| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bendamustine perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bendamustine_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.201168 |
| POTEF | POTE ankyrin domain family, member F | 0.185888 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.1046 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0912659 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0674696 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0622011 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0565092 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0563533 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.05229 |
| KRT7 | keratin 7, type II | 0.0509627 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0496544 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0481829 |
| MSN | moesin | 0.0480371 |
| TPM3 | tropomyosin 3 | 0.0451968 |
| TXNRD1 | thioredoxin reductase 1 | 0.043487 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0422319 |
| ASPH | aspartate beta-hydroxylase | 0.040752 |
| LAMC2 | laminin, gamma 2 | 0.0402309 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0390155 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0366733 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.035306 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0312304 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0311436 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0311025 |
| PLAU | plasminogen activator, urokinase | 0.0303533 |
| NCKAP1 | NCK-associated protein 1 | 0.0289143 |
| DSPP | dentin sialophosphoprotein | 0.0287957 |
| CTSB | cathepsin B | 0.0281884 |
| RPL3 | ribosomal protein L3 | 0.028064 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0269572 |
| CENPF | centromere protein F, 350/400kDa | 0.0262272 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0256722 |
| ARF6 | ADP-ribosylation factor 6 | 0.0254204 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0251853 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0251409 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0249752 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0248945 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0247777 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0246937 |
| CD47 | CD47 molecule | 0.0246769 |
| DST | dystonin | 0.0245391 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0242137 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0239818 |
| PEG10 | paternally expressed 10 | 0.0235512 |
| UBC | ubiquitin C | 0.0231734 |
| PCBP2 | poly(rC) binding protein 2 | 0.0227533 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0226367 |
| SET | SET nuclear proto-oncogene | 0.0220911 |
| ARRDC3 | arrestin domain containing 3 | 0.0220701 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0219684 |
| DEK | DEK proto-oncogene | 0.0219168 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0213854 |
| RPLP0 | ribosomal protein, large, P0 | 0.0210677 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0208688 |
| CPNE8 | copine VIII | 0.0208512 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0200748 |
| MATR3 | matrin 3 | 0.0198265 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0195722 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0194912 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0192361 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0191501 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0191015 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0190167 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0190055 |
| ITGAV | integrin, alpha V | 0.0189438 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0189176 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0187713 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.01844 |
| MKI67 | marker of proliferation Ki-67 | 0.0184238 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0183193 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0182394 |
| PAPOLA | poly(A) polymerase alpha | 0.0181127 |
| KRT18 | keratin 18, type I | 0.0180453 |
| CALR | calreticulin | 0.0178836 |
| CD83 | CD83 molecule | 0.0178618 |
| NONO | non-POU domain containing, octamer-binding | 0.0176923 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0174603 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0174418 |
| HDGF | hepatoma-derived growth factor | 0.0173308 |
| ANLN | anillin, actin binding protein | 0.0168234 |
| CCND1 | cyclin D1 | 0.0167806 |
| TUBA1B | tubulin, alpha 1b | 0.0167359 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0165027 |
| RPS18 | ribosomal protein S18 | 0.0164571 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0164478 |
| TES | testin LIM domain protein | 0.0164183 |
| IPO7 | importin 7 | 0.0164061 |
| UPP1 | uridine phosphorylase 1 | 0.0163968 |
| SERINC1 | serine incorporator 1 | 0.0163967 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0162551 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0162226 |
| SCEL | sciellin | 0.0160497 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.0157494 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0157179 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0156897 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0156437 |
| KRT8 | keratin 8, type II | 0.0155626 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0154226 |
| STEAP4 | STEAP family member 4 | 0.0152171 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0151004 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.288411 |
| TMSB10 | thymosin beta 10 | -0.218469 |
| PTMA | prothymosin, alpha | -0.165902 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.138273 |
| ACTG1 | actin gamma 1 | -0.103436 |
| MT2A | metallothionein 2A | -0.098697 |
| NDRG1 | N-myc downstream regulated 1 | -0.085366 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0801179 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0799626 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0687564 |
| LAMB3 | laminin, beta 3 | -0.0678158 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0677627 |
| RPL35A | ribosomal protein L35a | -0.0650172 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0597905 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0596961 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.059541 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0583085 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0576053 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0566972 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0565201 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0556941 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.054957 |
| RPL37A | ribosomal protein L37a | -0.0547195 |
| RPS19 | ribosomal protein S19 | -0.0544553 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0542456 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0534068 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0515488 |
| CSTB | cystatin B (stefin B) | -0.0513657 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0511304 |
| RPLP2 | ribosomal protein, large, P2 | -0.0509449 |
| GNAS | GNAS complex locus | -0.0497964 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0497936 |
| HLA-A | major histocompatibility complex, class I, A | -0.049456 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0491539 |
| RPLP1 | ribosomal protein, large, P1 | -0.0491443 |
| RPS29 | ribosomal protein S29 | -0.0481764 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0474324 |
| RPS3 | ribosomal protein S3 | -0.0455607 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0450487 |
| FLNB | filamin B, beta | -0.0445787 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0435198 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0434198 |
| RPS8 | ribosomal protein S8 | -0.0433968 |
| S100A6 | S100 calcium binding protein A6 | -0.043385 |
| S100A9 | S100 calcium binding protein A9 | -0.0433468 |
| MYO1E | myosin IE | -0.0425211 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.042212 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0413352 |
| FBXO32 | F-box protein 32 | -0.0412424 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0406268 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0402426 |
| GOLGA4 | golgin A4 | -0.0400261 |
| LMNA | lamin A/C | -0.0395234 |
| RPL30 | ribosomal protein L30 | -0.0380886 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0379821 |
| EGR1 | early growth response 1 | -0.0378523 |
| RPL34 | ribosomal protein L34 | -0.0377517 |
| FBXO11 | F-box protein 11 | -0.036918 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0367607 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0365736 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0362296 |
| RPS27 | ribosomal protein S27 | -0.0362253 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0361387 |
| RBM25 | RNA binding motif protein 25 | -0.0360699 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0360438 |
| HLA-B | major histocompatibility complex, class I, B | -0.0351741 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0350266 |
| SPAG9 | sperm associated antigen 9 | -0.0348651 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0340371 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0336293 |
| RRBP1 | ribosome binding protein 1 | -0.0332137 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0329897 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0329591 |
| ZNF292 | zinc finger protein 292 | -0.0329107 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.032812 |
| USP53 | ubiquitin specific peptidase 53 | -0.0325903 |
| WASF2 | WAS protein family, member 2 | -0.0318178 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.031489 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0314646 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.031459 |
| RPL19 | ribosomal protein L19 | -0.0313866 |
| MCU | mitochondrial calcium uniporter | -0.0313764 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0312643 |
| DTNA | dystrobrevin, alpha | -0.0311932 |
| RNF213 | ring finger protein 213 | -0.0310493 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0309438 |
| TMEM165 | transmembrane protein 165 | -0.0303993 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0303832 |
| GOLGB1 | golgin B1 | -0.0302858 |
| G0S2 | G0/G1 switch 2 | -0.0301962 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0300356 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0300127 |
| EFNA5 | ephrin-A5 | -0.0298787 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.029739 |
| MCL1 | myeloid cell leukemia 1 | -0.0297236 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0295471 |
| CERT1 | ceramide transporter 1 | -0.0293705 |
| RLF | rearranged L-myc fusion | -0.0289362 |
| RCOR1 | REST corepressor 1 | -0.0287291 |
| RPL27A | ribosomal protein L27a | -0.0286934 |
