| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bendamustine perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bendamustine_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | 0.0898878 |
| PCBP2 | poly(rC) binding protein 2 | 0.0865821 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0810847 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0772003 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0730739 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0715451 |
| CDH13 | cadherin 13 | 0.0555508 |
| FN1 | fibronectin 1 | 0.054986 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.053553 |
| ATP13A3 | ATPase type 13A3 | 0.0484579 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0467868 |
| MEF2A | myocyte enhancer factor 2A | 0.0462436 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0453477 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0430805 |
| FAM20C | family with sequence similarity 20, member C | 0.0419407 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0398961 |
| PTK2 | protein tyrosine kinase 2 | 0.0393262 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0392496 |
| PGK1 | phosphoglycerate kinase 1 | 0.0383903 |
| QKI | QKI, KH domain containing, RNA binding | 0.0356416 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0354035 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0344803 |
| RNF145 | ring finger protein 145 | 0.0344009 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0343378 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0342039 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0330527 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0330463 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0319326 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0314467 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0314459 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.031382 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0313156 |
| PKM | pyruvate kinase, muscle | 0.0312913 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0312781 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.03106 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0310445 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0310314 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0303226 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0297716 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0296542 |
| XPO1 | exportin 1 | 0.0293804 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0292835 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0287264 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0286364 |
| CCNY | cyclin Y | 0.0285522 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0284025 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0282368 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0281358 |
| NUP58 | nucleoporin 58 | 0.0279921 |
| ENO1 | enolase 1, (alpha) | 0.0279863 |
| RPL3 | ribosomal protein L3 | 0.0278501 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.027357 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0272607 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0269584 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0267294 |
| ADM | adrenomedullin | 0.0263579 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.026343 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0262506 |
| RAB21 | RAB21, member RAS oncogene family | 0.0261431 |
| MATR3 | matrin 3 | 0.0255733 |
| ANO6 | anoctamin 6 | 0.0254479 |
| FAM13A | family with sequence similarity 13, member A | 0.0251821 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | 0.0251259 |
| CTNNBL1 | catenin, beta like 1 | 0.0248838 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0248026 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0247548 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0247394 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0244695 |
| HELZ | helicase with zinc finger | 0.024393 |
| DST | dystonin | 0.024327 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0243019 |
| INSIG2 | insulin induced gene 2 | 0.024171 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0239607 |
| MYO1B | myosin IB | 0.0238151 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.023408 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0232371 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0229961 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0228885 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0227504 |
| CA12 | carbonic anhydrase XII | 0.0227393 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0226194 |
| FBN1 | fibrillin 1 | 0.0225348 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.0224014 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0223667 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0223594 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0222032 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.022164 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0218686 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0218394 |
| RIOK3 | RIO kinase 3 | 0.0215949 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0215839 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0214827 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0214779 |
| MSN | moesin | 0.0214212 |
| FMNL2 | formin-like 2 | 0.0214032 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0213824 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0213554 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.021088 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0210819 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0209976 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.224834 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.147212 |
| CD44 | CD44 molecule (Indian blood group) | -0.137263 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.126945 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.122549 |
| TMSB10 | thymosin beta 10 | -0.100211 |
| OSMR | oncostatin M receptor | -0.091256 |
| EFNA5 | ephrin-A5 | -0.0772019 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0677107 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0664623 |
| GLCCI1 | glucocorticoid induced 1 | -0.0661976 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.063666 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0610158 |
| RBM39 | RNA binding motif protein 39 | -0.0575912 |
| MT2A | metallothionein 2A | -0.056598 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0554631 |
| CANX | calnexin | -0.0530382 |
| KLF6 | Kruppel-like factor 6 | -0.0506534 |
| H1-0 | H1.0 linker histone | -0.0502133 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0483872 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0478173 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0467526 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0460267 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0449633 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0444967 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0444271 |
| USP34 | ubiquitin specific peptidase 34 | -0.0441506 |
| BPTF | bromodomain PHD finger transcription factor | -0.0434958 |
| TMEM263 | transmembrane protein 263 | -0.0433751 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0426935 |
| NTN4 | netrin 4 | -0.0425398 |
| GOLGA4 | golgin A4 | -0.041657 |
| RPS19 | ribosomal protein S19 | -0.0414195 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0412216 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0411991 |
| SBF2 | SET binding factor 2 | -0.0395783 |
| RPLP1 | ribosomal protein, large, P1 | -0.0391689 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0386189 |
| IER3 | immediate early response 3 | -0.0382432 |
| FTL | ferritin, light polypeptide | -0.0375169 |
| AHNAK | AHNAK nucleoprotein | -0.0369876 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0365133 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0364614 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0363869 |
| NRP1 | neuropilin 1 | -0.0363254 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0353451 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0351676 |
| EGR1 | early growth response 1 | -0.0350803 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0340562 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0337691 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0337146 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0334849 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0334644 |
| KYNU | kynureninase | -0.0333648 |
| RAD51B | RAD51 paralog B | -0.0332139 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0323381 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0320288 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0319586 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0312828 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0310466 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.030296 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.0302608 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0302216 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0296847 |
| MYO9A | myosin IXA | -0.0294779 |
| SYAP1 | synapse associated protein 1 | -0.0293946 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0292751 |
| RPL35A | ribosomal protein L35a | -0.0291386 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0291191 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0289743 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0283648 |
| PRELID2 | PRELI domain containing 2 | -0.0283229 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0281845 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.027816 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0273568 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0269782 |
| RPL32 | ribosomal protein L32 | -0.0267662 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0266533 |
| MORF4L2 | mortality factor 4 like 2 | -0.0264637 |
| OGA | O-GlcNAcase | -0.0257549 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0257151 |
| ZFP91 | ZFP91 zinc finger protein | -0.0254397 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0251941 |
| CCDC88A | coiled-coil domain containing 88A | -0.0251173 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0250849 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.025064 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0250387 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0249518 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0249505 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0249135 |
| MYO1E | myosin IE | -0.0248661 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0248611 |
| AOPEP | aminopeptidase O (putative) | -0.024796 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0247691 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.024391 |
| RPS24 | ribosomal protein S24 | -0.0243572 |
| RPL23 | ribosomal protein L23 | -0.0243404 |
| NDRG1 | N-myc downstream regulated 1 | -0.0242446 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0242 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0240019 |
