| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belzutifan perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belzutifan_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HDAC9 | histone deacetylase 9 | 0.155049 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.102076 |
| MT2A | metallothionein 2A | 0.0960703 |
| CD44 | CD44 molecule (Indian blood group) | 0.0946993 |
| RPS12 | ribosomal protein S12 | 0.0751868 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0713725 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0644618 |
| VIM | vimentin | 0.0626131 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0591564 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0579202 |
| RPS3 | ribosomal protein S3 | 0.0565323 |
| RPL37A | ribosomal protein L37a | 0.0558933 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0541732 |
| STC1 | stanniocalcin 1 | 0.0484417 |
| HMGA2 | high mobility group AT-hook 2 | 0.0483073 |
| NAV2 | neuron navigator 2 | 0.0468416 |
| ENO1 | enolase 1, (alpha) | 0.0464114 |
| ASPH | aspartate beta-hydroxylase | 0.0462136 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0457948 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0454732 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0453598 |
| RND3 | Rho family GTPase 3 | 0.0435254 |
| KYNU | kynureninase | 0.0434085 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0431823 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0431599 |
| INTS6 | integrator complex subunit 6 | 0.0426865 |
| GPC6 | glypican 6 | 0.0424149 |
| SQSTM1 | sequestosome 1 | 0.0420145 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.041862 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0409216 |
| FNIP1 | folliculin interacting protein 1 | 0.0380339 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0362577 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0360625 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0356784 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0348175 |
| HLA-A | major histocompatibility complex, class I, A | 0.0343669 |
| GOLGB1 | golgin B1 | 0.0338523 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0331198 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0330618 |
| HLA-B | major histocompatibility complex, class I, B | 0.032823 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0326791 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.032566 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0313955 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0307215 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0300718 |
| CDH13 | cadherin 13 | 0.0300217 |
| RPL9 | ribosomal protein L9 | 0.0294176 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0293466 |
| RPS8 | ribosomal protein S8 | 0.0290228 |
| RPS17 | ribosomal protein S17 | 0.0289408 |
| RPL4 | ribosomal protein L4 | 0.0284999 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0284856 |
| BICC1 | BicC family RNA binding protein 1 | 0.0280754 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0278798 |
| TMEM132D | transmembrane protein 132D | 0.0277751 |
| RACK1 | receptor for activated C kinase 1 | 0.0275854 |
| ATXN1 | ataxin 1 | 0.0270779 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0268304 |
| FTL | ferritin, light polypeptide | 0.02677 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0265365 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0263605 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0262769 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.026197 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0259577 |
| INHBA | inhibin, beta A | 0.0257813 |
| DUSP10 | dual specificity phosphatase 10 | 0.0256185 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0250541 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.024951 |
| TGM2 | transglutaminase 2 | 0.0244851 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.023913 |
| SVIL | supervillin | 0.023094 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0230575 |
| SP100 | SP100 nuclear antigen | 0.0230502 |
| RPL19 | ribosomal protein L19 | 0.0230001 |
| RPS23 | ribosomal protein S23 | 0.0225662 |
| EFNA5 | ephrin-A5 | 0.022475 |
| RPL26 | ribosomal protein L26 | 0.0222683 |
| PMP22 | peripheral myelin protein 22 | 0.0222063 |
| RPL12 | ribosomal protein L12 | 0.0221677 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0220767 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0220659 |
| VCL | vinculin | 0.021624 |
| JMJD1C | jumonji domain containing 1C | 0.0215081 |
| TRIM55 | tripartite motif containing 55 | 0.0214491 |
| WWOX | WW domain containing oxidoreductase | 0.0211502 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0211214 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0209408 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0208617 |
| HOMER1 | homer scaffolding protein 1 | 0.0203681 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0201404 |
| RPL5 | ribosomal protein L5 | 0.0199435 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0198833 |
| FLOT1 | flotillin 1 | 0.0198337 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 0.0194786 |
| RUNX1 | runt-related transcription factor 1 | 0.0194492 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.019437 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0194337 |
| FOSL1 | FOS-like antigen 1 | 0.0193954 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0193026 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.019154 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.271717 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.186711 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.119908 |
| CADM1 | cell adhesion molecule 1 | -0.101595 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.086124 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0826191 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0755053 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0716514 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0690118 |
| VEGFA | vascular endothelial growth factor A | -0.061183 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0594244 |
| ZNF292 | zinc finger protein 292 | -0.0587613 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0585853 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0562053 |
| FRMD4A | FERM domain containing 4A | -0.0552705 |
| ATP13A3 | ATPase type 13A3 | -0.0535687 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0516036 |
| SPAG9 | sperm associated antigen 9 | -0.0511939 |
| OGA | O-GlcNAcase | -0.0497617 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0465323 |
| HELZ | helicase with zinc finger | -0.0454976 |
| RBM39 | RNA binding motif protein 39 | -0.0454626 |
| PDE10A | phosphodiesterase 10A | -0.0436262 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0434758 |
| RTN4 | reticulon 4 | -0.0434194 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.041452 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0403917 |
| FOXO3 | forkhead box O3 | -0.0403736 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0398141 |
| QKI | QKI, KH domain containing, RNA binding | -0.0395253 |
| ADM | adrenomedullin | -0.0382979 |
| CTSD | cathepsin D | -0.0378894 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.037645 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0375315 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0367673 |
| WDR45B | WD repeat domain 45B | -0.0350896 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0350667 |
| MATR3 | matrin 3 | -0.0349905 |
| PHF21A | PHD finger protein 21A | -0.0348822 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0345114 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0342304 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.033947 |
| TMEM123 | transmembrane protein 123 | -0.0338815 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0334848 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0333176 |
| YBX1 | Y box binding protein 1 | -0.0330583 |
| TAPBP | TAP binding protein (tapasin) | -0.0324 |
| ANLN | anillin, actin binding protein | -0.0320791 |
| RLF | rearranged L-myc fusion | -0.0316584 |
| COL1A2 | collagen, type I, alpha 2 | -0.0313559 |
| KIF13A | kinesin family member 13A | -0.031161 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0311605 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0311184 |
| GOLGA4 | golgin A4 | -0.0309186 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0308073 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0305784 |
| TFG | TRK-fused gene | -0.0304708 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0304652 |
| PTMA | prothymosin, alpha | -0.0302053 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0300475 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.029936 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0298876 |
| ARF4 | ADP-ribosylation factor 4 | -0.0294859 |
| GNAS | GNAS complex locus | -0.0293452 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0289529 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.028784 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.028217 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0280737 |
| CANX | calnexin | -0.0280474 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0280133 |
| ZNF207 | zinc finger protein 207 | -0.0279723 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0275401 |
| TPM4 | tropomyosin 4 | -0.0271991 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0271088 |
| USP37 | ubiquitin specific peptidase 37 | -0.0267785 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0265251 |
| TXNRD1 | thioredoxin reductase 1 | -0.0264568 |
| TUBB | tubulin, beta class I | -0.0264433 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0262056 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0260171 |
| DST | dystonin | -0.0258164 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0257442 |
| WTAP | Wilms tumor 1 associated protein | -0.0254302 |
| MAP4 | microtubule-associated protein 4 | -0.0253932 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0252934 |
| DENND5A | DENN/MADD domain containing 5A | -0.0251793 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0251037 |
| UBC | ubiquitin C | -0.0250005 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0248397 |
| PCBP2 | poly(rC) binding protein 2 | -0.024834 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0248247 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.024713 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0246061 |
| RNF145 | ring finger protein 145 | -0.0244023 |
| SBF2 | SET binding factor 2 | -0.0243475 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0241816 |
| RAB1A | RAB1A, member RAS oncogene family | -0.02416 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0240142 |
| TMSB4X | thymosin beta 4, X-linked | -0.0237043 |
| SEPTIN7 | septin 7 | -0.0236762 |
