| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belzutifan perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belzutifan_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | 0.141574 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.124943 |
| PODXL | podocalyxin-like | 0.0954316 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0945801 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.092577 |
| RPL12 | ribosomal protein L12 | 0.0839848 |
| MYOF | myoferlin | 0.082223 |
| ENO1 | enolase 1, (alpha) | 0.0817605 |
| HLA-B | major histocompatibility complex, class I, B | 0.0759448 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.073513 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0704786 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0700836 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0696434 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.06771 |
| CD44 | CD44 molecule (Indian blood group) | 0.0669423 |
| RPS12 | ribosomal protein S12 | 0.0667528 |
| RPS19 | ribosomal protein S19 | 0.0665152 |
| OSMR | oncostatin M receptor | 0.065056 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0637271 |
| RPL26 | ribosomal protein L26 | 0.0621387 |
| DST | dystonin | 0.0602121 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0596261 |
| RASAL2 | RAS protein activator like 2 | 0.0514995 |
| IGF2 | insulin-like growth factor 2 | 0.0514409 |
| RPS6 | ribosomal protein S6 | 0.0511697 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0506395 |
| RPL37A | ribosomal protein L37a | 0.0503633 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0499098 |
| CLU | clusterin | 0.0491947 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0489213 |
| ANXA2 | annexin A2 | 0.0485353 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0482222 |
| AOPEP | aminopeptidase O (putative) | 0.047923 |
| LDHA | lactate dehydrogenase A | 0.0474009 |
| RPLP2 | ribosomal protein, large, P2 | 0.0455384 |
| RAI14 | retinoic acid induced 14 | 0.0444135 |
| RACK1 | receptor for activated C kinase 1 | 0.043488 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0423226 |
| RPL13A | ribosomal protein L13a | 0.0418563 |
| PKM | pyruvate kinase, muscle | 0.0412546 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0410176 |
| CSTB | cystatin B (stefin B) | 0.0408458 |
| RPS2 | ribosomal protein S2 | 0.0408169 |
| ASPH | aspartate beta-hydroxylase | 0.0401603 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0400974 |
| ANGPTL4 | angiopoietin-like 4 | 0.0399985 |
| AHNAK | AHNAK nucleoprotein | 0.0395813 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0394378 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0391738 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.038653 |
| RPL36 | ribosomal protein L36 | 0.0377848 |
| RPS3 | ribosomal protein S3 | 0.0377595 |
| RPL30 | ribosomal protein L30 | 0.0375894 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0368564 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0366475 |
| PRELID2 | PRELI domain containing 2 | 0.036239 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0359229 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.035767 |
| RPS27 | ribosomal protein S27 | 0.035607 |
| RPS17 | ribosomal protein S17 | 0.0350898 |
| DOCK4 | dedicator of cytokinesis 4 | 0.034999 |
| PMP22 | peripheral myelin protein 22 | 0.0348815 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0342021 |
| MT2A | metallothionein 2A | 0.0341046 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0338525 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0336471 |
| IFI44L | interferon-induced protein 44-like | 0.0332116 |
| ADAR | adenosine deaminase, RNA-specific | 0.0328959 |
| RPL35 | ribosomal protein L35 | 0.0326334 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0325918 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0325877 |
| IFI44 | interferon-induced protein 44 | 0.0322733 |
| RPL4 | ribosomal protein L4 | 0.0319372 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0314901 |
| RPLP0 | ribosomal protein, large, P0 | 0.0312809 |
| CAVIN1 | caveolae associated protein 1 | 0.0310544 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0308207 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0307161 |
| RPS15 | ribosomal protein S15 | 0.0306478 |
| HLA-A | major histocompatibility complex, class I, A | 0.0306249 |
| S100A10 | S100 calcium binding protein A10 | 0.0303094 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0299094 |
| NRG1 | neuregulin 1 | 0.0297606 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.029668 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0293585 |
| SMAD3 | SMAD family member 3 | 0.029307 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0291394 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0291246 |
| SULF2 | sulfatase 2 | 0.0287127 |
| RPS8 | ribosomal protein S8 | 0.0285813 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0284244 |
| RPL32 | ribosomal protein L32 | 0.0283903 |
| RPL11 | ribosomal protein L11 | 0.0279887 |
| PGK1 | phosphoglycerate kinase 1 | 0.0278894 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0269836 |
| MTPN | myotrophin | 0.0269298 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0269186 |
| ACER3 | alkaline ceramidase 3 | 0.0268646 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.026642 |
| EFCAB14 | EF-hand calcium binding domain 14 | 0.0265956 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | -0.0851392 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0826525 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0702519 |
| NDRG1 | N-myc downstream regulated 1 | -0.065953 |
| MTSS1 | metastasis suppressor 1 | -0.0593758 |
| PTMA | prothymosin, alpha | -0.0565437 |
| INTS6 | integrator complex subunit 6 | -0.0546694 |
| LMO7 | LIM domain 7 | -0.05038 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0482919 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0480978 |
| FOXO1 | forkhead box O1 | -0.0471469 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0470048 |
| MEF2A | myocyte enhancer factor 2A | -0.0447651 |
| EMP1 | epithelial membrane protein 1 | -0.0437014 |
| POTEF | POTE ankyrin domain family, member F | -0.0404882 |
| SPAG9 | sperm associated antigen 9 | -0.0389405 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0378286 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0367435 |
| EZR | ezrin | -0.0355442 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0337057 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0336523 |
| PALLD | palladin, cytoskeletal associated protein | -0.0326722 |
| SULF1 | sulfatase 1 | -0.0323793 |
| OGA | O-GlcNAcase | -0.0318413 |
| ARF4 | ADP-ribosylation factor 4 | -0.0313915 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0307482 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0305361 |
| KRT17 | keratin 17, type I | -0.0292271 |
| EFHD2 | EF-hand domain family, member D2 | -0.028324 |
| SRPK2 | SRSF protein kinase 2 | -0.0280838 |
| HMGA1 | high mobility group AT-hook 1 | -0.028082 |
| MKI67 | marker of proliferation Ki-67 | -0.0278622 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0277778 |
| TPM4 | tropomyosin 4 | -0.0274766 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0271747 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0271599 |
| HM13 | histocompatibility (minor) 13 | -0.0267299 |
| COG6 | component of oligomeric golgi complex 6 | -0.0263656 |
| PDS5B | PDS5 cohesin associated factor B | -0.0254879 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.025393 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0252933 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0252144 |
| NECTIN1 | nectin cell adhesion molecule 1 | -0.0249485 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0248907 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0246999 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0246375 |
| FOXO3 | forkhead box O3 | -0.024559 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0239395 |
| STC1 | stanniocalcin 1 | -0.0238052 |
| EGR1 | early growth response 1 | -0.0235243 |
| DIAPH3 | diaphanous-related formin 3 | -0.0233347 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0231852 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0229603 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0222996 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0219371 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0217607 |
| UTRN | utrophin | -0.0215986 |
| TPX2 | TPX2, microtubule-associated | -0.0211065 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.0204004 |
| S100A9 | S100 calcium binding protein A9 | -0.0203565 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0201367 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.020035 |
| ANLN | anillin, actin binding protein | -0.019949 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0197537 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0197137 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0195858 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0194867 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0193973 |
| MT1E | metallothionein 1E | -0.0193868 |
| KRT14 | keratin 14, type I | -0.019378 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.019329 |
| MECOM | MDS1 and EVI1 complex locus | -0.0191563 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0190535 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.0187899 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.018661 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0185939 |
| KIAA1671 | KIAA1671 | -0.0185734 |
| CLMB | calcimembrin | -0.0183509 |
| RASA3 | RAS p21 protein activator 3 | -0.0183393 |
| RHEB | Ras homolog enriched in brain | -0.0183106 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0182866 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.018069 |
| ATOSA | atos homolog A | -0.0177849 |
| TNS3 | tensin 3 | -0.0177409 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0176936 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.0176287 |
| MYO9B | myosin IXB | -0.0174901 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.01747 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.0174664 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0174526 |
| KIF16B | kinesin family member 16B | -0.0173976 |
| KLHL24 | kelch-like family member 24 | -0.0173518 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0172683 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0171305 |
| FBXO11 | F-box protein 11 | -0.017039 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0170276 |
| HLA-E | major histocompatibility complex, class I, E | -0.0169377 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0168626 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0168215 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.0167139 |
