| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benproperine (phosphate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Benproperine (phosphate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.152911 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0829883 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0690798 |
| SUCNR1 | succinate receptor 1 | 0.0647478 |
| FN1 | fibronectin 1 | 0.0646343 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0560457 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.0546988 |
| CDH13 | cadherin 13 | 0.0541579 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.047103 |
| PLAT | plasminogen activator, tissue | 0.0470546 |
| POTEF | POTE ankyrin domain family, member F | 0.0462644 |
| ASPH | aspartate beta-hydroxylase | 0.0415557 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0414382 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0403187 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0393068 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0391558 |
| PODXL | podocalyxin-like | 0.0378945 |
| MAP1B | microtubule-associated protein 1B | 0.0376467 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0361869 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0350421 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.032071 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0313231 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.030767 |
| DCLK2 | doublecortin-like kinase 2 | 0.030727 |
| PRSS23 | protease, serine, 23 | 0.0300427 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0298104 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0289468 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0288446 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0275435 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0272747 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0269266 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0257164 |
| NEK7 | NIMA-related kinase 7 | 0.0248139 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0243516 |
| MED13L | mediator complex subunit 13-like | 0.0242857 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0242512 |
| PLXNA2 | plexin A2 | 0.023051 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0227212 |
| LRRC17 | leucine rich repeat containing 17 | 0.0222127 |
| TPM1 | tropomyosin 1 (alpha) | 0.0221779 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.022109 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0217667 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0214152 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0211934 |
| MSI2 | musashi RNA-binding protein 2 | 0.0204895 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | 0.020376 |
| MSN | moesin | 0.020288 |
| CYTH3 | cytohesin 3 | 0.0198812 |
| XPO1 | exportin 1 | 0.0196895 |
| SP3 | Sp3 transcription factor | 0.0195323 |
| COL5A1 | collagen, type V, alpha 1 | 0.0189833 |
| KRT81 | keratin 81, type II | 0.0184262 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0182734 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0181071 |
| CENPF | centromere protein F, 350/400kDa | 0.0180388 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0177783 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0175339 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0174195 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.017277 |
| FLT1 | fms-related tyrosine kinase 1 | 0.0168966 |
| TOX | thymocyte selection-associated high mobility group box | 0.016788 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0167128 |
| MCL1 | myeloid cell leukemia 1 | 0.0166381 |
| SPAG9 | sperm associated antigen 9 | 0.0163281 |
| DIAPH3 | diaphanous-related formin 3 | 0.016262 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0161906 |
| C12ORF75 | chromosome 12 open reading frame 75 | 0.016053 |
| SRPK2 | SRSF protein kinase 2 | 0.0160372 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0157828 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0157246 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0157103 |
| NCKAP1 | NCK-associated protein 1 | 0.0156256 |
| ATP13A3 | ATPase type 13A3 | 0.0154094 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0153987 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0153009 |
| DST | dystonin | 0.0152795 |
| PDE10A | phosphodiesterase 10A | 0.0150119 |
| FNIP2 | folliculin interacting protein 2 | 0.0148414 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0147383 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0145449 |
| PKM | pyruvate kinase, muscle | 0.0144721 |
| ZNF148 | zinc finger protein 148 | 0.0144377 |
| SLC39A11 | solute carrier family 39, member 11 | 0.013979 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0139086 |
| QKI | QKI, KH domain containing, RNA binding | 0.013882 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0137662 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0137261 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0137201 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.013505 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.013387 |
| CEP170 | centrosomal protein 170kDa | 0.0133751 |
| USP47 | ubiquitin specific peptidase 47 | 0.0133631 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0132846 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0132117 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0132086 |
| TFG | TRK-fused gene | 0.0131192 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0131041 |
| JAK2 | Janus kinase 2 | 0.0130904 |
| RYK | receptor-like tyrosine kinase | 0.0130889 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0130059 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.128958 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.107082 |
| LOX | lysyl oxidase | -0.105565 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0987947 |
| VIM | vimentin | -0.0968455 |
| TMSB10 | thymosin beta 10 | -0.0893068 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0871212 |
| LOXL2 | lysyl oxidase-like 2 | -0.0868895 |
| NDRG1 | N-myc downstream regulated 1 | -0.084258 |
| SQSTM1 | sequestosome 1 | -0.0724652 |
| ANXA2 | annexin A2 | -0.0641054 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0638763 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0558675 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0558124 |
| S100A6 | S100 calcium binding protein A6 | -0.0531079 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0506043 |
| MT2A | metallothionein 2A | -0.0493757 |
| CANX | calnexin | -0.0490046 |
| STC1 | stanniocalcin 1 | -0.0485962 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0482951 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0458683 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0452853 |
| LMNA | lamin A/C | -0.0443214 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.041665 |
| UBC | ubiquitin C | -0.0408641 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0402768 |
| B2M | beta-2-microglobulin | -0.0397901 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0397124 |
| PTMA | prothymosin, alpha | -0.0391501 |
| HLA-B | major histocompatibility complex, class I, B | -0.0387884 |
| CD44 | CD44 molecule (Indian blood group) | -0.035818 |
| THBS2 | thrombospondin 2 | -0.0348547 |
| FTL | ferritin, light polypeptide | -0.0342402 |
| CSTB | cystatin B (stefin B) | -0.0340112 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0331103 |
| COL1A2 | collagen, type I, alpha 2 | -0.0329647 |
| OGA | O-GlcNAcase | -0.0328163 |
| LDHA | lactate dehydrogenase A | -0.0327965 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0320396 |
| AHNAK | AHNAK nucleoprotein | -0.0320152 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0312607 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0305518 |
| S100A10 | S100 calcium binding protein A10 | -0.0300126 |
| HDLBP | high density lipoprotein binding protein | -0.029413 |
| HLA-E | major histocompatibility complex, class I, E | -0.0291047 |
| RPS3 | ribosomal protein S3 | -0.0284493 |
| RPL12 | ribosomal protein L12 | -0.0275592 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0270473 |
| PRELID2 | PRELI domain containing 2 | -0.0268826 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0266485 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.026003 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0257499 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0250342 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0246545 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0246219 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0243683 |
| GLIS3 | GLIS family zinc finger 3 | -0.0243103 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0238221 |
| HLA-C | major histocompatibility complex, class I, C | -0.0236281 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0235343 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0232492 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0225664 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0225243 |
| CALR | calreticulin | -0.0222148 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.0221593 |
| RPL23 | ribosomal protein L23 | -0.022085 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0216697 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0216693 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0214352 |
| CAVIN1 | caveolae associated protein 1 | -0.0212862 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0212234 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0211975 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0211795 |
| HIP1 | huntingtin interacting protein 1 | -0.0207913 |
| RPL7A | ribosomal protein L7a | -0.0207307 |
| MYADM | myeloid-associated differentiation marker | -0.0206498 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0206124 |
| RPLP1 | ribosomal protein, large, P1 | -0.0205566 |
| GOLGA4 | golgin A4 | -0.0205118 |
| FNIP1 | folliculin interacting protein 1 | -0.020505 |
| OPTN | optineurin | -0.0204209 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0200717 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.019947 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -0.019781 |
| RPL37A | ribosomal protein L37a | -0.0197014 |
| ARFGEF3 | ARFGEF family member 3 | -0.0194825 |
| RPS19 | ribosomal protein S19 | -0.0194523 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0194344 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.0194216 |
| STK10 | serine/threonine kinase 10 | -0.019421 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0193024 |
| ACTG1 | actin gamma 1 | -0.0190789 |
| MX2 | MX dynamin-like GTPase 2 | -0.0190432 |
| COL5A2 | collagen, type V, alpha 2 | -0.018879 |
| MYO9A | myosin IXA | -0.0187778 |
| ZBTB7C | zinc finger and BTB domain containing 7C | -0.0186647 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0184812 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.018479 |
| SEPTIN9 | septin 9 | -0.0184334 |
| RNF169 | ring finger protein 169 | -0.0184264 |
