| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bendamustine perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bendamustine_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.119386 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0929504 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0882623 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0798774 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0770078 |
| CENPF | centromere protein F, 350/400kDa | 0.0705174 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0698112 |
| POTEF | POTE ankyrin domain family, member F | 0.0667472 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0599669 |
| FN1 | fibronectin 1 | 0.0578396 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0552097 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0544331 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0541697 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0500704 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0489583 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0488482 |
| MKI67 | marker of proliferation Ki-67 | 0.0481856 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0477443 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0460736 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0454996 |
| B2M | beta-2-microglobulin | 0.0451851 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0448785 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0437908 |
| PCBP2 | poly(rC) binding protein 2 | 0.0430663 |
| ANLN | anillin, actin binding protein | 0.0421028 |
| MSN | moesin | 0.0407042 |
| CALD1 | caldesmon 1 | 0.0396929 |
| ARRDC3 | arrestin domain containing 3 | 0.039423 |
| TXNRD1 | thioredoxin reductase 1 | 0.038995 |
| TPX2 | TPX2, microtubule-associated | 0.0385707 |
| THBS1 | thrombospondin 1 | 0.0381935 |
| DIAPH3 | diaphanous-related formin 3 | 0.0361119 |
| ATP13A3 | ATPase type 13A3 | 0.0355064 |
| SRGN | serglycin | 0.0351584 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0326771 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0326032 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0322718 |
| DSTN | destrin (actin depolymerizing factor) | 0.0322526 |
| KIF4A | kinesin family member 4A | 0.0311254 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0294911 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0290489 |
| SDC4 | syndecan 4 | 0.0279876 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0271809 |
| TPM4 | tropomyosin 4 | 0.0270214 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0266938 |
| WTAP | Wilms tumor 1 associated protein | 0.0265122 |
| RTN4 | reticulon 4 | 0.0256668 |
| SET | SET nuclear proto-oncogene | 0.0254699 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0251085 |
| NUP58 | nucleoporin 58 | 0.0246947 |
| CCNL1 | cyclin L1 | 0.0246584 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0245883 |
| EZR | ezrin | 0.0243977 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0239038 |
| TPM3 | tropomyosin 3 | 0.0237246 |
| TMEM123 | transmembrane protein 123 | 0.0236509 |
| SERINC1 | serine incorporator 1 | 0.0234262 |
| XPO1 | exportin 1 | 0.0228834 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0227708 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0227616 |
| MATR3 | matrin 3 | 0.022628 |
| DEK | DEK proto-oncogene | 0.0224613 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0221809 |
| GOLGA4 | golgin A4 | 0.0220685 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0219615 |
| SNX3 | sorting nexin 3 | 0.0218939 |
| NONO | non-POU domain containing, octamer-binding | 0.0218573 |
| ECT2 | epithelial cell transforming 2 | 0.0211749 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0207146 |
| YBX3 | Y box binding protein 3 | 0.0205407 |
| IPO7 | importin 7 | 0.0204834 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0204494 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0202738 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0199668 |
| TGFB2 | transforming growth factor, beta 2 | 0.0199348 |
| IL6 | interleukin 6 | 0.0198799 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.019863 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0198599 |
| CKAP2 | cytoskeleton associated protein 2 | 0.019711 |
| CRY1 | cryptochrome circadian clock 1 | 0.0193884 |
| PTMA | prothymosin, alpha | 0.0193834 |
| ACTN1 | actinin, alpha 1 | 0.0193675 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0193669 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0192143 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0190577 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0185563 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0184072 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.018264 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0182342 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0182053 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0179634 |
| TKT | transketolase | 0.0178796 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0178188 |
| LIMA1 | LIM domain and actin binding 1 | 0.0178023 |
| HELZ | helicase with zinc finger | 0.0177502 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0176894 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0176017 |
| UVRAG | UV radiation resistance associated | 0.0175988 |
| HBS1L | HBS1-like translational GTPase | 0.0175571 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0174661 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.170402 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.162097 |
| GLIS3 | GLIS family zinc finger 3 | -0.135556 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.131334 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.122417 |
| HMGA2 | high mobility group AT-hook 2 | -0.119811 |
| PDE10A | phosphodiesterase 10A | -0.105744 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0947776 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0932044 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0892228 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0865659 |
| NDRG1 | N-myc downstream regulated 1 | -0.0846846 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0841348 |
| CDH13 | cadherin 13 | -0.0829947 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0776441 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0770317 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0760921 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0753844 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0741771 |
| HDAC9 | histone deacetylase 9 | -0.0726802 |
| INTS6 | integrator complex subunit 6 | -0.0696182 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.067842 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0654238 |
| EGFR | epidermal growth factor receptor | -0.0637152 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0631414 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0619495 |
| FRMD4A | FERM domain containing 4A | -0.0609325 |
| ATXN1 | ataxin 1 | -0.060151 |
| DIAPH2 | diaphanous-related formin 2 | -0.0599715 |
| GPC6 | glypican 6 | -0.0587763 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0549444 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0549105 |
| RAI14 | retinoic acid induced 14 | -0.0546684 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0540689 |
| AHNAK | AHNAK nucleoprotein | -0.0538179 |
| CD44 | CD44 molecule (Indian blood group) | -0.0523359 |
| IER3 | immediate early response 3 | -0.0514322 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.051148 |
| VIM | vimentin | -0.0505574 |
| COL5A1 | collagen, type V, alpha 1 | -0.0504312 |
| AFF3 | AF4/FMR2 family, member 3 | -0.049695 |
| TMSB10 | thymosin beta 10 | -0.0493716 |
| SMYD3 | SET and MYND domain containing 3 | -0.0481875 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0478308 |
| TMEM132D | transmembrane protein 132D | -0.0478033 |
| NABP1 | nucleic acid binding protein 1 | -0.0474554 |
| TNS3 | tensin 3 | -0.0472332 |
| NAV1 | neuron navigator 1 | -0.0466568 |
| VCL | vinculin | -0.0457628 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.044982 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0447386 |
| EFNA5 | ephrin-A5 | -0.0440185 |
| PRELID2 | PRELI domain containing 2 | -0.0440124 |
| FLNB | filamin B, beta | -0.0435471 |
| RAD51B | RAD51 paralog B | -0.0418022 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0414219 |
| FNIP1 | folliculin interacting protein 1 | -0.0413399 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0413327 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0410057 |
| HLA-A | major histocompatibility complex, class I, A | -0.0407573 |
| SQSTM1 | sequestosome 1 | -0.0406255 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0405372 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0403396 |
| HLA-B | major histocompatibility complex, class I, B | -0.0399731 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0397808 |
| ARFGEF3 | ARFGEF family member 3 | -0.0397644 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0393207 |
| CANX | calnexin | -0.0392247 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0390635 |
| FTL | ferritin, light polypeptide | -0.0382642 |
| FMNL2 | formin-like 2 | -0.0377146 |
| MMP12 | matrix metallopeptidase 12 | -0.0375554 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0356117 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0355069 |
| VEGFA | vascular endothelial growth factor A | -0.0353749 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0352965 |
| ASPH | aspartate beta-hydroxylase | -0.0352369 |
| PRKCA | protein kinase C, alpha | -0.0349234 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0348153 |
| PCBP3 | poly(rC) binding protein 3 | -0.0347106 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0340983 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0338025 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0337465 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0333173 |
| RNF213 | ring finger protein 213 | -0.033265 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0330297 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0327681 |
| EHBP1 | EH domain binding protein 1 | -0.0326255 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0323259 |
| BNC2 | basonuclin 2 | -0.0316609 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0314512 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0314151 |
| BPTF | bromodomain PHD finger transcription factor | -0.0311608 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0309883 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0306878 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0306662 |
| NCKAP5 | NCK-associated protein 5 | -0.0303312 |
| FBXO32 | F-box protein 32 | -0.0302835 |
| BICC1 | BicC family RNA binding protein 1 | -0.0302423 |
| DST | dystonin | -0.0302264 |
