| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bendamustine perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bendamustine_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.173556 |
| ASPH | aspartate beta-hydroxylase | 0.142885 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0979424 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0890445 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0882861 |
| POTEF | POTE ankyrin domain family, member F | 0.0868206 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0829439 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0717657 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0669254 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0662979 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0639223 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0616379 |
| ENO1 | enolase 1, (alpha) | 0.0572616 |
| EFNA5 | ephrin-A5 | 0.0571178 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0570597 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0554892 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0535294 |
| CENPF | centromere protein F, 350/400kDa | 0.0528297 |
| GRAMD1B | GRAM domain containing 1B | 0.052364 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0489825 |
| NEK7 | NIMA-related kinase 7 | 0.0474977 |
| KYNU | kynureninase | 0.0463737 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0442449 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0432366 |
| RPL23 | ribosomal protein L23 | 0.0421447 |
| MYOF | myoferlin | 0.0414936 |
| RPS12 | ribosomal protein S12 | 0.0404545 |
| CTSC | cathepsin C | 0.0399935 |
| RPL12 | ribosomal protein L12 | 0.0393303 |
| PDE10A | phosphodiesterase 10A | 0.0388829 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0387266 |
| RPL3 | ribosomal protein L3 | 0.0387198 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0369194 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0367617 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0353062 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0343036 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0334969 |
| PGK1 | phosphoglycerate kinase 1 | 0.0332195 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0331835 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0323028 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0322349 |
| SET | SET nuclear proto-oncogene | 0.0319713 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0317906 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0315206 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0314274 |
| PRDX1 | peroxiredoxin 1 | 0.0309724 |
| PCBP3 | poly(rC) binding protein 3 | 0.0307232 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0305789 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0301069 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0292553 |
| PDE7B | phosphodiesterase 7B | 0.0292409 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0289084 |
| TPM3 | tropomyosin 3 | 0.0281341 |
| COL5A2 | collagen, type V, alpha 2 | 0.0280437 |
| KIAA0825 | KIAA0825 | 0.0269869 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0267345 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0261644 |
| TXNRD1 | thioredoxin reductase 1 | 0.0251767 |
| NRCAM | neuronal cell adhesion molecule | 0.0249049 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0248713 |
| LDHA | lactate dehydrogenase A | 0.023858 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.0237866 |
| CDK6 | cyclin-dependent kinase 6 | 0.0236867 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0236128 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0235428 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0231378 |
| KIF5B | kinesin family member 5B | 0.0227451 |
| MKI67 | marker of proliferation Ki-67 | 0.0226813 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.022637 |
| RPL26 | ribosomal protein L26 | 0.0225091 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0223886 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0223059 |
| APP | amyloid beta (A4) precursor protein | 0.0220981 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0220909 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0219275 |
| RTN1 | reticulon 1 | 0.0218755 |
| RPS7 | ribosomal protein S7 | 0.0218731 |
| BDNF | brain-derived neurotrophic factor | 0.0213676 |
| PTMA | prothymosin, alpha | 0.0210986 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0205412 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0204324 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0204127 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0203985 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0203363 |
| TKT | transketolase | 0.0199187 |
| RPL4 | ribosomal protein L4 | 0.0197033 |
| RACK1 | receptor for activated C kinase 1 | 0.0195742 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0194175 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0193924 |
| TPR | translocated promoter region, nuclear basket protein | 0.0193722 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.0193274 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0192634 |
| RPL11 | ribosomal protein L11 | 0.0191883 |
| RGS2 | regulator of G-protein signaling 2 | 0.0189758 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.018938 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0186238 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0185712 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0184733 |
| CDH13 | cadherin 13 | 0.0183328 |
| NONO | non-POU domain containing, octamer-binding | 0.0180986 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.234664 |
| FN1 | fibronectin 1 | -0.212519 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.199557 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.195599 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0986059 |
| NDRG1 | N-myc downstream regulated 1 | -0.0842402 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0756768 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0715558 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0702263 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0669632 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0646833 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0618282 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0612388 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0536566 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0519303 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0510038 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0508457 |
| NBEAL1 | neurobeachin-like 1 | -0.0490436 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0479517 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0457663 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0452718 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0451552 |
| COPA | coatomer protein complex, subunit alpha | -0.0434033 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0433358 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0412757 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0405786 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0398839 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0397751 |
| EGR1 | early growth response 1 | -0.0391471 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0391193 |
| SPAG9 | sperm associated antigen 9 | -0.0381803 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0377811 |
| MCL1 | myeloid cell leukemia 1 | -0.0362167 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0361918 |
| HLA-A | major histocompatibility complex, class I, A | -0.035807 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0353426 |
| UBC | ubiquitin C | -0.0353264 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0352331 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0352057 |
| GOLGA4 | golgin A4 | -0.0347835 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0346402 |
| FMNL2 | formin-like 2 | -0.0345425 |
| WDR45B | WD repeat domain 45B | -0.0342478 |
| JMJD1C | jumonji domain containing 1C | -0.0339119 |
| GNAS | GNAS complex locus | -0.0336988 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0335897 |
| RTN4 | reticulon 4 | -0.033375 |
| LAMA5 | laminin, alpha 5 | -0.0331044 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0329343 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0328129 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0320915 |
| TMEM165 | transmembrane protein 165 | -0.0313352 |
| ABLIM1 | actin binding LIM protein 1 | -0.0307211 |
| CREB5 | cAMP responsive element binding protein 5 | -0.030686 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0304484 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0304072 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0303571 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0298197 |
| HLA-B | major histocompatibility complex, class I, B | -0.0297513 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0297409 |
| CCDC88A | coiled-coil domain containing 88A | -0.029695 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0295375 |
| SBF2 | SET binding factor 2 | -0.0295268 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0295222 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0293733 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0288846 |
| VIM | vimentin | -0.0287137 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0286446 |
| CD44 | CD44 molecule (Indian blood group) | -0.0285483 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.028389 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0280456 |
| IL6 | interleukin 6 | -0.0280201 |
| BMERB1 | bMERB domain containing 1 | -0.0276468 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0275347 |
| FAM13A | family with sequence similarity 13, member A | -0.0273396 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0270586 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0270436 |
| MAP7 | microtubule-associated protein 7 | -0.0268048 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0266108 |
| ZNF638 | zinc finger protein 638 | -0.0264576 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0264095 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0260821 |
| CANX | calnexin | -0.0259647 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0258983 |
| FNIP1 | folliculin interacting protein 1 | -0.0258003 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0254784 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0252 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0251576 |
| USP34 | ubiquitin specific peptidase 34 | -0.0251099 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0250871 |
| FTL | ferritin, light polypeptide | -0.0249456 |
| SEC24A | SEC24 family member A | -0.0248141 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0244749 |
| CUX1 | cut-like homeobox 1 | -0.0243533 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0242501 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.023882 |
| FBXO11 | F-box protein 11 | -0.0238709 |
| MAP1B | microtubule-associated protein 1B | -0.0235631 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0234948 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0234883 |
