| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bendamustine perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bendamustine_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.130208 |
| TMSB4X | thymosin beta 4, X-linked | 0.0882552 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0838008 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0778697 |
| PRELID2 | PRELI domain containing 2 | 0.0682618 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0666107 |
| PGK1 | phosphoglycerate kinase 1 | 0.0635989 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0626874 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.060738 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0595658 |
| FLNB | filamin B, beta | 0.0593858 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0569034 |
| ZNF292 | zinc finger protein 292 | 0.0519306 |
| RBM39 | RNA binding motif protein 39 | 0.0511422 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0505115 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0498977 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0496399 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0487016 |
| NCKAP1 | NCK-associated protein 1 | 0.0451891 |
| TXNRD1 | thioredoxin reductase 1 | 0.045068 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0447298 |
| CDC73 | cell division cycle 73 | 0.043481 |
| AHNAK | AHNAK nucleoprotein | 0.0432647 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0432422 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.041924 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0413918 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0408938 |
| B2M | beta-2-microglobulin | 0.0408129 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0406639 |
| SMYD3 | SET and MYND domain containing 3 | 0.0406105 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0395062 |
| EGFR | epidermal growth factor receptor | 0.0390613 |
| S100A6 | S100 calcium binding protein A6 | 0.0390356 |
| ANK2 | ankyrin 2, neuronal | 0.0387787 |
| ECT2 | epithelial cell transforming 2 | 0.0378651 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0377271 |
| LDHA | lactate dehydrogenase A | 0.0372656 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0366769 |
| EZR | ezrin | 0.0361012 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.03586 |
| SQSTM1 | sequestosome 1 | 0.0353832 |
| RTN4 | reticulon 4 | 0.0352174 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0348426 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0347912 |
| GOLGA4 | golgin A4 | 0.0347068 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0346268 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0333023 |
| PYGB | phosphorylase, glycogen; brain | 0.0331376 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0331294 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0328075 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0324025 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0322999 |
| PTK2 | protein tyrosine kinase 2 | 0.0316714 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0314456 |
| ENO1 | enolase 1, (alpha) | 0.0307106 |
| NUP58 | nucleoporin 58 | 0.0305438 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0294953 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0293699 |
| CCNL1 | cyclin L1 | 0.0292261 |
| PHF3 | PHD finger protein 3 | 0.0291824 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0291331 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0290662 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.028795 |
| QKI | QKI, KH domain containing, RNA binding | 0.0285914 |
| PCBP2 | poly(rC) binding protein 2 | 0.0283945 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0283813 |
| HDLBP | high density lipoprotein binding protein | 0.0283211 |
| RPL12 | ribosomal protein L12 | 0.0278722 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0278335 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0277241 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0276799 |
| NBAS | neuroblastoma amplified sequence | 0.0268489 |
| SMNDC1 | survival motor neuron domain containing 1 | 0.026793 |
| RNF145 | ring finger protein 145 | 0.0266001 |
| VCL | vinculin | 0.0265427 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0262219 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0260214 |
| MATR3 | matrin 3 | 0.0260142 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0255256 |
| OGA | O-GlcNAcase | 0.025512 |
| ZNF217 | zinc finger protein 217 | 0.0250611 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0246818 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0245472 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0243306 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0241294 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0240313 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.023958 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.023766 |
| CORO1C | coronin, actin binding protein, 1C | 0.023762 |
| RPL11 | ribosomal protein L11 | 0.0235087 |
| RPL13A | ribosomal protein L13a | 0.0234859 |
| TNPO1 | transportin 1 | 0.0234586 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.02344 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0233352 |
| XPO1 | exportin 1 | 0.0232209 |
| CEP95 | centrosomal protein 95kDa | 0.0230006 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0229011 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0227971 |
| UBQLN1 | ubiquilin 1 | 0.0227348 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0226994 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.130723 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.106515 |
| BMP10 | bone morphogenetic protein 10 | -0.0696348 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.059648 |
| PTMA | prothymosin, alpha | -0.0585807 |
| MKI67 | marker of proliferation Ki-67 | -0.0548207 |
| CENPF | centromere protein F, 350/400kDa | -0.0547096 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0539144 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0531364 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0490375 |
| FOXP1 | forkhead box P1 | -0.0473059 |
| RPS8 | ribosomal protein S8 | -0.0444018 |
| DIAPH3 | diaphanous-related formin 3 | -0.0426706 |
| NAV2 | neuron navigator 2 | -0.0406303 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.037295 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0357545 |
| DEK | DEK proto-oncogene | -0.0298104 |
| HDAC9 | histone deacetylase 9 | -0.0297555 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0289371 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0248582 |
| HMGB1 | high mobility group box 1 | -0.0247229 |
| GSE1 | Gse1 coiled-coil protein | -0.023594 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0234138 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0229207 |
| TJP1 | tight junction protein 1 | -0.0225457 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0219277 |
| ATN1 | atrophin 1 | -0.0218057 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0215944 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0214108 |
| TPX2 | TPX2, microtubule-associated | -0.0213769 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0213445 |
| IGF2 | insulin-like growth factor 2 | -0.0209462 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0207143 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0204397 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0201178 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0199736 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0199365 |
| HJURP | Holliday junction recognition protein | -0.0198004 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0196704 |
| CUX1 | cut-like homeobox 1 | -0.0195496 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0194607 |
| PDE7B | phosphodiesterase 7B | -0.0188804 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0188646 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.01872 |
| FUS | FUS RNA binding protein | -0.0184608 |
| RPLP1 | ribosomal protein, large, P1 | -0.0184534 |
| KIF14 | kinesin family member 14 | -0.0179648 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0179456 |
| AFG2A | AFG2 AAA ATPase homolog A | -0.0175041 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0174699 |
| GLI2 | GLI family zinc finger 2 | -0.0174599 |
| CENPE | centromere protein E, 312kDa | -0.0174049 |
| RPS10 | ribosomal protein S10 | -0.0173126 |
| EMP3 | epithelial membrane protein 3 | -0.0172927 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0172248 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0169574 |
| ACTN4 | actinin, alpha 4 | -0.0168703 |
| AEBP2 | AE binding protein 2 | -0.0165014 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0161589 |
| GLI3 | GLI family zinc finger 3 | -0.0159933 |
| RRM2 | ribonucleotide reductase M2 | -0.015907 |
| GPHN | gephyrin | -0.0157953 |
| MT2A | metallothionein 2A | -0.0155948 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0155867 |
| EXOC2 | exocyst complex component 2 | -0.015533 |
| CCND1 | cyclin D1 | -0.0154583 |
| RPL34 | ribosomal protein L34 | -0.0154485 |
| ITGA10 | integrin, alpha 10 | -0.0152861 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) | -0.015227 |
| ZNF609 | zinc finger protein 609 | -0.015219 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0151978 |
| RPS11 | ribosomal protein S11 | -0.0151847 |
| SGO2 | shugoshin 2 | -0.0151704 |
| KIF18B | kinesin family member 18B | -0.0151599 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0150049 |
| GTSE1 | G-2 and S-phase expressed 1 | -0.0149133 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0146142 |
| TLE5 | TLE family member 5, transcriptional modulator | -0.0145783 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like | -0.0144239 |
| SOGA1 | suppressor of glucose, autophagy associated 1 | -0.0140504 |
| FOXA2 | forkhead box A2 | -0.0139944 |
| GATAD2A | GATA zinc finger domain containing 2A | -0.0139625 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0139583 |
| RPL8 | ribosomal protein L8 | -0.0139578 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0139314 |
| SON | SON DNA binding protein | -0.0138929 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0137851 |
| CIP2A | cellular inhibitor of PP2A | -0.0137742 |
| ANLN | anillin, actin binding protein | -0.013696 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | -0.0136 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0135698 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.0135436 |
| RPS15 | ribosomal protein S15 | -0.0135317 |
| RPL35A | ribosomal protein L35a | -0.0135296 |
| MYADM | myeloid-associated differentiation marker | -0.0135267 |
| DENND5B | DENN/MADD domain containing 5B | -0.013434 |
| ONECUT2 | one cut homeobox 2 | -0.0133045 |
| PRR11 | proline rich 11 | -0.0132698 |
| NEBL | nebulette | -0.0131613 |
| IRX2 | iroquois homeobox 2 | -0.0131111 |
