| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bendamustine perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bendamustine_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.152197 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.12381 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0924825 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0732705 |
| RNF43 | ring finger protein 43 | 0.0540133 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0534228 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0519285 |
| PRELID2 | PRELI domain containing 2 | 0.0491837 |
| IFNGR1 | interferon gamma receptor 1 | 0.0485964 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0471335 |
| CANX | calnexin | 0.0446611 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0443142 |
| RUNX1 | runt-related transcription factor 1 | 0.043886 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0431535 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.04168 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0391839 |
| PHF3 | PHD finger protein 3 | 0.0365912 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0365243 |
| HDLBP | high density lipoprotein binding protein | 0.0349849 |
| COG6 | component of oligomeric golgi complex 6 | 0.0347811 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0343403 |
| CALR | calreticulin | 0.0341823 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0337167 |
| FAT1 | FAT atypical cadherin 1 | 0.0331906 |
| TXNIP | thioredoxin interacting protein | 0.0331451 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0326152 |
| SEC24D | SEC24 family member D | 0.0318228 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0310852 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0310351 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0309741 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0302949 |
| GOLGB1 | golgin B1 | 0.0292623 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0291164 |
| PGK1 | phosphoglycerate kinase 1 | 0.0290975 |
| UBAC2 | UBA domain containing 2 | 0.0289839 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0286109 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0278997 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0278199 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0277639 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0274635 |
| EHF | ets homologous factor | 0.0274118 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0273455 |
| AHNAK | AHNAK nucleoprotein | 0.0272071 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.026913 |
| AHI1 | Abelson helper integration site 1 | 0.0263869 |
| GOLGA2 | golgin A2 | 0.0256735 |
| AOPEP | aminopeptidase O (putative) | 0.0256256 |
| ERCC5 | excision repair cross-complementation group 5 | 0.02548 |
| COPA | coatomer protein complex, subunit alpha | 0.0249598 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | 0.0249353 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0249162 |
| RNF149 | ring finger protein 149 | 0.0247743 |
| PTEN | phosphatase and tensin homolog | 0.0243695 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0242485 |
| USP3 | ubiquitin specific peptidase 3 | 0.0239897 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0238994 |
| OGA | O-GlcNAcase | 0.023661 |
| ENO1 | enolase 1, (alpha) | 0.0236056 |
| NEBL | nebulette | 0.0232201 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0230183 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0229916 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0229553 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0226366 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0226113 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0224015 |
| HELZ | helicase with zinc finger | 0.0221564 |
| HYOU1 | hypoxia up-regulated 1 | 0.0221175 |
| USPL1 | ubiquitin specific peptidase like 1 | 0.021896 |
| GOLGA4 | golgin A4 | 0.0211465 |
| SSR1 | signal sequence receptor, alpha | 0.0209579 |
| MEIS2 | Meis homeobox 2 | 0.0208017 |
| UBL3 | ubiquitin-like 3 | 0.0207736 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0207687 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0207353 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0204807 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0204241 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0203344 |
| ZNF148 | zinc finger protein 148 | 0.0202117 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0202017 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0200298 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0200141 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0194157 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0194095 |
| RNF145 | ring finger protein 145 | 0.0192436 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0191731 |
| SUCO | SUN domain containing ossification factor | 0.0190051 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.018891 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0187998 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.0187283 |
| HGD | homogentisate 1,2-dioxygenase | 0.0183331 |
| DENND4C | DENN/MADD domain containing 4C | 0.0182912 |
| METTL15 | methyltransferase like 15 | 0.0182647 |
| IL20RA | interleukin 20 receptor, alpha | 0.0181885 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0181025 |
| GRAMD2B | GRAM domain containing 2B | 0.018093 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0179207 |
| YEATS2 | YEATS domain containing 2 | 0.017882 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0178787 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0178238 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0177832 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RNF213 | ring finger protein 213 | -0.168181 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.161508 |
| EGR1 | early growth response 1 | -0.161465 |
| ANXA2 | annexin A2 | -0.157956 |
| VCL | vinculin | -0.147773 |
| LMO7 | LIM domain 7 | -0.135893 |
| MACC1 | metastasis associated in colon cancer 1 | -0.11297 |
| RIGI | RNA sensor RIG-I | -0.112378 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.108639 |
| AREG | amphiregulin | -0.106448 |
| SP100 | SP100 nuclear antigen | -0.104477 |
| RAB7A | RAB7A, member RAS oncogene family | -0.104072 |
| INTS6 | integrator complex subunit 6 | -0.101721 |
| MX1 | MX dynamin-like GTPase 1 | -0.0980312 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0949005 |
| ERBIN | erbb2 interacting protein | -0.0945931 |
| TJP1 | tight junction protein 1 | -0.0868673 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0867814 |
| MX2 | MX dynamin-like GTPase 2 | -0.0865729 |
| MYO1E | myosin IE | -0.0835403 |
| PLSCR1 | phospholipid scramblase 1 | -0.082557 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0824089 |
| EZR | ezrin | -0.0797517 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0773876 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0758825 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0750912 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0750251 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0749136 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0701844 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0684735 |
| B2M | beta-2-microglobulin | -0.0650202 |
| CCNL1 | cyclin L1 | -0.0645765 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0639355 |
| VMP1 | vacuole membrane protein 1 | -0.0586024 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0584893 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0577651 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.054783 |
| ZNF292 | zinc finger protein 292 | -0.0539253 |
| JUN | jun proto-oncogene | -0.0528385 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0527264 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0523251 |
| EFNB2 | ephrin-B2 | -0.0515297 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0511572 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0484061 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0481183 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0480849 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0476579 |
| PERP | PERP, TP53 apoptosis effector | -0.0463886 |
| PTMA | prothymosin, alpha | -0.0461931 |
| BCL2L1 | BCL2-like 1 | -0.0452314 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0450422 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0449433 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0439935 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0439253 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0437934 |
| XAF1 | XIAP associated factor 1 | -0.0436801 |
| ITGA6 | integrin, alpha 6 | -0.0435456 |
| MCL1 | myeloid cell leukemia 1 | -0.0426349 |
| LYZ | lysozyme | -0.0423469 |
| PMP22 | peripheral myelin protein 22 | -0.0422857 |
| LCN2 | lipocalin 2 | -0.0412298 |
| TMC5 | transmembrane channel-like 5 | -0.0408326 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0408228 |
| TNS4 | tensin 4 | -0.0402543 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0398893 |
| KLF6 | Kruppel-like factor 6 | -0.0397039 |
| NABP1 | nucleic acid binding protein 1 | -0.0392354 |
| TMSB10 | thymosin beta 10 | -0.0392337 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0392295 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0391408 |
| UBAP2 | ubiquitin associated protein 2 | -0.0388565 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0383674 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0381853 |
| SQSTM1 | sequestosome 1 | -0.0377046 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0375393 |
| LAMA4 | laminin, alpha 4 | -0.0370761 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0368167 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0366057 |
| SPATA13 | spermatogenesis associated 13 | -0.0359186 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0358195 |
| DGKH | diacylglycerol kinase, eta | -0.035261 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0345751 |
| TUFT1 | tuftelin 1 | -0.034496 |
| MAP7 | microtubule-associated protein 7 | -0.0341783 |
| DUSP10 | dual specificity phosphatase 10 | -0.0340092 |
| CLDN4 | claudin 4 | -0.0338613 |
| FOSL1 | FOS-like antigen 1 | -0.0331932 |
| ACTG1 | actin gamma 1 | -0.0326273 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0325365 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0324606 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0323667 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0322457 |
| PRKCA | protein kinase C, alpha | -0.0320769 |
| PLAUR | plasminogen activator, urokinase receptor | -0.031837 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0317668 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.031667 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0313316 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0313208 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0308729 |
| IRS2 | insulin receptor substrate 2 | -0.0307478 |