| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benproperine (phosphate) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Benproperine (phosphate)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.066447 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0576967 |
| NAV2 | neuron navigator 2 | 0.0451997 |
| G0S2 | G0/G1 switch 2 | 0.0431444 |
| CBX3 | chromobox homolog 3 | 0.0409502 |
| CENPF | centromere protein F, 350/400kDa | 0.0370006 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0356177 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0311842 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0305783 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0286861 |
| USP3 | ubiquitin specific peptidase 3 | 0.0275791 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0266316 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0253122 |
| RAB10 | RAB10, member RAS oncogene family | 0.0251468 |
| CENPE | centromere protein E, 312kDa | 0.0248686 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0241648 |
| CRY1 | cryptochrome circadian clock 1 | 0.0239696 |
| TPX2 | TPX2, microtubule-associated | 0.0232542 |
| MTDH | metadherin | 0.0230643 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0225761 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0225321 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0223983 |
| FMNL2 | formin-like 2 | 0.022377 |
| DENND4A | DENN/MADD domain containing 4A | 0.0221742 |
| RPL28 | ribosomal protein L28 | 0.0221662 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0219669 |
| RDX | radixin | 0.0217404 |
| MKI67 | marker of proliferation Ki-67 | 0.021088 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0210217 |
| RAB21 | RAB21, member RAS oncogene family | 0.0208885 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0208871 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0207938 |
| CADM1 | cell adhesion molecule 1 | 0.0207815 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0207496 |
| CCDC50 | coiled-coil domain containing 50 | 0.0202265 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0202191 |
| PHF20L1 | PHD finger protein 20-like 1 | 0.0200161 |
| NXN | nucleoredoxin | 0.0196625 |
| KIF4A | kinesin family member 4A | 0.019641 |
| ADM | adrenomedullin | 0.0196354 |
| MATR3 | matrin 3 | 0.019558 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0195301 |
| GOLGB1 | golgin B1 | 0.0187177 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0185922 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0185903 |
| LYST | lysosomal trafficking regulator | 0.018561 |
| TPM3 | tropomyosin 3 | 0.0183065 |
| SRPK2 | SRSF protein kinase 2 | 0.0177022 |
| CKAP4 | cytoskeleton-associated protein 4 | 0.017672 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0175191 |
| TJP2 | tight junction protein 2 | 0.0174718 |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.0174454 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | 0.0171546 |
| LYPLA1 | lysophospholipase I | 0.0169806 |
| PLPP3 | phospholipid phosphatase 3 | 0.0168825 |
| ERBIN | erbb2 interacting protein | 0.0168286 |
| ZNF609 | zinc finger protein 609 | 0.0167693 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0165424 |
| SLAIN2 | SLAIN motif family, member 2 | 0.0164828 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0164029 |
| KLHDC10 | kelch domain containing 10 | 0.0163084 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0162384 |
| NAA35 | N(alpha)-acetyltransferase 35, NatC auxiliary subunit | 0.0160041 |
| PAX8 | paired box 8 | 0.0159425 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0156753 |
| PDS5B | PDS5 cohesin associated factor B | 0.0156033 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 0.0154495 |
| MYO10 | myosin X | 0.0154262 |
| TKT | transketolase | 0.0152973 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0151738 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.0151296 |
| IL32 | interleukin 32 | 0.0150916 |
| RAB18 | RAB18, member RAS oncogene family | 0.0150616 |
| ATP13A3 | ATPase type 13A3 | 0.015057 |
| MGLL | monoglyceride lipase | 0.0149194 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0148865 |
| UBAP2 | ubiquitin associated protein 2 | 0.014783 |
| COX7B | cytochrome c oxidase subunit VIIb | 0.014782 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0146845 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.0145452 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | 0.0144917 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0144334 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0143485 |
| HDIP1 | HDAC and MIER1 interacting protein 1 | 0.014274 |
| SARNP | SAP domain containing ribonucleoprotein | 0.0142627 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0142457 |
| RBM25 | RNA binding motif protein 25 | 0.0142368 |
| TAOK1 | TAO kinase 1 | 0.0142229 |
| ANLN | anillin, actin binding protein | 0.0142182 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0141677 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0141565 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0141541 |
| YBX3 | Y box binding protein 3 | 0.0141227 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0139001 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0138397 |
| MPHOSPH10 | M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) | 0.0138286 |
| URI1 | URI1, prefoldin-like chaperone | 0.0138107 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.0137218 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0136567 |
| CDK14 | cyclin-dependent kinase 14 | 0.0136545 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.134288 |
| EXT1 | exostosin glycosyltransferase 1 | -0.102394 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0989302 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.083857 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0704022 |
| SMAD3 | SMAD family member 3 | -0.0693222 |
| NDRG1 | N-myc downstream regulated 1 | -0.0679002 |
| GPC6 | glypican 6 | -0.067484 |
| VCL | vinculin | -0.0637537 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.063414 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0633671 |
| FAT1 | FAT atypical cadherin 1 | -0.0602955 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0587557 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.057938 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0554749 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.054004 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0539681 |
| ANXA2 | annexin A2 | -0.0474038 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0472288 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0456152 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0449327 |
| GLIS3 | GLIS family zinc finger 3 | -0.0417445 |
| FAM107B | family with sequence similarity 107, member B | -0.0416193 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0412074 |
| NRP2 | neuropilin 2 | -0.0410976 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0405978 |
| RUNX1 | runt-related transcription factor 1 | -0.0403073 |
| CA12 | carbonic anhydrase XII | -0.0393824 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0392231 |
| RNF213 | ring finger protein 213 | -0.0391936 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0389729 |
| CD44 | CD44 molecule (Indian blood group) | -0.0378327 |
| MYOF | myoferlin | -0.0378264 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0378073 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0375437 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0371184 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0368984 |
| SEC24D | SEC24 family member D | -0.0367528 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0367381 |
| CALU | calumenin | -0.0361286 |
| PLK2 | polo-like kinase 2 | -0.0350616 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0350615 |
| ANXA5 | annexin A5 | -0.0349652 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0344413 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0338297 |
| RPS12 | ribosomal protein S12 | -0.033459 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0327208 |
| SP3 | Sp3 transcription factor | -0.0326784 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0320571 |
| SLTM | SAFB-like, transcription modulator | -0.032045 |
| RPS2 | ribosomal protein S2 | -0.0319139 |
| RPLP2 | ribosomal protein, large, P2 | -0.0316929 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0316105 |
| TLN1 | talin 1 | -0.0315952 |
| TUFT1 | tuftelin 1 | -0.0309697 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.030954 |
| OSMR | oncostatin M receptor | -0.0308435 |
| FHL2 | four and a half LIM domains 2 | -0.0303851 |
| CUX1 | cut-like homeobox 1 | -0.0301259 |
| RPLP1 | ribosomal protein, large, P1 | -0.0300482 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.029913 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0297568 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0295944 |
| CANX | calnexin | -0.0292217 |
| VIM | vimentin | -0.0291927 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.029033 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0289664 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.028784 |
| LIMA1 | LIM domain and actin binding 1 | -0.028736 |
| PALLD | palladin, cytoskeletal associated protein | -0.0284844 |
| RPL7A | ribosomal protein L7a | -0.0283405 |
| RIC1 | RAB6A GEF complex partner 1 | -0.028109 |
| WRN | Werner syndrome, RecQ helicase-like | -0.0280597 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0278719 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0278366 |
| FAM13A | family with sequence similarity 13, member A | -0.0278039 |
| TRIM56 | tripartite motif containing 56 | -0.027586 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0275786 |
| TLE4 | transducin-like enhancer of split 4 | -0.0271471 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0270695 |
| EFNA5 | ephrin-A5 | -0.0269481 |
| RTN4 | reticulon 4 | -0.0269402 |
| MSR1 | macrophage scavenger receptor 1 | -0.0268234 |
| TENM3 | teneurin transmembrane protein 3 | -0.0267108 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0264263 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0262447 |
| ENO1 | enolase 1, (alpha) | -0.0261925 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0261752 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0261513 |
| TPM1 | tropomyosin 1 (alpha) | -0.0261022 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.026002 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0258661 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0256798 |
| PLSCR1 | phospholipid scramblase 1 | -0.0253338 |
| TMEM165 | transmembrane protein 165 | -0.0250164 |
| RPS6 | ribosomal protein S6 | -0.024912 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0248545 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0247404 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0247002 |
| ASPH | aspartate beta-hydroxylase | -0.0246689 |
