| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bendamustine perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bendamustine_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0944908 |
| PEG10 | paternally expressed 10 | 0.0530978 |
| COL3A1 | collagen, type III, alpha 1 | 0.0438871 |
| POTEF | POTE ankyrin domain family, member F | 0.04337 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0370186 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0353876 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0337869 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0334292 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0301485 |
| GRB2 | growth factor receptor-bound protein 2 | 0.0286517 |
| FN1 | fibronectin 1 | 0.0280261 |
| HMGB2 | high mobility group box 2 | 0.0278479 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0266036 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0253763 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0251206 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0247927 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0244483 |
| PDE8A | phosphodiesterase 8A | 0.0243754 |
| ASPH | aspartate beta-hydroxylase | 0.0242469 |
| RPL3 | ribosomal protein L3 | 0.0241851 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0239607 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0238923 |
| SETD2 | SET domain containing 2 | 0.0238399 |
| COL1A2 | collagen, type I, alpha 2 | 0.0236596 |
| MED12L | mediator complex subunit 12-like | 0.0225817 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0217065 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha | 0.0215176 |
| CHD8 | chromodomain helicase DNA binding protein 8 | 0.0210756 |
| BRD2 | bromodomain containing 2 | 0.0209296 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0209142 |
| IPO7 | importin 7 | 0.0207451 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | 0.0205909 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.020138 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | 0.0200399 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.020035 |
| CORO1C | coronin, actin binding protein, 1C | 0.0199306 |
| RHOA | ras homolog family member A | 0.0197607 |
| MORF4L1 | mortality factor 4 like 1 | 0.0196883 |
| MKI67 | marker of proliferation Ki-67 | 0.0193512 |
| KATNBL1 | katanin p80 subunit B-like 1 | 0.019296 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0192261 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0190441 |
| SEC24D | SEC24 family member D | 0.0189384 |
| RINT1 | RAD50 interactor 1 | 0.0188852 |
| PCDH18 | protocadherin 18 | 0.0187884 |
| LBR | lamin B receptor | 0.0186291 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0183871 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0183635 |
| PM20D1 | peptidase M20 domain containing 1 | 0.018361 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | 0.0182327 |
| UBE4A | ubiquitination factor E4A | 0.0180267 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0180164 |
| CCNB1 | cyclin B1 | 0.0179655 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0179135 |
| PCNT | pericentrin | 0.0179126 |
| FZD9 | frizzled class receptor 9 | 0.0179072 |
| CCNA2 | cyclin A2 | 0.0178665 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0177109 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0177096 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0175683 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0173963 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0173798 |
| FOXP2 | forkhead box P2 | 0.0171984 |
| TUSC3 | tumor suppressor candidate 3 | 0.0171977 |
| CCNY | cyclin Y | 0.0171859 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.0171818 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.017013 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0169827 |
| WBP11 | WW domain binding protein 11 | 0.0169611 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0168363 |
| EXOC5 | exocyst complex component 5 | 0.0167969 |
| FAM171B | family with sequence similarity 171, member B | 0.0166945 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0166519 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0165395 |
| SNX27 | sorting nexin family member 27 | 0.0164945 |
| M6PR | mannose-6-phosphate receptor (cation dependent) | 0.0164169 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.0163518 |
| ZNF451 | zinc finger protein 451 | 0.0162452 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0161956 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0161949 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0161715 |
| NUCB2 | nucleobindin 2 | 0.0161252 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.0159906 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 0.0158448 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0158356 |
| GPR158 | G protein-coupled receptor 158 | 0.0156669 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0156636 |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 0.0156241 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0156049 |
| TERF1 | telomeric repeat binding factor (NIMA-interacting) 1 | 0.0155562 |
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 0.0155493 |
| CALU | calumenin | 0.0155238 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.0154822 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0154808 |
| ZBTB37 | zinc finger and BTB domain containing 37 | 0.0154758 |
| RBBP8 | retinoblastoma binding protein 8 | 0.015467 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0154332 |
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) | 0.0153784 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | 0.0153673 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0153408 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.190237 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.164674 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.163686 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.11375 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.110212 |
| PTMA | prothymosin, alpha | -0.0860078 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0821388 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0801623 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0755483 |
| RPS16 | ribosomal protein S16 | -0.0727762 |
| HMGB1 | high mobility group box 1 | -0.0725094 |
| RPLP1 | ribosomal protein, large, P1 | -0.0722175 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0710766 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0699692 |
| SPAG9 | sperm associated antigen 9 | -0.069286 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0688174 |
| PHIP | pleckstrin homology domain interacting protein | -0.0679159 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0650746 |
| VIM | vimentin | -0.0632334 |
| RPS12 | ribosomal protein S12 | -0.0617257 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0612487 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0610395 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0608892 |
| CADM2 | cell adhesion molecule 2 | -0.0606471 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.059775 |
| PLPP1 | phospholipid phosphatase 1 | -0.0593105 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0591137 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0582728 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0576922 |
| YBX1 | Y box binding protein 1 | -0.0560384 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0547574 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0540558 |
| COL5A2 | collagen, type V, alpha 2 | -0.0538877 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0516685 |
| RPLP2 | ribosomal protein, large, P2 | -0.0514561 |
| NEBL | nebulette | -0.05057 |
| ACTG1 | actin gamma 1 | -0.0487214 |
| SRP54 | signal recognition particle 54kDa | -0.0477827 |
| RPL23 | ribosomal protein L23 | -0.0475896 |
| NHSL1 | NHS-like 1 | -0.0474233 |
| RPS19 | ribosomal protein S19 | -0.0473827 |
| RPL35A | ribosomal protein L35a | -0.0471417 |
| ANK2 | ankyrin 2, neuronal | -0.0463839 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0454129 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0445713 |
| ZNF292 | zinc finger protein 292 | -0.0441194 |
| ENO1 | enolase 1, (alpha) | -0.0440739 |
| B2M | beta-2-microglobulin | -0.0440089 |
| RPL31 | ribosomal protein L31 | -0.0437323 |
| RPL36 | ribosomal protein L36 | -0.0435139 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0433802 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0433242 |
| APP | amyloid beta (A4) precursor protein | -0.0430345 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0429997 |
| SMYD3 | SET and MYND domain containing 3 | -0.0425358 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.042486 |
| RPL12 | ribosomal protein L12 | -0.0419632 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0411537 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0409242 |
| STAG2 | stromal antigen 2 | -0.0408666 |
| RPL19 | ribosomal protein L19 | -0.040771 |
| HDAC9 | histone deacetylase 9 | -0.0404031 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0402264 |
| PCDH9 | protocadherin 9 | -0.0401061 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0395855 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0392681 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0389363 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0388252 |
| DEK | DEK proto-oncogene | -0.0382181 |
| RTN4 | reticulon 4 | -0.0382076 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0371566 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0371349 |
| NFIA | nuclear factor I/A | -0.0367498 |
| RPL37 | ribosomal protein L37 | -0.0366393 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0366178 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0365749 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0365487 |
| RPL30 | ribosomal protein L30 | -0.0361655 |
| TMSB4X | thymosin beta 4, X-linked | -0.03609 |
| RDX | radixin | -0.0358488 |
| RPS27A | ribosomal protein S27a | -0.0357605 |
| CALR | calreticulin | -0.0356423 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0355247 |
| RPS6 | ribosomal protein S6 | -0.0354914 |
| ACTN4 | actinin, alpha 4 | -0.0349053 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0347142 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0346418 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0344824 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0344555 |
| RPS5 | ribosomal protein S5 | -0.0344526 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0343953 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0337073 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0336371 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0334044 |
| RPS8 | ribosomal protein S8 | -0.0332222 |
| RPL26 | ribosomal protein L26 | -0.0330733 |
| CDH19 | cadherin 19, type 2 | -0.033062 |
| ZNF217 | zinc finger protein 217 | -0.0330047 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0325673 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0325365 |
