |
| RPS8 | ribosomal protein S8 | 0.0378232 |
| CANX | calnexin | 0.0378135 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0377321 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0372324 |
| NPTN | neuroplastin | 0.036968 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0358607 |
| NBAS | neuroblastoma amplified sequence | 0.0357903 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0354983 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0354879 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.034755 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0342031 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0341366 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0340851 |
| AHNAK | AHNAK nucleoprotein | 0.0337211 |
| ZNF148 | zinc finger protein 148 | 0.0336681 |
| CUL3 | cullin 3 | 0.0333202 |
| RPL14 | ribosomal protein L14 | 0.0331993 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0328839 |
| PDE8A | phosphodiesterase 8A | 0.0327774 |
| HDLBP | high density lipoprotein binding protein | 0.0325949 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0325879 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0325658 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0323288 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0322415 |
| USP3 | ubiquitin specific peptidase 3 | 0.0319341 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0318493 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0318489 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0312929 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0312893 |
| NDRG1 | N-myc downstream regulated 1 | 0.0309826 |
| OLA1 | Obg-like ATPase 1 | 0.0305784 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.030496 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0301967 |
| HBP1 | HMG-box transcription factor 1 | 0.0297753 |
| GPR107 | G protein-coupled receptor 107 | 0.0296225 |
| MATR3 | matrin 3 | 0.0296184 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0294881 |
| RPL7 | ribosomal protein L7 | 0.0293522 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0290602 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0290515 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0290057 |
| TPM4 | tropomyosin 4 | 0.0287071 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0284565 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0281851 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0277333 |
| SEPTIN2 | septin 2 | 0.0277287 |
| RNF216 | ring finger protein 216 | 0.0276628 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0276342 |
| ARRDC3 | arrestin domain containing 3 | 0.027483 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0274527 |
| ATP13A3 | ATPase type 13A3 | 0.0274235 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0271538 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 | 0.0270795 |
| RAB5A | RAB5A, member RAS oncogene family | 0.0270068 |
| PRELID2 | PRELI domain containing 2 | 0.0269481 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0268868 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0266607 |
| COPA | coatomer protein complex, subunit alpha | 0.0265378 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0264451 |
| SEC24D | SEC24 family member D | 0.0264248 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | 0.0261856 |
| MAP1B | microtubule-associated protein 1B | 0.0261852 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0259881 |
| RNF145 | ring finger protein 145 | 0.0259736 |
| COLEC11 | collectin sub-family member 11 | 0.0259116 |
| ITSN2 | intersectin 2 | 0.0257842 |
| ATL2 | atlastin GTPase 2 | 0.0257549 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.025633 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0255932 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.180875 |
| DST | dystonin | -0.0773496 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0726303 |
| SMYD3 | SET and MYND domain containing 3 | -0.070302 |
| LOC112694756 | uncharaterized LOC112694756 | -0.069241 |
| ERBIN | erbb2 interacting protein | -0.0679081 |
| MT2A | metallothionein 2A | -0.0663846 |
| ATM | ATM serine/threonine kinase | -0.0625308 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0622613 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.061441 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0602885 |
| TMSB10 | thymosin beta 10 | -0.0590766 |
| YBX3 | Y box binding protein 3 | -0.058645 |
| LDHA | lactate dehydrogenase A | -0.0573814 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0563628 |
| CENPF | centromere protein F, 350/400kDa | -0.0555062 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0550432 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0541902 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.053949 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0520625 |
| RPLP1 | ribosomal protein, large, P1 | -0.0515702 |
| OSMR | oncostatin M receptor | -0.0503305 |
| FBXO11 | F-box protein 11 | -0.0503182 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0501136 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0497938 |
| IGF2 | insulin-like growth factor 2 | -0.0496591 |
| RBM39 | RNA binding motif protein 39 | -0.0491556 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0466057 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0446678 |
| NLK | nemo-like kinase | -0.044468 |
| SSH2 | slingshot protein phosphatase 2 | -0.0442728 |
| CKAP2 | cytoskeleton associated protein 2 | -0.043897 |
| CCNH | cyclin H | -0.0432595 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | -0.0422854 |
| PHF20 | PHD finger protein 20 | -0.0416522 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0414357 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0413865 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0399375 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.039879 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.039396 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0390885 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.03886 |
| CPNE1 | copine I | -0.0383841 |
| RPL36 | ribosomal protein L36 | -0.0380853 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0367381 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0365888 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0365458 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.036322 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0359691 |
| OSBPL6 | oxysterol binding protein-like 6 | -0.035288 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0350833 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0348673 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0348561 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0348527 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0347506 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0347375 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0346852 |
| HDAC9 | histone deacetylase 9 | -0.0344605 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0340862 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0339539 |
| TPX2 | TPX2, microtubule-associated | -0.0339517 |
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | -0.0339307 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.033414 |
| RBMX | RNA binding motif protein, X-linked | -0.0331009 |
| RPL26 | ribosomal protein L26 | -0.0330246 |
| USP34 | ubiquitin specific peptidase 34 | -0.0323172 |
| TXNIP | thioredoxin interacting protein | -0.0321892 |
| NBEAL1 | neurobeachin-like 1 | -0.0321048 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0316788 |
| YAP1 | Yes-associated protein 1 | -0.0315191 |
| EFL1 | elongation factor like GTPase 1 | -0.0314186 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0313154 |
| RDX | radixin | -0.0311789 |
| LMO7 | LIM domain 7 | -0.0308285 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0306982 |
| GOLGA4 | golgin A4 | -0.0306172 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0305092 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0304906 |
| RPS29 | ribosomal protein S29 | -0.0302478 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0300335 |
| DGKH | diacylglycerol kinase, eta | -0.0298387 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0296945 |
| ANLN | anillin, actin binding protein | -0.0295568 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0291526 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0289833 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0289348 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0286393 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0285286 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.028467 |
| NF1 | neurofibromin 1 | -0.0284425 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0284172 |
| ANGPTL4 | angiopoietin-like 4 | -0.0283981 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0283414 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0282082 |
| VMP1 | vacuole membrane protein 1 | -0.0280033 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0278722 |
| CEP350 | centrosomal protein 350kDa | -0.0278036 |
| PRR11 | proline rich 11 | -0.0278009 |
| CNKSR3 | CNKSR family member 3 | -0.0273964 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0269883 |
