| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bendamustine perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bendamustine_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | 0.158935 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.146974 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.105882 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0751902 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0609067 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0592097 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0536564 |
| PCBP2 | poly(rC) binding protein 2 | 0.042618 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.042074 |
| STC1 | stanniocalcin 1 | 0.0379575 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0354941 |
| ENO1 | enolase 1, (alpha) | 0.0327674 |
| MSN | moesin | 0.0326614 |
| TPM3 | tropomyosin 3 | 0.0319116 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0297691 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0287311 |
| RRM2 | ribonucleotide reductase M2 | 0.0284578 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0268475 |
| TPM4 | tropomyosin 4 | 0.0265961 |
| FLNB | filamin B, beta | 0.0265956 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0258348 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.025804 |
| RPL3 | ribosomal protein L3 | 0.0254883 |
| HDGF | hepatoma-derived growth factor | 0.0250421 |
| MYOF | myoferlin | 0.0243128 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0237527 |
| MUSK | muscle, skeletal, receptor tyrosine kinase | 0.0233087 |
| FGB | fibrinogen beta chain | 0.0227965 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0225243 |
| EZR | ezrin | 0.0221985 |
| CENPF | centromere protein F, 350/400kDa | 0.0220917 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0219059 |
| LDHB | lactate dehydrogenase B | 0.0214019 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0211551 |
| NDRG1 | N-myc downstream regulated 1 | 0.0209603 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0207879 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.020649 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0204733 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0204388 |
| EGFR | epidermal growth factor receptor | 0.0200244 |
| CMIP | c-Maf inducing protein | 0.019636 |
| ITGA6 | integrin, alpha 6 | 0.0195242 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0192813 |
| SEPTIN9 | septin 9 | 0.0192486 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0191889 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0190089 |
| SERINC3 | serine incorporator 3 | 0.0189395 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0189345 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0185116 |
| MCL1 | myeloid cell leukemia 1 | 0.0183411 |
| CBX3 | chromobox homolog 3 | 0.0179037 |
| PAIP1 | poly(A) binding protein interacting protein 1 | 0.0178418 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0174308 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0173862 |
| COPA | coatomer protein complex, subunit alpha | 0.0171456 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.017141 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0170625 |
| CTSL | cathepsin L | 0.0167292 |
| ANGPTL4 | angiopoietin-like 4 | 0.0166482 |
| MATR3 | matrin 3 | 0.0161119 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0159952 |
| THBS1 | thrombospondin 1 | 0.0159215 |
| CUX1 | cut-like homeobox 1 | 0.0159134 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0155857 |
| RPS18 | ribosomal protein S18 | 0.0155752 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.015209 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.015151 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0151082 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0150476 |
| MLEC | malectin | 0.0149748 |
| ASTN2 | astrotactin 2 | 0.0149715 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0149414 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0148871 |
| KIF5B | kinesin family member 5B | 0.0148819 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0146333 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0145302 |
| RCOR1 | REST corepressor 1 | 0.0145162 |
| IDS | iduronate 2-sulfatase | 0.0143603 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0142944 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0142635 |
| PYGL | phosphorylase, glycogen, liver | 0.0142441 |
| LDHA | lactate dehydrogenase A | 0.0140676 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.0140675 |
| UBC | ubiquitin C | 0.0140526 |
| SET | SET nuclear proto-oncogene | 0.0140265 |
| VIM | vimentin | 0.0139824 |
| ZNF609 | zinc finger protein 609 | 0.0137702 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0137371 |
| LAMC2 | laminin, gamma 2 | 0.0137158 |
| NUMB | numb homolog (Drosophila) | 0.0136993 |
| EHBP1 | EH domain binding protein 1 | 0.0136148 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0135968 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0135481 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0135232 |
| AATF | apoptosis antagonizing transcription factor | 0.013492 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | 0.0134624 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0134577 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0134492 |
| UBE2V2 | ubiquitin-conjugating enzyme E2 variant 2 | 0.0134059 |
| CDCP1 | CUB domain containing protein 1 | 0.0133168 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.322033 |
| TMSB10 | thymosin beta 10 | -0.17338 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.140683 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.129541 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0874146 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0861986 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.083791 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0762604 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0715772 |
| IER3 | immediate early response 3 | -0.0693815 |
| GRAMD1B | GRAM domain containing 1B | -0.0603118 |
| RBM39 | RNA binding motif protein 39 | -0.0601553 |
| FTL | ferritin, light polypeptide | -0.0590931 |
| ZNF292 | zinc finger protein 292 | -0.055156 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.054455 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.053891 |
| TXNRD1 | thioredoxin reductase 1 | -0.0538397 |
| RPL26 | ribosomal protein L26 | -0.05334 |
| RPL19 | ribosomal protein L19 | -0.0524031 |
| WDR43 | WD repeat domain 43 | -0.0510148 |
| RPS21 | ribosomal protein S21 | -0.0502208 |
| RPL4 | ribosomal protein L4 | -0.0483585 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.048093 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0471623 |
| APP | amyloid beta (A4) precursor protein | -0.0464949 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0462143 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0461366 |
| RPL23 | ribosomal protein L23 | -0.0460955 |
| PARD3 | par-3 family cell polarity regulator | -0.0460769 |
| DENND4A | DENN/MADD domain containing 4A | -0.0433796 |
| RPS8 | ribosomal protein S8 | -0.0430658 |
| OLA1 | Obg-like ATPase 1 | -0.0430261 |
| USP3 | ubiquitin specific peptidase 3 | -0.0428859 |
| RPL30 | ribosomal protein L30 | -0.0427483 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0419933 |
| RPLP1 | ribosomal protein, large, P1 | -0.0416031 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0411193 |
| FUS | FUS RNA binding protein | -0.0410962 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0397105 |
| WTAP | Wilms tumor 1 associated protein | -0.0388403 |
| RPS19 | ribosomal protein S19 | -0.0383826 |
| RPL7 | ribosomal protein L7 | -0.0382202 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0382155 |
| FBXO11 | F-box protein 11 | -0.0379761 |
| IGF2 | insulin-like growth factor 2 | -0.0375349 |
| PTK2 | protein tyrosine kinase 2 | -0.0373068 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0371789 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0368052 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0367544 |
| BTBD7 | BTB (POZ) domain containing 7 | -0.0367445 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -0.0366955 |
| ABI1 | abl-interactor 1 | -0.0366488 |
| BICC1 | BicC family RNA binding protein 1 | -0.0365403 |
| RPL36 | ribosomal protein L36 | -0.0362882 |
| NOP58 | NOP58 ribonucleoprotein | -0.035906 |
| SLC38A1 | solute carrier family 38, member 1 | -0.035738 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0351995 |
| WWOX | WW domain containing oxidoreductase | -0.0347266 |
| YBX3 | Y box binding protein 3 | -0.0344624 |
| CAVIN1 | caveolae associated protein 1 | -0.034409 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0339976 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0331655 |
| RPS12 | ribosomal protein S12 | -0.0330003 |
| KLF6 | Kruppel-like factor 6 | -0.0328622 |
| QKI | QKI, KH domain containing, RNA binding | -0.0328162 |
| RPL13A | ribosomal protein L13a | -0.0326496 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0322353 |
| RPL5 | ribosomal protein L5 | -0.0321272 |
| RASAL2 | RAS protein activator like 2 | -0.0319566 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0319445 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0318632 |
| RPS5 | ribosomal protein S5 | -0.0318506 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0318231 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0317855 |
| RPS27A | ribosomal protein S27a | -0.0317413 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0317003 |
| RPS24 | ribosomal protein S24 | -0.0308719 |
| RPL35A | ribosomal protein L35a | -0.0307696 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0305072 |
| ANXA2 | annexin A2 | -0.0303091 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0301471 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0300675 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0300262 |
| SERF2 | small EDRK-rich factor 2 | -0.0296934 |
| RPS29 | ribosomal protein S29 | -0.0293631 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.029139 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0287917 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0285901 |
| RPL34 | ribosomal protein L34 | -0.0282503 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0280951 |
| RPL37A | ribosomal protein L37a | -0.028064 |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | -0.0279842 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0279404 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0276787 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0275737 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0275619 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0275596 |
| RPL36AL | ribosomal protein L36a-like | -0.0272707 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0270728 |
| SRSF7 | serine/arginine-rich splicing factor 7 | -0.0269341 |
