| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bendamustine perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bendamustine_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.157739 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.119756 |
| TXNRD1 | thioredoxin reductase 1 | 0.0804892 |
| PGK1 | phosphoglycerate kinase 1 | 0.0789573 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0785637 |
| ASPH | aspartate beta-hydroxylase | 0.0710777 |
| ENO1 | enolase 1, (alpha) | 0.0655954 |
| TOP1 | topoisomerase (DNA) I | 0.063808 |
| SMAD3 | SMAD family member 3 | 0.0600017 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0598435 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0592082 |
| RNF145 | ring finger protein 145 | 0.0591939 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0558951 |
| ATP13A3 | ATPase type 13A3 | 0.0535651 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0526496 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0523495 |
| UVRAG | UV radiation resistance associated | 0.0520671 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0506681 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0494318 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0490542 |
| LAMC2 | laminin, gamma 2 | 0.0484099 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0481966 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0478771 |
| FAM13A | family with sequence similarity 13, member A | 0.0478634 |
| NCKAP1 | NCK-associated protein 1 | 0.0471631 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0466579 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.046636 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.046591 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0452674 |
| PTMA | prothymosin, alpha | 0.0442041 |
| HELZ | helicase with zinc finger | 0.0437041 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0428246 |
| LDHA | lactate dehydrogenase A | 0.0426226 |
| PUM2 | pumilio RNA-binding family member 2 | 0.041461 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0408224 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0405415 |
| PCBP2 | poly(rC) binding protein 2 | 0.0405204 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0392913 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0378773 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.037808 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0375854 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0368466 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0366016 |
| LAMB3 | laminin, beta 3 | 0.036504 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0362447 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0362343 |
| ARRDC3 | arrestin domain containing 3 | 0.0355614 |
| MATR3 | matrin 3 | 0.0347678 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0346897 |
| KRT18 | keratin 18, type I | 0.0345967 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0343297 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0337923 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0335975 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0331011 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0328284 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.032798 |
| UBC | ubiquitin C | 0.0324422 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0324091 |
| SLMAP | sarcolemma associated protein | 0.0314534 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0310405 |
| RASA2 | RAS p21 protein activator 2 | 0.0310223 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0308147 |
| GRAMD1B | GRAM domain containing 1B | 0.030729 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0305419 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0302313 |
| TPD52 | tumor protein D52 | 0.0297711 |
| CDCP1 | CUB domain containing protein 1 | 0.0297328 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0293821 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0292362 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0291093 |
| POTEF | POTE ankyrin domain family, member F | 0.0289564 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0283816 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0283567 |
| KRT7 | keratin 7, type II | 0.0282545 |
| NBAS | neuroblastoma amplified sequence | 0.0280296 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0277758 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0277189 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0275983 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0273623 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0272137 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0271755 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0271127 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0268435 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0267161 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0266891 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0263814 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0263757 |
| DENND4A | DENN/MADD domain containing 4A | 0.0263711 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0262135 |
| ANXA5 | annexin A5 | 0.0260321 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0260319 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0258898 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0257342 |
| NUP58 | nucleoporin 58 | 0.0253224 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0250268 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0248226 |
| APP | amyloid beta (A4) precursor protein | 0.0246061 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.024536 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0244923 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0244696 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | -0.161835 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.151537 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.120691 |
| EGR1 | early growth response 1 | -0.104995 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0919243 |
| NDRG1 | N-myc downstream regulated 1 | -0.0712825 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0710384 |
| MT2A | metallothionein 2A | -0.0665596 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0638544 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0604763 |
| NABP1 | nucleic acid binding protein 1 | -0.0557588 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.052184 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0501139 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0490403 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0486986 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0481391 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0464964 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0451549 |
| INTS6 | integrator complex subunit 6 | -0.041631 |
| JMJD1C | jumonji domain containing 1C | -0.0381748 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0366583 |
| MYO1E | myosin IE | -0.0361169 |
| AGO2 | argonaute RISC catalytic component 2 | -0.035532 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0340762 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0331864 |
| CCNL1 | cyclin L1 | -0.0318926 |
| SYAP1 | synapse associated protein 1 | -0.0315879 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0305142 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0298469 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0292929 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0288993 |
| RAP2B | RAP2B, member of RAS oncogene family | -0.0282628 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0279683 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.027875 |
| VMP1 | vacuole membrane protein 1 | -0.0278197 |
| NBEAL1 | neurobeachin-like 1 | -0.0269444 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0269353 |
| MGAT4C | MGAT4 family, member C | -0.026699 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0264747 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0264434 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0264249 |
| LAMA4 | laminin, alpha 4 | -0.0262044 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0257077 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.025538 |
| VCL | vinculin | -0.025189 |
| GOLGB1 | golgin B1 | -0.0249771 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0240058 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0238579 |
| RNF213 | ring finger protein 213 | -0.0237178 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | -0.0234805 |
| TJP1 | tight junction protein 1 | -0.0230975 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0230348 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0226637 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.0223808 |
| BPTF | bromodomain PHD finger transcription factor | -0.0207816 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0206836 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0206378 |
| EFNA5 | ephrin-A5 | -0.0202165 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0202111 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0198993 |
| MCL1 | myeloid cell leukemia 1 | -0.0193376 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0192822 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0190402 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | -0.0185325 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0183373 |
| ARF4 | ADP-ribosylation factor 4 | -0.0183083 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0180793 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0178658 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0178497 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0178101 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0177565 |
| FAAH2 | fatty acid amide hydrolase 2 | -0.017709 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | -0.01749 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0174253 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0172146 |
| EMP1 | epithelial membrane protein 1 | -0.0170566 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0168458 |
| OCLN | occludin | -0.0164275 |
| OXSR1 | oxidative stress responsive 1 | -0.016358 |
| PER2 | period circadian clock 2 | -0.0162996 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0162322 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0160258 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0159587 |
| PCNX4 | pecanex 4 | -0.0159036 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0155835 |
| ATXN1 | ataxin 1 | -0.0155319 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0154774 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides | -0.0154551 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0154036 |
| FAM193A | family with sequence similarity 193, member A | -0.0154026 |
| OFD1 | oral-facial-digital syndrome 1 | -0.0153816 |
| TRIM56 | tripartite motif containing 56 | -0.0153645 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0151232 |
| GPATCH2L | G patch domain containing 2-like | -0.0151185 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa | -0.0150448 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0149778 |
| MYO9A | myosin IXA | -0.0149776 |
| TBL1X | transducin (beta)-like 1X-linked | -0.014939 |
| TAOK1 | TAO kinase 1 | -0.0146804 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.0146662 |
