| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bendamustine perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bendamustine_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0988642 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0823178 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0795009 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0658669 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0656293 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0650454 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0646002 |
| NEK7 | NIMA-related kinase 7 | 0.0597659 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0516517 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.051012 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.04813 |
| KIF5B | kinesin family member 5B | 0.0480244 |
| XPO1 | exportin 1 | 0.0473012 |
| TXNRD1 | thioredoxin reductase 1 | 0.04685 |
| TNPO1 | transportin 1 | 0.0460731 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0439466 |
| ECT2 | epithelial cell transforming 2 | 0.0425797 |
| POTEF | POTE ankyrin domain family, member F | 0.04219 |
| GASK1B | golgi associated kinase 1B | 0.0415846 |
| OXR1 | oxidation resistance 1 | 0.0401621 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0399223 |
| SERINC1 | serine incorporator 1 | 0.0383589 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.037828 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0377243 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0376839 |
| MED13L | mediator complex subunit 13-like | 0.0367591 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0366283 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0364338 |
| IL6ST | interleukin 6 signal transducer | 0.033772 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0336779 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0335387 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0334389 |
| PCBP2 | poly(rC) binding protein 2 | 0.033324 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0329732 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0328972 |
| THOC1 | THO complex 1 | 0.0320413 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0318586 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.031137 |
| SQSTM1 | sequestosome 1 | 0.0310797 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0308168 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0306352 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0304271 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0303887 |
| CENPF | centromere protein F, 350/400kDa | 0.0302813 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0302244 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0299508 |
| ZNF217 | zinc finger protein 217 | 0.0293612 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0290633 |
| CDK17 | cyclin-dependent kinase 17 | 0.028721 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0286225 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0285069 |
| ETNK1 | ethanolamine kinase 1 | 0.028309 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.028296 |
| WDR43 | WD repeat domain 43 | 0.0278159 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0277268 |
| LMO7 | LIM domain 7 | 0.0275078 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0274763 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.0267935 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0267773 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0262063 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0261403 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0260959 |
| RPL3 | ribosomal protein L3 | 0.0260551 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0259904 |
| NCKAP1 | NCK-associated protein 1 | 0.0259228 |
| CLDND1 | claudin domain containing 1 | 0.0257442 |
| CCNL1 | cyclin L1 | 0.0256246 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0255822 |
| EZR | ezrin | 0.0254334 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0250935 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0250182 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0248319 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0245554 |
| CEP70 | centrosomal protein 70kDa | 0.0241344 |
| DSPP | dentin sialophosphoprotein | 0.0236764 |
| HMGB2 | high mobility group box 2 | 0.0235572 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0230584 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0226943 |
| CPOX | coproporphyrinogen oxidase | 0.0226545 |
| HLTF | helicase-like transcription factor | 0.0225724 |
| PUM2 | pumilio RNA-binding family member 2 | 0.022486 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0223948 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0216629 |
| IPMK | inositol polyphosphate multikinase | 0.0213251 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 0.0210065 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0208139 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.020757 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0207145 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0206437 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0206049 |
| RNF145 | ring finger protein 145 | 0.0205832 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0205494 |
| ANLN | anillin, actin binding protein | 0.0205216 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0205073 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0204515 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0203436 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0201226 |
| AFG3L2 | AFG3-like AAA ATPase 2 | 0.0201011 |
| OGA | O-GlcNAcase | 0.0200716 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0199392 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | -0.213415 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.197356 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.177394 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.173379 |
| TMSB10 | thymosin beta 10 | -0.140107 |
| HMGA2 | high mobility group AT-hook 2 | -0.117584 |
| RAB7A | RAB7A, member RAS oncogene family | -0.110463 |
| EHBP1 | EH domain binding protein 1 | -0.0910744 |
| EGR1 | early growth response 1 | -0.0899618 |
| VIM | vimentin | -0.0887632 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0786169 |
| FTL | ferritin, light polypeptide | -0.0783934 |
| ACTG1 | actin gamma 1 | -0.073537 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0697448 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0674547 |
| PCDH7 | protocadherin 7 | -0.0643359 |
| JMJD1C | jumonji domain containing 1C | -0.0643159 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0631351 |
| RPL35A | ribosomal protein L35a | -0.0624251 |
| ADIPOR2 | adiponectin receptor 2 | -0.0622917 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0577942 |
| NHSL1 | NHS-like 1 | -0.0575248 |
| MMP12 | matrix metallopeptidase 12 | -0.0560872 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0559928 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0557152 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0542707 |
| RPL37A | ribosomal protein L37a | -0.0524543 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0520646 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0512617 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0497537 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0491648 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0488216 |
| AREG | amphiregulin | -0.0487987 |
| CMIP | c-Maf inducing protein | -0.0486529 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0486173 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0485364 |
| INTS6 | integrator complex subunit 6 | -0.0479284 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0450355 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.043418 |
| RASAL2 | RAS protein activator like 2 | -0.0421346 |
| CUX1 | cut-like homeobox 1 | -0.0416696 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0415049 |
| ZNF638 | zinc finger protein 638 | -0.0412418 |
| BPTF | bromodomain PHD finger transcription factor | -0.0410026 |
| LRRC23 | leucine rich repeat containing 23 | -0.0409877 |
| YAP1 | Yes-associated protein 1 | -0.0408158 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0407176 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0405423 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0404598 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0393275 |
| DTNA | dystrobrevin, alpha | -0.0389685 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0382287 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0380562 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0375084 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.037485 |
| ASPH | aspartate beta-hydroxylase | -0.0373263 |
| HMGA1 | high mobility group AT-hook 1 | -0.0372633 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0367767 |
| RPS8 | ribosomal protein S8 | -0.0363343 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.03574 |
| RPS6 | ribosomal protein S6 | -0.0353643 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0352824 |
| CANX | calnexin | -0.0352408 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0351812 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.034702 |
| R3HDM2 | R3H domain containing 2 | -0.034313 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0341126 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0338752 |
| TBCA | tubulin folding cofactor A | -0.0334413 |
| NF1 | neurofibromin 1 | -0.0332865 |
| TPM4 | tropomyosin 4 | -0.0329607 |
| ZNF804A | zinc finger protein 804A | -0.03258 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0323274 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0317433 |
| GNAS | GNAS complex locus | -0.0316394 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.031338 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0312539 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.031181 |
| HDAC9 | histone deacetylase 9 | -0.0305423 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0303814 |
| DTNB | dystrobrevin, beta | -0.0302677 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0301601 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0301331 |
| USP34 | ubiquitin specific peptidase 34 | -0.0300175 |
| VMP1 | vacuole membrane protein 1 | -0.0299599 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0298602 |
| RPS12 | ribosomal protein S12 | -0.0296948 |
| H1-0 | H1.0 linker histone | -0.029608 |
| NAV3 | neuron navigator 3 | -0.0295456 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.029398 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0293306 |
| NEBL | nebulette | -0.0285729 |
| KSR2 | kinase suppressor of ras 2 | -0.0283876 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0279431 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0278412 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0278194 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0277938 |
| RPS19 | ribosomal protein S19 | -0.0271406 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0271391 |
| JUN | jun proto-oncogene | -0.0269533 |
