| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belzutifan perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belzutifan_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.274495 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.195025 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.110278 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0809199 |
| FTL | ferritin, light polypeptide | 0.0603291 |
| H1-0 | H1.0 linker histone | 0.0567073 |
| PIGR | polymeric immunoglobulin receptor | 0.0503089 |
| EREG | epiregulin | 0.0480391 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0480088 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.045962 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0458631 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0427525 |
| DSPP | dentin sialophosphoprotein | 0.0410486 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.038722 |
| NEBL | nebulette | 0.0387174 |
| FOXP1 | forkhead box P1 | 0.0384524 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0371534 |
| ACTG1 | actin gamma 1 | 0.0371007 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0370828 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0362618 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0355585 |
| CD44 | CD44 molecule (Indian blood group) | 0.0332902 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0320583 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0315734 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0310931 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0307625 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0305619 |
| LMO7 | LIM domain 7 | 0.0303501 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0302736 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0300589 |
| RPL12 | ribosomal protein L12 | 0.0298039 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0294154 |
| PTMA | prothymosin, alpha | 0.0291518 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0287252 |
| SMYD3 | SET and MYND domain containing 3 | 0.0284403 |
| RPL4 | ribosomal protein L4 | 0.0272735 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0271299 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0267519 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0266524 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0264346 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0263605 |
| RPS12 | ribosomal protein S12 | 0.0261498 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0261095 |
| DSG2 | desmoglein 2 | 0.0259449 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0257933 |
| FAM13A | family with sequence similarity 13, member A | 0.0256051 |
| MUC13 | mucin 13, cell surface associated | 0.0252762 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0251404 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0250373 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0238373 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0233357 |
| EXPH5 | exophilin 5 | 0.0233181 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0229062 |
| EHF | ets homologous factor | 0.0221745 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0217676 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0215583 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0214146 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0207929 |
| PDZD8 | PDZ domain containing 8 | 0.0204827 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0203404 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0199757 |
| TMC5 | transmembrane channel-like 5 | 0.0195773 |
| H1-4 | H1.4 linker histone, cluster member | 0.0195731 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.019545 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0193576 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0191534 |
| ENO1 | enolase 1, (alpha) | 0.0189462 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0189247 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0189141 |
| SPATA13 | spermatogenesis associated 13 | 0.0186448 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0186447 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0185988 |
| RPL7A | ribosomal protein L7a | 0.0185424 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0185362 |
| MUC17 | mucin 17, cell surface associated | 0.0185332 |
| MACROD2 | MACRO domain containing 2 | 0.018237 |
| ATXN1 | ataxin 1 | 0.017985 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0179248 |
| RPL6 | ribosomal protein L6 | 0.0178774 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0178576 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0178432 |
| RPS27A | ribosomal protein S27a | 0.0177477 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0173012 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0172458 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0170621 |
| PRDX1 | peroxiredoxin 1 | 0.0169847 |
| PCBP1 | poly(rC) binding protein 1 | 0.0167386 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | 0.0165044 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0162672 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0160457 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0159484 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0156307 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.015372 |
| RPS2 | ribosomal protein S2 | 0.0153707 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0153472 |
| KLF6 | Kruppel-like factor 6 | 0.0153282 |
| FYTTD1 | forty-two-three domain containing 1 | 0.0152889 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0152372 |
| GOLIM4 | golgi integral membrane protein 4 | 0.015205 |
| SET | SET nuclear proto-oncogene | 0.0150718 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.141704 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.123773 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.11993 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.116249 |
| TMSB10 | thymosin beta 10 | -0.113026 |
| ITGA6 | integrin, alpha 6 | -0.103864 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0989049 |
| VCL | vinculin | -0.0954706 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0888532 |
| NDRG1 | N-myc downstream regulated 1 | -0.0840667 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0825175 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.080939 |
| VEGFA | vascular endothelial growth factor A | -0.0790038 |
| FAT1 | FAT atypical cadherin 1 | -0.0785318 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0757989 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0746245 |
| LAMA4 | laminin, alpha 4 | -0.0739383 |
| PKM | pyruvate kinase, muscle | -0.0732193 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.067308 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0664328 |
| FLNB | filamin B, beta | -0.0659753 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0585642 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.054868 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0536301 |
| ACTN4 | actinin, alpha 4 | -0.0523331 |
| ANXA2 | annexin A2 | -0.0519819 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0488752 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0486615 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0485366 |
| VMP1 | vacuole membrane protein 1 | -0.0484809 |
| RCOR1 | REST corepressor 1 | -0.0471931 |
| EGR1 | early growth response 1 | -0.0464558 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0464184 |
| POTEF | POTE ankyrin domain family, member F | -0.04579 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0456926 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.044732 |
| CALB1 | calbindin 1, 28kDa | -0.0444637 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0433277 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0428122 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0422787 |
| SPAG9 | sperm associated antigen 9 | -0.0420336 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0419925 |
| FHL2 | four and a half LIM domains 2 | -0.0419193 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0413885 |
| FBXO11 | F-box protein 11 | -0.0413005 |
| HMGA1 | high mobility group AT-hook 1 | -0.0403206 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0394896 |
| YBX1 | Y box binding protein 1 | -0.0392212 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0389562 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0387029 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0386966 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0385233 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0380495 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0378483 |
| TFG | TRK-fused gene | -0.0377904 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0375601 |
| RNF145 | ring finger protein 145 | -0.0371652 |
| CALR | calreticulin | -0.0356322 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0353126 |
| RBM39 | RNA binding motif protein 39 | -0.0342753 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0342726 |
| FNBP1L | formin binding protein 1-like | -0.0342579 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0342029 |
| MYO1E | myosin IE | -0.0341956 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0339736 |
| ARF4 | ADP-ribosylation factor 4 | -0.0337298 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0333254 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0331293 |
| PARD3 | par-3 family cell polarity regulator | -0.0330988 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0330828 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0326255 |
| EFNB2 | ephrin-B2 | -0.0324112 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.032173 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0319001 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0315632 |
| MSI2 | musashi RNA-binding protein 2 | -0.0314688 |
| FRMD5 | FERM domain containing 5 | -0.03118 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0307513 |
| FOXO1 | forkhead box O1 | -0.0304011 |
| KRT8 | keratin 8, type II | -0.0302687 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.030246 |
| LDHA | lactate dehydrogenase A | -0.0300868 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0300487 |
| MXD1 | MAX dimerization protein 1 | -0.0300275 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0299932 |
| FOXO3 | forkhead box O3 | -0.0297264 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0295853 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0293935 |
| S100A14 | S100 calcium binding protein A14 | -0.0293652 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0291895 |
| SFPQ | splicing factor proline/glutamine-rich | -0.029092 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0289909 |
| ONECUT3 | one cut homeobox 3 | -0.0289328 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0287331 |
| RIN2 | Ras and Rab interactor 2 | -0.0286868 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0285417 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0284218 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0284038 |
| MORF4L2 | mortality factor 4 like 2 | -0.0282381 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0279155 |
