| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bendamustine perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bendamustine_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.147301 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.130644 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.121054 |
| POTEF | POTE ankyrin domain family, member F | 0.105429 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0655552 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0619601 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0565203 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0558356 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0465769 |
| MATR3 | matrin 3 | 0.0450191 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0440264 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0440143 |
| WAC | WW domain containing adaptor with coiled-coil | 0.043039 |
| NUP58 | nucleoporin 58 | 0.0380862 |
| WDR43 | WD repeat domain 43 | 0.0365655 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0356541 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.032999 |
| PCBP2 | poly(rC) binding protein 2 | 0.0329414 |
| HMGB2 | high mobility group box 2 | 0.0327123 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0327117 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0320008 |
| SET | SET nuclear proto-oncogene | 0.0304675 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0301683 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0298371 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0298149 |
| XPO1 | exportin 1 | 0.0295487 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0294226 |
| ENO1 | enolase 1, (alpha) | 0.0292057 |
| TOP1 | topoisomerase (DNA) I | 0.0287691 |
| RBM39 | RNA binding motif protein 39 | 0.0276581 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0272797 |
| QKI | QKI, KH domain containing, RNA binding | 0.0272129 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0264684 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0263731 |
| TFG | TRK-fused gene | 0.0262157 |
| RPLP0 | ribosomal protein, large, P0 | 0.0253609 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0253259 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.025183 |
| RNF145 | ring finger protein 145 | 0.0249908 |
| ECT2 | epithelial cell transforming 2 | 0.0248892 |
| RBM25 | RNA binding motif protein 25 | 0.024067 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0240149 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0237933 |
| OGA | O-GlcNAcase | 0.0236279 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0236227 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0232432 |
| TFRC | transferrin receptor | 0.0231626 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0228174 |
| PER1 | period circadian clock 1 | 0.0223425 |
| CRY1 | cryptochrome circadian clock 1 | 0.0221748 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0219757 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.02183 |
| OLA1 | Obg-like ATPase 1 | 0.0218282 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0217847 |
| UBQLN1 | ubiquilin 1 | 0.0216431 |
| NCKAP1 | NCK-associated protein 1 | 0.0216321 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0216151 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0209503 |
| ATP13A3 | ATPase type 13A3 | 0.0206381 |
| ARF6 | ADP-ribosylation factor 6 | 0.0204585 |
| WDR45B | WD repeat domain 45B | 0.0203819 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0202252 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0201692 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0199313 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0198484 |
| HBP1 | HMG-box transcription factor 1 | 0.0198114 |
| CDC73 | cell division cycle 73 | 0.0198029 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0195971 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0195326 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0194417 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0194249 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.019401 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0193128 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0192312 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0191442 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0190209 |
| ENAH | enabled homolog (Drosophila) | 0.0189059 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0188055 |
| MEMO1 | mediator of cell motility 1 | 0.0183367 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.018327 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0181272 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0180133 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0178919 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0178261 |
| TMSB4X | thymosin beta 4, X-linked | 0.0177086 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.017681 |
| CALR | calreticulin | 0.017425 |
| HELZ | helicase with zinc finger | 0.0172552 |
| RPL35A | ribosomal protein L35a | 0.0168919 |
| NEK7 | NIMA-related kinase 7 | 0.0168666 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0168258 |
| PRPF39 | pre-mRNA processing factor 39 | 0.0168121 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0165261 |
| RPL3 | ribosomal protein L3 | 0.0164398 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0164385 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0163267 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0161611 |
| TPX2 | TPX2, microtubule-associated | 0.0161114 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0159981 |
| WBP11 | WW domain binding protein 11 | 0.0159857 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.198216 |
| MT2A | metallothionein 2A | -0.188991 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.173757 |
| VIM | vimentin | -0.118226 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.113384 |
| TP63 | tumor protein p63 | -0.11277 |
| TXNRD1 | thioredoxin reductase 1 | -0.0966443 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.094578 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0941014 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0809124 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.080301 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0790292 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0777652 |
| CD44 | CD44 molecule (Indian blood group) | -0.0765767 |
| TMSB10 | thymosin beta 10 | -0.0758254 |
| RAI1 | retinoic acid induced 1 | -0.0721664 |
| EHBP1 | EH domain binding protein 1 | -0.0677142 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0637188 |
| FMNL2 | formin-like 2 | -0.0607534 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0590886 |
| ANGPTL4 | angiopoietin-like 4 | -0.0564914 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0561072 |
| SLC38A2 | solute carrier family 38, member 2 | -0.056046 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0547474 |
| USP34 | ubiquitin specific peptidase 34 | -0.0541548 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0532612 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0532063 |
| RUNX1 | runt-related transcription factor 1 | -0.0525746 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0505856 |
| CMIP | c-Maf inducing protein | -0.0504505 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0501971 |
| MT1E | metallothionein 1E | -0.0500351 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0489887 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0482635 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0465076 |
| EGR1 | early growth response 1 | -0.0455614 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0448756 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.044755 |
| LOXL2 | lysyl oxidase-like 2 | -0.0441595 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0423663 |
| HDAC9 | histone deacetylase 9 | -0.042204 |
| YEATS2 | YEATS domain containing 2 | -0.0409817 |
| MT1X | metallothionein 1X | -0.0406564 |
| HMGA1 | high mobility group AT-hook 1 | -0.0403251 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0395789 |
| JMJD1C | jumonji domain containing 1C | -0.0395108 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0393708 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0392631 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0391896 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.039055 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0372956 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0366736 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0362521 |
| HLA-B | major histocompatibility complex, class I, B | -0.0360877 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0359023 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0358492 |
| EXOC4 | exocyst complex component 4 | -0.0356296 |
| BPTF | bromodomain PHD finger transcription factor | -0.0351673 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.034728 |
| PDE10A | phosphodiesterase 10A | -0.0346041 |
| FLNB | filamin B, beta | -0.0342624 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0336624 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0335015 |
| VMP1 | vacuole membrane protein 1 | -0.0330687 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0326804 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0326266 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0325741 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0321298 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0317196 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0314488 |
| PYGL | phosphorylase, glycogen, liver | -0.0314267 |
| AHNAK | AHNAK nucleoprotein | -0.0308415 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0305619 |
| SMYD3 | SET and MYND domain containing 3 | -0.030557 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0305538 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0305425 |
| EMP1 | epithelial membrane protein 1 | -0.0304657 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0301543 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0300314 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0298801 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0297147 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0295849 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0294765 |
| NAV2 | neuron navigator 2 | -0.0292912 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.029076 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0290558 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0289434 |
| FBXO11 | F-box protein 11 | -0.0288127 |
| RAD51B | RAD51 paralog B | -0.0278522 |
| CAPRIN2 | caprin family member 2 | -0.0277543 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.027285 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0270335 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0270192 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0266423 |
| JUN | jun proto-oncogene | -0.0265869 |
| RPL37A | ribosomal protein L37a | -0.0264802 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0264221 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0261264 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0261025 |
| POM121C | POM121 transmembrane nucleoporin C | -0.0260933 |
