| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belzutifan perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belzutifan_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.270308 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.227773 |
| KYNU | kynureninase | 0.0686852 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0632485 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0598964 |
| MT2A | metallothionein 2A | 0.0569209 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0529378 |
| FTL | ferritin, light polypeptide | 0.0508662 |
| FAM13A | family with sequence similarity 13, member A | 0.0507813 |
| RACK1 | receptor for activated C kinase 1 | 0.0465441 |
| HLA-A | major histocompatibility complex, class I, A | 0.0461898 |
| ENO1 | enolase 1, (alpha) | 0.0461085 |
| FNIP1 | folliculin interacting protein 1 | 0.0441268 |
| B2M | beta-2-microglobulin | 0.0423052 |
| RPS8 | ribosomal protein S8 | 0.0420264 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0367884 |
| RPL37A | ribosomal protein L37a | 0.0366636 |
| RPS12 | ribosomal protein S12 | 0.036565 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0341285 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0335793 |
| RPS3 | ribosomal protein S3 | 0.0310749 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0304362 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0303354 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0301438 |
| RPS6 | ribosomal protein S6 | 0.0300457 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0300027 |
| RPL11 | ribosomal protein L11 | 0.0296894 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0296489 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0293809 |
| SEC24D | SEC24 family member D | 0.0289899 |
| RPL9 | ribosomal protein L9 | 0.0287749 |
| RPL12 | ribosomal protein L12 | 0.0280773 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0280208 |
| STC1 | stanniocalcin 1 | 0.027868 |
| HDAC9 | histone deacetylase 9 | 0.0276402 |
| RPL26 | ribosomal protein L26 | 0.0272753 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0256276 |
| ZNF395 | zinc finger protein 395 | 0.0256216 |
| RPL28 | ribosomal protein L28 | 0.0252482 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0250544 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0249263 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.024838 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0247432 |
| RPL18 | ribosomal protein L18 | 0.0243495 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0241297 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0241258 |
| RPL5 | ribosomal protein L5 | 0.0241178 |
| INTS6 | integrator complex subunit 6 | 0.0240419 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0237568 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0227616 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0221757 |
| TMF1 | TATA element modulatory factor 1 | 0.0220402 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0218951 |
| RPS23 | ribosomal protein S23 | 0.0218631 |
| RPS27A | ribosomal protein S27a | 0.0213956 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0209768 |
| CALD1 | caldesmon 1 | 0.0209412 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0208005 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0206751 |
| EFCAB14 | EF-hand calcium binding domain 14 | 0.020452 |
| MCL1 | myeloid cell leukemia 1 | 0.0204407 |
| CANX | calnexin | 0.0202231 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0199038 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0195804 |
| RPL31 | ribosomal protein L31 | 0.0194339 |
| MTPN | myotrophin | 0.0192714 |
| RPS2 | ribosomal protein S2 | 0.0191546 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.019152 |
| PTN | pleiotrophin | 0.0190707 |
| MPZ | myelin protein zero | 0.0189762 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0188526 |
| RPS14 | ribosomal protein S14 | 0.0187954 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.018755 |
| EREG | epiregulin | 0.0187235 |
| NPTN | neuroplastin | 0.0187208 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0185991 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0185425 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0183937 |
| BPTF | bromodomain PHD finger transcription factor | 0.0183208 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0180905 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0180741 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0179739 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0179525 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0179151 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0178953 |
| GSE1 | Gse1 coiled-coil protein | 0.0178395 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0176685 |
| JPH2 | junctophilin 2 | 0.017439 |
| C1D | C1D nuclear receptor corepressor | 0.0174312 |
| VIM | vimentin | 0.0173825 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0173798 |
| SETD5 | SET domain containing 5 | 0.0173647 |
| WASF2 | WAS protein family, member 2 | 0.0173057 |
| BRD4 | bromodomain containing 4 | 0.0172715 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0172442 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0172229 |
| RAB10 | RAB10, member RAS oncogene family | 0.0172162 |
| RPL15 | ribosomal protein L15 | 0.0171614 |
| FTO | fat mass and obesity associated | 0.0171223 |
| PCBP2 | poly(rC) binding protein 2 | 0.0170385 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.203662 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0942936 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.084962 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0824766 |
| FN1 | fibronectin 1 | -0.0795689 |
| TMSB10 | thymosin beta 10 | -0.0755182 |
| LOX | lysyl oxidase | -0.0749852 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0744152 |
| COL1A2 | collagen, type I, alpha 2 | -0.0706732 |
| CALU | calumenin | -0.0687288 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0671552 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0651665 |
| HMGA2 | high mobility group AT-hook 2 | -0.0494935 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.04797 |
| MT1X | metallothionein 1X | -0.0443266 |
| LOXL2 | lysyl oxidase-like 2 | -0.0415188 |
| GLIS3 | GLIS family zinc finger 3 | -0.0404363 |
| TMSB4X | thymosin beta 4, X-linked | -0.0403084 |
| COL1A1 | collagen, type I, alpha 1 | -0.0401612 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.039485 |
| HLA-B | major histocompatibility complex, class I, B | -0.0385145 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0355983 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0355739 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0349656 |
| TUBB | tubulin, beta class I | -0.0347825 |
| PRSS23 | protease, serine, 23 | -0.0340276 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.03368 |
| POTEF | POTE ankyrin domain family, member F | -0.0335171 |
| CADM1 | cell adhesion molecule 1 | -0.0334552 |
| CAVIN1 | caveolae associated protein 1 | -0.0330354 |
| TPM4 | tropomyosin 4 | -0.0328526 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0315057 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0313127 |
| COL3A1 | collagen, type III, alpha 1 | -0.0308596 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0304753 |
| ANLN | anillin, actin binding protein | -0.0300766 |
| RRBP1 | ribosome binding protein 1 | -0.0298265 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0296391 |
| COL5A1 | collagen, type V, alpha 1 | -0.0294536 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0291976 |
| PTMA | prothymosin, alpha | -0.0288105 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0284168 |
| FAM20C | family with sequence similarity 20, member C | -0.0283069 |
| VCL | vinculin | -0.0282137 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0280345 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0277772 |
| SLC25A51 | solute carrier family 25, member 51 | -0.0277122 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0277084 |
| RASA3 | RAS p21 protein activator 3 | -0.0277031 |
| GLG1 | golgi glycoprotein 1 | -0.0275535 |
| SRPK2 | SRSF protein kinase 2 | -0.0272728 |
| CDH13 | cadherin 13 | -0.0272425 |
| SDC4 | syndecan 4 | -0.0265955 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.026539 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0260907 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0257376 |
| RTN4 | reticulon 4 | -0.0255803 |
| AHNAK | AHNAK nucleoprotein | -0.0255798 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0255419 |
| DIAPH3 | diaphanous-related formin 3 | -0.024548 |
| PARD3 | par-3 family cell polarity regulator | -0.0245125 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0244677 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0237405 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0235872 |
| TAGLN2 | transgelin 2 | -0.0233991 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0226435 |
| PYGL | phosphorylase, glycogen, liver | -0.0224958 |
| EFNA5 | ephrin-A5 | -0.0218806 |
| TNNC1 | troponin C type 1 (slow) | -0.0217865 |
| SEPTIN11 | septin 11 | -0.0216036 |
| TPM1 | tropomyosin 1 (alpha) | -0.0215213 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0211344 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0211261 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0210569 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | -0.0209546 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0208093 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | -0.0206577 |
| COL5A2 | collagen, type V, alpha 2 | -0.0203016 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | -0.0199285 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0198503 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.019615 |
| ACTG1 | actin gamma 1 | -0.0194668 |
| RPL35A | ribosomal protein L35a | -0.0194655 |
| NABP1 | nucleic acid binding protein 1 | -0.0194502 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0194116 |
| ZNF292 | zinc finger protein 292 | -0.0190706 |
| BBX | bobby sox homolog (Drosophila) | -0.0188831 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.0187729 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0187519 |
| CCDC88A | coiled-coil domain containing 88A | -0.0187236 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0186981 |
| ERBIN | erbb2 interacting protein | -0.0186418 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0183003 |
| COL4A2 | collagen, type IV, alpha 2 | -0.018259 |
| MORC3 | MORC family CW-type zinc finger 3 | -0.0182551 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0182247 |
| ETV6 | ets variant 6 | -0.0181285 |
| SUN1 | Sad1 and UNC84 domain containing 1 | -0.0181223 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0180688 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0178642 |
