| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bendamustine perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bendamustine_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.1645 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.109143 |
| ITGA1 | integrin, alpha 1 | 0.103783 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0760837 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0703731 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0698463 |
| PRELID2 | PRELI domain containing 2 | 0.0595016 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0561499 |
| SMOX | spermine oxidase | 0.0467688 |
| ASPH | aspartate beta-hydroxylase | 0.0459036 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0450349 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0444108 |
| SMAD3 | SMAD family member 3 | 0.044257 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0434108 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0431908 |
| ENO1 | enolase 1, (alpha) | 0.0382867 |
| DST | dystonin | 0.0381944 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0377084 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0375704 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0369046 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0355108 |
| FAT1 | FAT atypical cadherin 1 | 0.0340652 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0337566 |
| PGK1 | phosphoglycerate kinase 1 | 0.0315156 |
| TXNIP | thioredoxin interacting protein | 0.0314815 |
| AHR | aryl hydrocarbon receptor | 0.0310816 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0309786 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0308454 |
| FAM13A | family with sequence similarity 13, member A | 0.0300385 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.029391 |
| MYOF | myoferlin | 0.0291513 |
| AFDN | afadin, adherens junction formation factor | 0.0290468 |
| TPM3 | tropomyosin 3 | 0.0288833 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0286682 |
| SMYD3 | SET and MYND domain containing 3 | 0.0285692 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0283442 |
| SFTPA2 | surfactant protein A2 | 0.0281667 |
| NAV2 | neuron navigator 2 | 0.0281413 |
| HPS3 | Hermansky-Pudlak syndrome 3 | 0.0280214 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0271806 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.02697 |
| XPO1 | exportin 1 | 0.0264598 |
| RUNX2 | runt-related transcription factor 2 | 0.0264219 |
| TXNRD1 | thioredoxin reductase 1 | 0.0263999 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0262087 |
| ANXA5 | annexin A5 | 0.0260703 |
| ANXA11 | annexin A11 | 0.025848 |
| POTEF | POTE ankyrin domain family, member F | 0.0256327 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0247757 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0245796 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0245759 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0235059 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0235009 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0232683 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0231666 |
| TMEM156 | transmembrane protein 156 | 0.0230052 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0229552 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0227657 |
| EREG | epiregulin | 0.0226366 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0226 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0222039 |
| VEGFC | vascular endothelial growth factor C | 0.0221725 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0220985 |
| MYEF2 | myelin expression factor 2 | 0.0220792 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0220095 |
| CENPF | centromere protein F, 350/400kDa | 0.0219843 |
| S100A10 | S100 calcium binding protein A10 | 0.0219284 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0218309 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0215564 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0213685 |
| SERINC3 | serine incorporator 3 | 0.0212753 |
| STC2 | stanniocalcin 2 | 0.0212486 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.021164 |
| DENND1A | DENN/MADD domain containing 1A | 0.0211073 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0209978 |
| MEF2A | myocyte enhancer factor 2A | 0.0209922 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0209364 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0209002 |
| TLN1 | talin 1 | 0.0207029 |
| ANLN | anillin, actin binding protein | 0.0207007 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0206113 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0204496 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0204066 |
| RAD51B | RAD51 paralog B | 0.0203423 |
| CD109 | CD109 molecule | 0.0203393 |
| USP12 | ubiquitin specific peptidase 12 | 0.0203154 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0200727 |
| WDR33 | WD repeat domain 33 | 0.0200441 |
| ITGB5 | integrin, beta 5 | 0.019955 |
| RANBP2 | RAN binding protein 2 | 0.0199363 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0198729 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0198688 |
| CEP170 | centrosomal protein 170kDa | 0.0198117 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0197868 |
| INSIG2 | insulin induced gene 2 | 0.0195868 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.019255 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0190528 |
| STK10 | serine/threonine kinase 10 | 0.018988 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0188837 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0188808 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.324163 |
| MT2A | metallothionein 2A | -0.121922 |
| EXT1 | exostosin glycosyltransferase 1 | -0.114304 |
| TMSB10 | thymosin beta 10 | -0.0780498 |
| VCL | vinculin | -0.0780215 |
| NDRG1 | N-myc downstream regulated 1 | -0.0687002 |
| NTN4 | netrin 4 | -0.0685346 |
| FTL | ferritin, light polypeptide | -0.0595563 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0593559 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0581814 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0562542 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0558777 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0502796 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0501125 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0483994 |
| NRP1 | neuropilin 1 | -0.0482521 |
| EGR1 | early growth response 1 | -0.0474425 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0455201 |
| VIM | vimentin | -0.0452074 |
| KSR1 | kinase suppressor of ras 1 | -0.0442021 |
| PTMA | prothymosin, alpha | -0.0440706 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0433159 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0432499 |
| GOLGA4 | golgin A4 | -0.0428512 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0418318 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0401 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.039352 |
| RAB10 | RAB10, member RAS oncogene family | -0.0387006 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0383364 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0382223 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0380665 |
| RPS19 | ribosomal protein S19 | -0.0379435 |
| TMEM165 | transmembrane protein 165 | -0.0376952 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0376091 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0371823 |
| VEGFA | vascular endothelial growth factor A | -0.0371383 |
| RPL26 | ribosomal protein L26 | -0.0370387 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0365727 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.036378 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0354734 |
| FNBP1 | formin binding protein 1 | -0.0352195 |
| NPAS2 | neuronal PAS domain protein 2 | -0.034896 |
| PALLD | palladin, cytoskeletal associated protein | -0.0345716 |
| VMP1 | vacuole membrane protein 1 | -0.0341803 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0340559 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0339668 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0339573 |
| NXN | nucleoredoxin | -0.0332855 |
| FAM193A | family with sequence similarity 193, member A | -0.0330459 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.032945 |
| RPL37A | ribosomal protein L37a | -0.0325014 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0320821 |
| SYT1 | synaptotagmin I | -0.031995 |
| RPS6 | ribosomal protein S6 | -0.0317437 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0306933 |
| RPLP1 | ribosomal protein, large, P1 | -0.0305832 |
| SETD5 | SET domain containing 5 | -0.0302213 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0299404 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0296443 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0293536 |
| BRD2 | bromodomain containing 2 | -0.028946 |
| ADIPOR2 | adiponectin receptor 2 | -0.0287606 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0284037 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0276434 |
| RPL36 | ribosomal protein L36 | -0.0276404 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0275703 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0275493 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0271609 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0269713 |
| ETNK1 | ethanolamine kinase 1 | -0.0267119 |
| TOP1 | topoisomerase (DNA) I | -0.0265095 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0264766 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0264219 |
| RPL35A | ribosomal protein L35a | -0.0263992 |
| GLCCI1 | glucocorticoid induced 1 | -0.0258356 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0257457 |
| S100A9 | S100 calcium binding protein A9 | -0.0255017 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0253823 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0252679 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0251975 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.025168 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.025127 |
| PIM3 | Pim-3 proto-oncogene, serine/threonine kinase | -0.0248256 |
| EPN2 | epsin 2 | -0.024729 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | -0.0243582 |
| ZNF644 | zinc finger protein 644 | -0.0243087 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0242782 |
| GNAS | GNAS complex locus | -0.024205 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0241775 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0241258 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0240744 |
| RPLP2 | ribosomal protein, large, P2 | -0.0239364 |
| MT1X | metallothionein 1X | -0.0238057 |
| LMNA | lamin A/C | -0.0237401 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0232318 |
| RPS12 | ribosomal protein S12 | -0.023202 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0231575 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0230525 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0228171 |
| FHL2 | four and a half LIM domains 2 | -0.0227303 |
