| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bendamustine perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bendamustine_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0484916 |
| POTEF | POTE ankyrin domain family, member F | 0.0436444 |
| CDH13 | cadherin 13 | 0.0393563 |
| FN1 | fibronectin 1 | 0.0356298 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.029681 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.0277532 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0236577 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0235022 |
| SUCNR1 | succinate receptor 1 | 0.0206847 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.015132 |
| EGFR | epidermal growth factor receptor | 0.0149819 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0148932 |
| PLXNA2 | plexin A2 | 0.0139851 |
| LRRC17 | leucine rich repeat containing 17 | 0.0136441 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0135119 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.01341 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0121115 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0110827 |
| FLT1 | fms-related tyrosine kinase 1 | 0.010955 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0103323 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.00983132 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.00953176 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00938477 |
| RAD51B | RAD51 paralog B | 0.00930612 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.00923336 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.00919874 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00869707 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.00851567 |
| KRT81 | keratin 81, type II | 0.00844595 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.00827836 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.00816399 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00810873 |
| MAP1B | microtubule-associated protein 1B | 0.00806893 |
| FNDC3A | fibronectin type III domain containing 3A | 0.00804516 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.00795808 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.00783265 |
| CDK8 | cyclin-dependent kinase 8 | 0.00771904 |
| EFNA5 | ephrin-A5 | 0.00770436 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00752888 |
| SLC39A11 | solute carrier family 39, member 11 | 0.00749748 |
| VEGFC | vascular endothelial growth factor C | 0.00741787 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.00739982 |
| TOX | thymocyte selection-associated high mobility group box | 0.00733877 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.00733323 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.00727365 |
| TNS3 | tensin 3 | 0.00708815 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0070795 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00704502 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0069785 |
| E2F7 | E2F transcription factor 7 | 0.00696426 |
| FOSL1 | FOS-like antigen 1 | 0.0068463 |
| ANKRD30B | ankyrin repeat domain 30B | 0.0067163 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | 0.00670435 |
| FRMD6 | FERM domain containing 6 | 0.00660116 |
| UBE3B | ubiquitin protein ligase E3B | 0.00648657 |
| DCLK2 | doublecortin-like kinase 2 | 0.00642759 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.00638607 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0063772 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.00633282 |
| XRRA1 | X-ray radiation resistance associated 1 | 0.00629763 |
| AIG1 | androgen-induced 1 | 0.00619107 |
| PDE10A | phosphodiesterase 10A | 0.00611845 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.00611307 |
| RRM2 | ribonucleotide reductase M2 | 0.00611199 |
| IPO7 | importin 7 | 0.00610782 |
| CLMP | CXADR-like membrane protein | 0.00608741 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 | 0.00603431 |
| RPL3 | ribosomal protein L3 | 0.0060063 |
| OPHN1 | oligophrenin 1 | 0.00598299 |
| LAMC2 | laminin, gamma 2 | 0.00596075 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00594933 |
| CDK11B | cyclin-dependent kinase 11B | 0.00591137 |
| SLK | STE20-like kinase | 0.0058926 |
| CKAP2L | cytoskeleton associated protein 2-like | 0.00588509 |
| AMPH | amphiphysin | 0.00588176 |
| FGF13 | fibroblast growth factor 13 | 0.00588025 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.00585081 |
| SH3RF3 | SH3 domain containing ring finger 3 | 0.00581557 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.00581447 |
| PRKD1 | protein kinase D1 | 0.00580856 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.00580083 |
| RBM17 | RNA binding motif protein 17 | 0.00578305 |
| IL7R | interleukin 7 receptor | 0.00576199 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.00576139 |
| CCBE1 | collagen and calcium binding EGF domains 1 | 0.00569108 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00568039 |
| IRF2BPL | interferon regulatory factor 2 binding protein-like | 0.00560242 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.00558135 |
| LNPK | lunapark, ER junction formation factor | 0.00555586 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00553854 |
| PGRMC2 | progesterone receptor membrane component 2 | 0.00550996 |
| BAG6 | BCL2-associated athanogene 6 | 0.0055065 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.00550168 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.00546955 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.00540608 |
| DOCK3 | dedicator of cytokinesis 3 | 0.00539749 |
| HDGFL3 | HDGF like 3 | 0.00538422 |
| FBXO7 | F-box protein 7 | 0.00533304 |
| SPON2 | spondin 2, extracellular matrix protein | 0.00532883 |
| MSI2 | musashi RNA-binding protein 2 | 0.00529944 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.318815 |
| TMSB10 | thymosin beta 10 | -0.215562 |
| VIM | vimentin | -0.188094 |
| UBC | ubiquitin C | -0.174683 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.136164 |
| MT2A | metallothionein 2A | -0.111375 |
| AHNAK | AHNAK nucleoprotein | -0.108236 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.10464 |
| LOX | lysyl oxidase | -0.0860448 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0816406 |
| COL3A1 | collagen, type III, alpha 1 | -0.0812463 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0787578 |
| CD44 | CD44 molecule (Indian blood group) | -0.0780767 |
| NDRG1 | N-myc downstream regulated 1 | -0.0757212 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0727859 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0714675 |
| ANXA2 | annexin A2 | -0.0703993 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0688489 |
| CD99 | CD99 molecule | -0.068302 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0663639 |
| LMNA | lamin A/C | -0.0645507 |
| FLNB | filamin B, beta | -0.0640908 |
| LOXL2 | lysyl oxidase-like 2 | -0.0640675 |
| HLA-B | major histocompatibility complex, class I, B | -0.0636326 |
| FBN1 | fibrillin 1 | -0.06114 |
| PTMA | prothymosin, alpha | -0.0597024 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.058992 |
| B2M | beta-2-microglobulin | -0.0575494 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0564598 |
| S100A6 | S100 calcium binding protein A6 | -0.0562699 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0550056 |
| CANX | calnexin | -0.0546742 |
| S100A10 | S100 calcium binding protein A10 | -0.0545331 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0542963 |
| SQSTM1 | sequestosome 1 | -0.0539046 |
| COL5A2 | collagen, type V, alpha 2 | -0.0525999 |
| APP | amyloid beta (A4) precursor protein | -0.0500424 |
| OGA | O-GlcNAcase | -0.0497591 |
| PKM | pyruvate kinase, muscle | -0.0497584 |
| CSTB | cystatin B (stefin B) | -0.0495253 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0469287 |
| PLAT | plasminogen activator, tissue | -0.0459207 |
| COL1A2 | collagen, type I, alpha 2 | -0.0440445 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.041099 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0402992 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0400679 |
| NAV2 | neuron navigator 2 | -0.0400408 |
| RPS27A | ribosomal protein S27a | -0.0398029 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0390705 |
| STC1 | stanniocalcin 1 | -0.038654 |
| CALR | calreticulin | -0.0375912 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0367296 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0357154 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0350685 |
| HDLBP | high density lipoprotein binding protein | -0.0341412 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.033421 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0333407 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0332733 |
| HIP1 | huntingtin interacting protein 1 | -0.0331119 |
| RPL23 | ribosomal protein L23 | -0.0328832 |
| THBS2 | thrombospondin 2 | -0.0328642 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.0325766 |
| HLA-C | major histocompatibility complex, class I, C | -0.0322031 |
| MYADM | myeloid-associated differentiation marker | -0.032073 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0320062 |
| AUTS2 | autism susceptibility candidate 2 | -0.0318153 |
| RRBP1 | ribosome binding protein 1 | -0.0316295 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0316102 |
| HLA-E | major histocompatibility complex, class I, E | -0.0311571 |
| FLNA | filamin A, alpha | -0.0308499 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0308382 |
| MT1X | metallothionein 1X | -0.0307864 |
| RTN4 | reticulon 4 | -0.0305162 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0304489 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0297477 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0297368 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0296544 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0291734 |
| ENO1 | enolase 1, (alpha) | -0.0285009 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.028429 |
| LDHA | lactate dehydrogenase A | -0.0283935 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0279633 |
| GLG1 | golgi glycoprotein 1 | -0.027829 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0274577 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0273374 |
| ACTN4 | actinin, alpha 4 | -0.0272784 |
| PRELID2 | PRELI domain containing 2 | -0.0265442 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.026506 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0263566 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0263539 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0262712 |
| RPL28 | ribosomal protein L28 | -0.0260593 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0256611 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.025356 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.025326 |
| TAGLN2 | transgelin 2 | -0.0252986 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0252682 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0252589 |
| TMSB4X | thymosin beta 4, X-linked | -0.0251291 |
| TAOK1 | TAO kinase 1 | -0.0250001 |
