| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benproperine (phosphate) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Benproperine (phosphate)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0606987 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0463801 |
| TMEM123 | transmembrane protein 123 | 0.0268734 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0242664 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0238982 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0222027 |
| PGK1 | phosphoglycerate kinase 1 | 0.0208084 |
| ZNF292 | zinc finger protein 292 | 0.0191809 |
| FADS2 | fatty acid desaturase 2 | 0.0191727 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0184993 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | 0.017539 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0149648 |
| SQLE | squalene epoxidase | 0.0143076 |
| FASN | fatty acid synthase | 0.013823 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0137081 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0135933 |
| KIF16B | kinesin family member 16B | 0.0134465 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0134031 |
| FAM13A | family with sequence similarity 13, member A | 0.0131936 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0130047 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0127392 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0124676 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.01208 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0116161 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0105718 |
| FDPS | farnesyl diphosphate synthase | 0.0105127 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0104913 |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.0102348 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0102134 |
| RESF1 | retroelement silencing factor 1 | 0.0102016 |
| TUG1 | taurine up-regulated 1 (non-protein coding) | 0.0101385 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | 0.00988255 |
| ITGB6 | integrin, beta 6 | 0.00982418 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0097912 |
| PCBP2 | poly(rC) binding protein 2 | 0.00965192 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0090968 |
| KLHL24 | kelch-like family member 24 | 0.00908022 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A | 0.00897347 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.00877339 |
| DUSP4 | dual specificity phosphatase 4 | 0.00877314 |
| TAPBP | TAP binding protein (tapasin) | 0.00876052 |
| USP3 | ubiquitin specific peptidase 3 | 0.00854952 |
| INSIG1 | insulin induced gene 1 | 0.00853344 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.00847842 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00837297 |
| EEIG1 | estrogen-induced osteoclastogenesis regulator 1 | 0.00830146 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.00828283 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.00808154 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) | 0.00805321 |
| CLDN4 | claudin 4 | 0.00802436 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.00785018 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.00781393 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.00768486 |
| SENP7 | SUMO1/sentrin specific peptidase 7 | 0.00751073 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.00745687 |
| CDC73 | cell division cycle 73 | 0.00744408 |
| RAB18 | RAB18, member RAS oncogene family | 0.00739763 |
| ECT2 | epithelial cell transforming 2 | 0.0073752 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.00732292 |
| GOLGA2 | golgin A2 | 0.00731255 |
| CEP170 | centrosomal protein 170kDa | 0.0072772 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.00705125 |
| FBXO42 | F-box protein 42 | 0.00699723 |
| MVD | mevalonate (diphospho) decarboxylase | 0.00696786 |
| WWP1 | WW domain containing E3 ubiquitin protein ligase 1 | 0.00694602 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00694006 |
| KRT8 | keratin 8, type II | 0.00685688 |
| SRP54 | signal recognition particle 54kDa | 0.00682655 |
| VIM | vimentin | 0.00681075 |
| TUBB | tubulin, beta class I | 0.00676589 |
| PRELID2 | PRELI domain containing 2 | 0.00675423 |
| TMEM135 | transmembrane protein 135 | 0.00671431 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 | 0.00668839 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.00668662 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.00665879 |
| GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 | 0.00664109 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.00656451 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.00656439 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | 0.00654989 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.00648759 |
| TMEM41B | transmembrane protein 41B | 0.00640991 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.00637911 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.00632642 |
| SLMAP | sarcolemma associated protein | 0.00625381 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.00621144 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00620346 |
| GMPS | guanine monphosphate synthase | 0.00612855 |
| BCAM | basal cell adhesion molecule (Lutheran blood group) | 0.00612494 |
| PHKB | phosphorylase kinase, beta | 0.00609946 |
| RUNX2 | runt-related transcription factor 2 | 0.00605019 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.00605008 |
| ENO1 | enolase 1, (alpha) | 0.00602565 |
| CARD16 | caspase recruitment domain family, member 16 | 0.00601794 |
| LPIN1 | lipin 1 | 0.00601422 |
| IKZF2 | IKAROS family zinc finger 2 (Helios) | 0.00600541 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00598717 |
| HDAC9 | histone deacetylase 9 | 0.00596593 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00595548 |
| GUCY1A1 | guanylate cyclase 1 soluble subunit alpha 1 | 0.00595421 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.00590793 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL19 | ribosomal protein L19 | -0.22503 |
| RPL23 | ribosomal protein L23 | -0.124918 |
| CDK12 | cyclin-dependent kinase 12 | -0.0952352 |
| CLTC | clathrin, heavy chain (Hc) | -0.0857701 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.073936 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0736454 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0694952 |
| MT2A | metallothionein 2A | -0.0693259 |
| VMP1 | vacuole membrane protein 1 | -0.0660382 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0602968 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0513916 |
| KIAA1217 | KIAA1217 | -0.0510683 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0497047 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | -0.0495635 |
| ACTG1 | actin gamma 1 | -0.0493986 |
| MCL1 | myeloid cell leukemia 1 | -0.0491682 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0485973 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.048327 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0474351 |
| NTN4 | netrin 4 | -0.0441856 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | -0.044176 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0439586 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0427254 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0426568 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0422618 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0416591 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0415398 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0413761 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0407878 |
| DUSP16 | dual specificity phosphatase 16 | -0.0404352 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0400799 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0399138 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0382566 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0379266 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0370802 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0367418 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0361366 |
| SET | SET nuclear proto-oncogene | -0.0361074 |
| B2M | beta-2-microglobulin | -0.0356921 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0352257 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0337177 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0337078 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0336994 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0333698 |
| S100A8 | S100 calcium binding protein A8 | -0.0329445 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.032653 |
| S100A9 | S100 calcium binding protein A9 | -0.0326153 |
| APP | amyloid beta (A4) precursor protein | -0.0324613 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0322402 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0321316 |
| OSMR | oncostatin M receptor | -0.0320184 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0320148 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0320051 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0315197 |
| NDRG1 | N-myc downstream regulated 1 | -0.0313219 |
| MYO1B | myosin IB | -0.0307485 |
| RPS3 | ribosomal protein S3 | -0.0305069 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0303937 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0299926 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0293355 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0290134 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0286975 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0286392 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0282937 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0282871 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.028271 |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C | -0.028181 |
| DSPP | dentin sialophosphoprotein | -0.0279661 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0276401 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0276018 |
| RPS2 | ribosomal protein S2 | -0.0273995 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0273222 |
| CAB39 | calcium binding protein 39 | -0.0272355 |
| PFDN4 | prefoldin subunit 4 | -0.0269478 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0268926 |
| VCP | valosin containing protein | -0.0264391 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0262256 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0260765 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0260265 |
| RBM39 | RNA binding motif protein 39 | -0.025859 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0257793 |
| SEPTIN9 | septin 9 | -0.0254653 |
| SLFN5 | schlafen family member 5 | -0.0253647 |
| ADAR | adenosine deaminase, RNA-specific | -0.0253589 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0251999 |
| TXNRD1 | thioredoxin reductase 1 | -0.0250768 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0249116 |
| SP100 | SP100 nuclear antigen | -0.0246865 |
| PRR11 | proline rich 11 | -0.0246742 |
| RPS8 | ribosomal protein S8 | -0.0245209 |
| RPL12 | ribosomal protein L12 | -0.0237086 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | -0.023694 |
| PTMA | prothymosin, alpha | -0.0231952 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0230775 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0230497 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0230212 |
| INSR | insulin receptor | -0.022809 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0228016 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0222794 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0222023 |
