| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bendamustine perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bendamustine_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.100922 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.098569 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0943485 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0883325 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0777779 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0699751 |
| PTMA | prothymosin, alpha | 0.0665431 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.065772 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0651998 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0628033 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0625902 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0597463 |
| RBM39 | RNA binding motif protein 39 | 0.0585898 |
| EREG | epiregulin | 0.0557271 |
| RNF145 | ring finger protein 145 | 0.0547304 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0500207 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0477614 |
| RPL12 | ribosomal protein L12 | 0.0467124 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0464876 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0462377 |
| RPS12 | ribosomal protein S12 | 0.0461834 |
| ATF4 | activating transcription factor 4 | 0.0452522 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0439861 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0424286 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0421461 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.041991 |
| B2M | beta-2-microglobulin | 0.0419122 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0417907 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0410101 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0408752 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0405765 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0387835 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0386883 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0386209 |
| MLEC | malectin | 0.0379519 |
| HMGB2 | high mobility group box 2 | 0.0378458 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0378448 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0373327 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0371663 |
| S100P | S100 calcium binding protein P | 0.0371068 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0368552 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0368401 |
| KIF5B | kinesin family member 5B | 0.0366262 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.035953 |
| SLMAP | sarcolemma associated protein | 0.0354136 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0350119 |
| KRT18 | keratin 18, type I | 0.0348087 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0346111 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.034454 |
| GDF15 | growth differentiation factor 15 | 0.0339354 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0338749 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0337571 |
| TOP1 | topoisomerase (DNA) I | 0.0335118 |
| CALR | calreticulin | 0.0333207 |
| RPL3 | ribosomal protein L3 | 0.0329604 |
| NCKAP1 | NCK-associated protein 1 | 0.0327539 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0327446 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0326186 |
| YME1L1 | YME1-like 1 ATPase | 0.032441 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0320625 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0319511 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0310876 |
| RPL23 | ribosomal protein L23 | 0.0310438 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0307771 |
| CCNL1 | cyclin L1 | 0.0307673 |
| TPM3 | tropomyosin 3 | 0.0306381 |
| GOLGA4 | golgin A4 | 0.0305374 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0302006 |
| WDR43 | WD repeat domain 43 | 0.0294377 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0293578 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0293356 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0292962 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0292646 |
| MATR3 | matrin 3 | 0.0290823 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0288732 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0286072 |
| YTHDC1 | YTH domain containing 1 | 0.0281854 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0280372 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0279972 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0279952 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0278786 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0276178 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0271555 |
| NOP58 | NOP58 ribonucleoprotein | 0.0270474 |
| NUP58 | nucleoporin 58 | 0.0265966 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0264244 |
| PNN | pinin, desmosome associated protein | 0.0262943 |
| OGA | O-GlcNAcase | 0.0262307 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0262057 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0261783 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0260835 |
| TFG | TRK-fused gene | 0.0260758 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0260579 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0260333 |
| TES | testin LIM domain protein | 0.0249952 |
| VCL | vinculin | 0.0249589 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0249358 |
| SERINC1 | serine incorporator 1 | 0.024929 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0248035 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.024778 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.320049 |
| NDRG1 | N-myc downstream regulated 1 | -0.126449 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.123321 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.107205 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.10239 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0957086 |
| ITGA6 | integrin, alpha 6 | -0.0837758 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.083239 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0823617 |
| NPSR1 | neuropeptide S receptor 1 | -0.0800864 |
| MYO1E | myosin IE | -0.0707787 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0699815 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0686228 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0655995 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0645477 |
| FLNB | filamin B, beta | -0.0643735 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0635373 |
| TNS4 | tensin 4 | -0.0610686 |
| ACTG1 | actin gamma 1 | -0.0591995 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0590021 |
| TXNIP | thioredoxin interacting protein | -0.0584204 |
| MT2A | metallothionein 2A | -0.0563016 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0544637 |
| PRSS3 | protease, serine, 3 | -0.0520035 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0510073 |
| ONECUT3 | one cut homeobox 3 | -0.0505502 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0499204 |
| FHIT | fragile histidine triad | -0.0498367 |
| AHNAK | AHNAK nucleoprotein | -0.0493638 |
| H1-0 | H1.0 linker histone | -0.048442 |
| CADPS | Ca++-dependent secretion activator | -0.0457742 |
| ITGB4 | integrin, beta 4 | -0.0450661 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0438681 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0433914 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0420671 |
| ANXA2 | annexin A2 | -0.0409198 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0405269 |
| MUC17 | mucin 17, cell surface associated | -0.0398706 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0398488 |
| ABHD2 | abhydrolase domain containing 2 | -0.0397454 |
| RPS6 | ribosomal protein S6 | -0.038931 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.0385696 |
| NFIA | nuclear factor I/A | -0.0385593 |
| RNF43 | ring finger protein 43 | -0.0385443 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.038199 |
| AGR2 | anterior gradient 2 | -0.037332 |
| SMYD3 | SET and MYND domain containing 3 | -0.0369622 |
| ACTN4 | actinin, alpha 4 | -0.0368195 |
| FAT1 | FAT atypical cadherin 1 | -0.0366028 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0365902 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0364066 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0350781 |
| RAD51B | RAD51 paralog B | -0.0349145 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0348218 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0346292 |
| SH3D19 | SH3 domain containing 19 | -0.0342823 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0335748 |
| FOXP1 | forkhead box P1 | -0.03345 |
| DIAPH2 | diaphanous-related formin 2 | -0.0329687 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0329623 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0323692 |
| PTEN | phosphatase and tensin homolog | -0.0322921 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0318936 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0317856 |
| ATXN1 | ataxin 1 | -0.0313257 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0308886 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0308396 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0303631 |
| MED13 | mediator complex subunit 13 | -0.0302821 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0298809 |
| DEK | DEK proto-oncogene | -0.0296623 |
| NEBL | nebulette | -0.0296574 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0291873 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0291623 |
| ABLIM1 | actin binding LIM protein 1 | -0.0289172 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0288196 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0285261 |
| PKP2 | plakophilin 2 | -0.0281098 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0280189 |
| SNX9 | sorting nexin 9 | -0.0279121 |
| MT1X | metallothionein 1X | -0.0278514 |
| AUTS2 | autism susceptibility candidate 2 | -0.027559 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.027397 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0271617 |
| MUC13 | mucin 13, cell surface associated | -0.0270437 |
| CCND1 | cyclin D1 | -0.0268457 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0266727 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0265682 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0264718 |
| RPL34 | ribosomal protein L34 | -0.0263378 |
| PIGR | polymeric immunoglobulin receptor | -0.0261426 |
| CLOCK | clock circadian regulator | -0.0260474 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0259634 |
| CMIP | c-Maf inducing protein | -0.0259421 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.0258734 |
| BPTF | bromodomain PHD finger transcription factor | -0.0258237 |
| S100A6 | S100 calcium binding protein A6 | -0.0257475 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0257087 |
| FERMT1 | fermitin family member 1 | -0.0256513 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0256178 |
