| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bendamustine perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bendamustine_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.130841 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.117971 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.103962 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0983401 |
| FAM13A | family with sequence similarity 13, member A | 0.0917103 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0900881 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0882162 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0835112 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0825932 |
| KRT17 | keratin 17, type I | 0.0798808 |
| USP3 | ubiquitin specific peptidase 3 | 0.0788141 |
| NPTN | neuroplastin | 0.0728467 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0725295 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0717196 |
| PCBP2 | poly(rC) binding protein 2 | 0.0689027 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0681069 |
| RBM39 | RNA binding motif protein 39 | 0.067505 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0661429 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0650068 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0650055 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0643136 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0629316 |
| DENND4C | DENN/MADD domain containing 4C | 0.0622217 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0620986 |
| PLAU | plasminogen activator, urokinase | 0.0610073 |
| RNF145 | ring finger protein 145 | 0.0604984 |
| ADM | adrenomedullin | 0.0596147 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0593584 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0587314 |
| STC1 | stanniocalcin 1 | 0.0578709 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0577365 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0574154 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0570236 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0563391 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.05629 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0557862 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0548335 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.0545958 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0537279 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0536569 |
| FNBP1L | formin binding protein 1-like | 0.0526447 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0507407 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0505418 |
| PGK1 | phosphoglycerate kinase 1 | 0.0501748 |
| ZNF292 | zinc finger protein 292 | 0.0499242 |
| CCNY | cyclin Y | 0.04969 |
| REPS1 | RALBP1 associated Eps domain containing 1 | 0.0491407 |
| IRS2 | insulin receptor substrate 2 | 0.0488159 |
| ENO1 | enolase 1, (alpha) | 0.0485036 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0484131 |
| DTNA | dystrobrevin, alpha | 0.0478979 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0472793 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.046267 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0461729 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0460781 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0460045 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0456329 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0444724 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0440394 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0436928 |
| TOP1 | topoisomerase (DNA) I | 0.0435899 |
| TUFT1 | tuftelin 1 | 0.0430475 |
| OGA | O-GlcNAcase | 0.0427349 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0423556 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.042316 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0418358 |
| RYBP | RING1 and YY1 binding protein | 0.0416514 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0415675 |
| SAR1A | secretion associated, Ras related GTPase 1A | 0.0415458 |
| MYO10 | myosin X | 0.0411291 |
| ATP13A3 | ATPase type 13A3 | 0.040849 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.040563 |
| SLK | STE20-like kinase | 0.0403329 |
| PTMA | prothymosin, alpha | 0.0402205 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0400467 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0391591 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0390091 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0389004 |
| CDC73 | cell division cycle 73 | 0.0385748 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0382724 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0381854 |
| ATG14 | autophagy related 14 | 0.0376863 |
| TPM3 | tropomyosin 3 | 0.0369912 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0367866 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0367687 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0364621 |
| SYT1 | synaptotagmin I | 0.0364487 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0363785 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0362808 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0361067 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.03565 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0355403 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0354393 |
| SETX | senataxin | 0.0353524 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0350038 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0346377 |
| HLA-A | major histocompatibility complex, class I, A | 0.0344792 |
| PHF3 | PHD finger protein 3 | 0.0341397 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0340961 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0340322 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.198823 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.176216 |
| MYO1E | myosin IE | -0.152425 |
| LMO7 | LIM domain 7 | -0.143139 |
| IGF2 | insulin-like growth factor 2 | -0.13334 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.121787 |
| MT2A | metallothionein 2A | -0.120993 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.116349 |
| FTL | ferritin, light polypeptide | -0.111147 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.110703 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.096305 |
| SVIL | supervillin | -0.0837349 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.082106 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0764277 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0731075 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0728763 |
| EFNA5 | ephrin-A5 | -0.0724829 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0720626 |
| SMYD3 | SET and MYND domain containing 3 | -0.0696384 |
| ASPH | aspartate beta-hydroxylase | -0.0695882 |
| FBXO11 | F-box protein 11 | -0.0687777 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0652588 |
| CMIP | c-Maf inducing protein | -0.0635346 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0629338 |
| RPS16 | ribosomal protein S16 | -0.0623647 |
| ANXA2 | annexin A2 | -0.0622814 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0619594 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0617583 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0591011 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0586424 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0549184 |
| AHNAK | AHNAK nucleoprotein | -0.0544833 |
| VIM | vimentin | -0.0544721 |
| TXNRD1 | thioredoxin reductase 1 | -0.0535315 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0526045 |
| RBM47 | RNA binding motif protein 47 | -0.0521831 |
| RNF213 | ring finger protein 213 | -0.0512863 |
| LAMC2 | laminin, gamma 2 | -0.051026 |
| RAD51B | RAD51 paralog B | -0.0510259 |
| GLIS3 | GLIS family zinc finger 3 | -0.0496957 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0492287 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0488611 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0478446 |
| GPC6 | glypican 6 | -0.0474613 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.046823 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0460266 |
| LAMB3 | laminin, beta 3 | -0.0459371 |
| FN1 | fibronectin 1 | -0.0455966 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0455247 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0444995 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0431772 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0425389 |
| LOXL2 | lysyl oxidase-like 2 | -0.0420507 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0409835 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0408465 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0407481 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0404643 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0400225 |
| POTEF | POTE ankyrin domain family, member F | -0.039889 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0392812 |
| OSMR | oncostatin M receptor | -0.0388524 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0387373 |
| NF1 | neurofibromin 1 | -0.038491 |
| KYNU | kynureninase | -0.0379609 |
| VCL | vinculin | -0.0375305 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0360802 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0359748 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.035224 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0347945 |
| ATOSA | atos homolog A | -0.0346667 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0342113 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0336019 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0333715 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0332752 |
| CD44 | CD44 molecule (Indian blood group) | -0.0329132 |
| MYOF | myoferlin | -0.0328429 |
| ZNF638 | zinc finger protein 638 | -0.032813 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0325406 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0321887 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0317964 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0313849 |
| BBX | bobby sox homolog (Drosophila) | -0.0313754 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0313665 |
| S100A10 | S100 calcium binding protein A10 | -0.0313321 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0311567 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0311029 |
| FLNB | filamin B, beta | -0.0309517 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.030772 |
| JMJD1C | jumonji domain containing 1C | -0.0299194 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0298465 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0298077 |
| AK1 | adenylate kinase 1 | -0.0297761 |
| ACTG1 | actin gamma 1 | -0.029559 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0295227 |
| RPS6 | ribosomal protein S6 | -0.0294023 |
| CUX1 | cut-like homeobox 1 | -0.0289051 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0288371 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0285733 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0284741 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0275165 |
