| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bendamustine perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bendamustine_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.1176 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0804804 |
| TES | testin LIM domain protein | 0.0779982 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0602144 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0559559 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0556208 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0513455 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0482206 |
| ARF4 | ADP-ribosylation factor 4 | 0.0460897 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0457228 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0455073 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0452278 |
| KRT17 | keratin 17, type I | 0.044777 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0429872 |
| PTMA | prothymosin, alpha | 0.0410257 |
| PCBP2 | poly(rC) binding protein 2 | 0.040855 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0375899 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0374382 |
| HM13 | histocompatibility (minor) 13 | 0.036155 |
| AREG | amphiregulin | 0.0361236 |
| TOP1 | topoisomerase (DNA) I | 0.0352638 |
| CALR | calreticulin | 0.0341907 |
| POTEF | POTE ankyrin domain family, member F | 0.0339038 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0337798 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0327038 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0318636 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0312895 |
| GOLGA4 | golgin A4 | 0.0307481 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0303464 |
| XPO1 | exportin 1 | 0.0302521 |
| FAM13A | family with sequence similarity 13, member A | 0.0302077 |
| RBM39 | RNA binding motif protein 39 | 0.0301963 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0300322 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0300281 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0297868 |
| DSTN | destrin (actin depolymerizing factor) | 0.0293314 |
| MATR3 | matrin 3 | 0.0285083 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0282235 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0281969 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.027778 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0271669 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0270537 |
| HYOU1 | hypoxia up-regulated 1 | 0.0269792 |
| HBP1 | HMG-box transcription factor 1 | 0.0269228 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0264984 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0263525 |
| LYZ | lysozyme | 0.0260804 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0260451 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0258608 |
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.0255754 |
| SLMAP | sarcolemma associated protein | 0.0250922 |
| SRPRA | SRP receptor subunit alpha | 0.0250508 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.0250287 |
| NUP58 | nucleoporin 58 | 0.0249424 |
| HELZ | helicase with zinc finger | 0.0248853 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0248729 |
| SEPTIN2 | septin 2 | 0.0246413 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0245432 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.024509 |
| LAMB3 | laminin, beta 3 | 0.0243957 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0243838 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0243428 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0241 |
| AFTPH | aftiphilin | 0.0240628 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.023748 |
| SNX13 | sorting nexin 13 | 0.0237424 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.023703 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0236657 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0236095 |
| SRP54 | signal recognition particle 54kDa | 0.0231802 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0228687 |
| ENO1 | enolase 1, (alpha) | 0.0228589 |
| SET | SET nuclear proto-oncogene | 0.0227801 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0227253 |
| PREPL | prolyl endopeptidase-like | 0.0225837 |
| RPLP0 | ribosomal protein, large, P0 | 0.0224389 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0223702 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0222134 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.021988 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0219329 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0218152 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0217543 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0215445 |
| OGA | O-GlcNAcase | 0.0214428 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0207588 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0200695 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0200407 |
| ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 | 0.0198673 |
| SMAP1 | small ArfGAP 1 | 0.0197962 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0197859 |
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | 0.0196283 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0196276 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0195971 |
| SERINC1 | serine incorporator 1 | 0.0195836 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0195473 |
| TCP1 | t-complex 1 | 0.0193788 |
| KLHL24 | kelch-like family member 24 | 0.019325 |
| FTL | ferritin, light polypeptide | 0.0193021 |
| CCNY | cyclin Y | 0.0191991 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0191889 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | -0.308107 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.127239 |
| LMO7 | LIM domain 7 | -0.119379 |
| TMC5 | transmembrane channel-like 5 | -0.111132 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0916772 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.081164 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0783715 |
| NPSR1 | neuropeptide S receptor 1 | -0.0771571 |
| EHBP1 | EH domain binding protein 1 | -0.0770034 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0655684 |
| EMP1 | epithelial membrane protein 1 | -0.0645289 |
| TMSB10 | thymosin beta 10 | -0.0600577 |
| CD2AP | CD2-associated protein | -0.0578921 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0578523 |
| RRBP1 | ribosome binding protein 1 | -0.0575051 |
| RNF213 | ring finger protein 213 | -0.0571614 |
| ASPH | aspartate beta-hydroxylase | -0.0546492 |
| MKI67 | marker of proliferation Ki-67 | -0.0516617 |
| H1-0 | H1.0 linker histone | -0.0503021 |
| ACTN4 | actinin, alpha 4 | -0.0485887 |
| TMEM45B | transmembrane protein 45B | -0.0466303 |
| SEPTIN9 | septin 9 | -0.0458946 |
| FLNB | filamin B, beta | -0.0458657 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0450251 |
| ANXA2 | annexin A2 | -0.0434002 |
| BPTF | bromodomain PHD finger transcription factor | -0.0425072 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0412475 |
| WWC1 | WW and C2 domain containing 1 | -0.0407554 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0400317 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0385793 |
| RPL26 | ribosomal protein L26 | -0.0383893 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0377745 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0376592 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0373419 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0365663 |
| ETV6 | ets variant 6 | -0.0365158 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0363928 |
| PLSCR1 | phospholipid scramblase 1 | -0.03615 |
| MCU | mitochondrial calcium uniporter | -0.0356092 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0346968 |
| PRSS3 | protease, serine, 3 | -0.0346882 |
| RPL37A | ribosomal protein L37a | -0.0345996 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0343437 |
| FAT1 | FAT atypical cadherin 1 | -0.0341077 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0336089 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0335618 |
| COBL | cordon-bleu WH2 repeat protein | -0.0335609 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0334981 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0329034 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.032851 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0327543 |
| PRKCA | protein kinase C, alpha | -0.03273 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.032427 |
| B2M | beta-2-microglobulin | -0.0323788 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0323408 |
| ATP11A | ATPase, class VI, type 11A | -0.0322569 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0322412 |
| THOC2 | THO complex 2 | -0.0319863 |
| TMEM123 | transmembrane protein 123 | -0.0319771 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0317923 |
| EPCAM | epithelial cell adhesion molecule | -0.0311042 |
| MECOM | MDS1 and EVI1 complex locus | -0.0308732 |
| BCL2L1 | BCL2-like 1 | -0.0308195 |
| PHF14 | PHD finger protein 14 | -0.0307011 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.030544 |
| MYO1E | myosin IE | -0.0304761 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0304514 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0304509 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0301948 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0300944 |
| AOPEP | aminopeptidase O (putative) | -0.0299801 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0294666 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.029377 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0292593 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0289233 |
| CCDC146 | coiled-coil domain containing 146 | -0.0287488 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0286624 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0279049 |
| SHROOM3 | shroom family member 3 | -0.027849 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0278247 |
| RPS2 | ribosomal protein S2 | -0.027788 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0276511 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0276093 |
| ONECUT3 | one cut homeobox 3 | -0.0275889 |
| AHNAK | AHNAK nucleoprotein | -0.0275626 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0270244 |
| CDK6 | cyclin-dependent kinase 6 | -0.0267553 |
| S100A10 | S100 calcium binding protein A10 | -0.0265109 |
| TCF12 | transcription factor 12 | -0.0264648 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0264549 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0263367 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.02616 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0260717 |
| RPLP1 | ribosomal protein, large, P1 | -0.0259735 |
| RPS21 | ribosomal protein S21 | -0.0258563 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0258541 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0257754 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0257272 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0257082 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0256726 |
