| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benproperine (phosphate) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Benproperine (phosphate)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0491176 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0409792 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0405619 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0365041 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0336827 |
| RTN4 | reticulon 4 | 0.0310408 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0293267 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0276476 |
| MKI67 | marker of proliferation Ki-67 | 0.0276151 |
| ENO1 | enolase 1, (alpha) | 0.0276148 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0251847 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0249756 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.02426 |
| SRPK2 | SRSF protein kinase 2 | 0.0242029 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0241999 |
| PDS5A | PDS5 cohesin associated factor A | 0.0236615 |
| MED13 | mediator complex subunit 13 | 0.0236095 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0232322 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0230882 |
| PFN1 | profilin 1 | 0.0223066 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0222881 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0220803 |
| HMGA1 | high mobility group AT-hook 1 | 0.0219841 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0217942 |
| CENPF | centromere protein F, 350/400kDa | 0.021738 |
| ETNK1 | ethanolamine kinase 1 | 0.0216214 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0215425 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0212429 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0212068 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.020954 |
| SET | SET nuclear proto-oncogene | 0.020517 |
| RBM25 | RNA binding motif protein 25 | 0.0204441 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0203041 |
| RPS14 | ribosomal protein S14 | 0.0199159 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0196444 |
| RPL35A | ribosomal protein L35a | 0.019586 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0193712 |
| NEBL | nebulette | 0.019015 |
| ATP5F1A | ATP synthase F1 subunit alpha | 0.0185972 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0184849 |
| TOM1L2 | target of myb1-like 2 (chicken) | 0.0184309 |
| PHF14 | PHD finger protein 14 | 0.0182355 |
| PCBP2 | poly(rC) binding protein 2 | 0.0181134 |
| RPL9 | ribosomal protein L9 | 0.0181102 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0180117 |
| FN1 | fibronectin 1 | 0.0180088 |
| SHLD2 | shieldin complex subunit 2 | 0.0177801 |
| SNX9 | sorting nexin 9 | 0.0174936 |
| ERBIN | erbb2 interacting protein | 0.0174429 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0173648 |
| LSAMP | limbic system-associated membrane protein | 0.0173078 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0172145 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 0.0171074 |
| RPS12 | ribosomal protein S12 | 0.017038 |
| ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 | 0.0169784 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0169548 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.0167157 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0166955 |
| UBE3A | ubiquitin protein ligase E3A | 0.0164666 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0164161 |
| TRIM37 | tripartite motif containing 37 | 0.0159953 |
| NOP56 | NOP56 ribonucleoprotein | 0.0159822 |
| PNN | pinin, desmosome associated protein | 0.0158058 |
| HNRNPLL | heterogeneous nuclear ribonucleoprotein L-like | 0.0156628 |
| ENAH | enabled homolog (Drosophila) | 0.0155881 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | 0.0155522 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0154962 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | 0.0154676 |
| TASOR2 | transcription activation suppressor family member 2 | 0.0153533 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0153143 |
| KIF5C | kinesin family member 5C | 0.0152622 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0152134 |
| CWC27 | CWC27 spliceosome-associated protein homolog (S. cerevisiae) | 0.0152017 |
| MGA | MGA, MAX dimerization protein | 0.0151743 |
| DOCK4 | dedicator of cytokinesis 4 | 0.015094 |
| RPL36A | ribosomal protein L36a | 0.0150886 |
| TPP2 | tripeptidyl peptidase II | 0.0148476 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0148162 |
| NF1 | neurofibromin 1 | 0.0147738 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 | 0.0147734 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0147675 |
| SLK | STE20-like kinase | 0.014764 |
| S100A9 | S100 calcium binding protein A9 | 0.0147447 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0146824 |
| PEG10 | paternally expressed 10 | 0.0146683 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0145284 |
| RFLNA | refilin A | 0.0144786 |
| DIAPH3 | diaphanous-related formin 3 | 0.0144483 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0143725 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) | 0.0143055 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0142954 |
| CCDC88A | coiled-coil domain containing 88A | 0.0142248 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0142161 |
| RNF220 | ring finger protein 220 | 0.0141554 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.01415 |
| ZNF207 | zinc finger protein 207 | 0.0140887 |
| CDC27 | cell division cycle 27 | 0.0140382 |
| HELLS | helicase, lymphoid-specific | 0.0140346 |
| GMPS | guanine monphosphate synthase | 0.0140269 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0139766 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.105679 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0814797 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0741267 |
| ZNF608 | zinc finger protein 608 | -0.0683462 |
| FMNL2 | formin-like 2 | -0.065091 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0614792 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0511188 |
| TENM3 | teneurin transmembrane protein 3 | -0.0503367 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0476206 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0449367 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0443152 |
| RAD51B | RAD51 paralog B | -0.0440782 |
| ATP11A | ATPase, class VI, type 11A | -0.0439449 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0428575 |
| VMP1 | vacuole membrane protein 1 | -0.0422358 |
| FOXO3 | forkhead box O3 | -0.0390095 |
| NGLY1 | N-glycanase 1 | -0.0377215 |
| ACTG1 | actin gamma 1 | -0.0364033 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0358784 |
| CADM2 | cell adhesion molecule 2 | -0.0355737 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0355126 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0339335 |
| TPD52 | tumor protein D52 | -0.0312387 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0312235 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0311626 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.031022 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.0309353 |
| FBXO11 | F-box protein 11 | -0.0308437 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0306063 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0303539 |
| NFIA | nuclear factor I/A | -0.0297869 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0293919 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0292224 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | -0.0289986 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0279366 |
| FOXJ3 | forkhead box J3 | -0.0276527 |
| GNAS | GNAS complex locus | -0.0271513 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0271449 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.027012 |
| ARFGEF3 | ARFGEF family member 3 | -0.0268304 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0268131 |
| CDK19 | cyclin-dependent kinase 19 | -0.0263144 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.0262019 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0260698 |
| GLG1 | golgi glycoprotein 1 | -0.0259095 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0259037 |
| SUN1 | Sad1 and UNC84 domain containing 1 | -0.0257119 |
| APP | amyloid beta (A4) precursor protein | -0.0255364 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | -0.025499 |
| RPL13A | ribosomal protein L13a | -0.0254919 |
| FAM13A | family with sequence similarity 13, member A | -0.025422 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 | -0.025383 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0249163 |
| NXN | nucleoredoxin | -0.0248681 |
| ZNF544 | zinc finger protein 544 | -0.024858 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.02468 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.024552 |
| RIGI | RNA sensor RIG-I | -0.0244481 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0242178 |
| NBEAL1 | neurobeachin-like 1 | -0.0238546 |
| COL5A2 | collagen, type V, alpha 2 | -0.0233136 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | -0.0231697 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0231653 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0231215 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0231011 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0230725 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0230627 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0230294 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0225815 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.022461 |
| HDLBP | high density lipoprotein binding protein | -0.0222922 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0219772 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0219196 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0216293 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.021364 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0213442 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0211845 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0211716 |
| MLIP | muscular LMNA-interacting protein | -0.0211346 |
| DST | dystonin | -0.0210823 |
| ATRN | attractin | -0.0209228 |
| CFDP1 | craniofacial development protein 1 | -0.0206263 |
| CABIN1 | calcineurin binding protein 1 | -0.0206088 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0205526 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0203743 |
| NFIB | nuclear factor I/B | -0.0203591 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0203473 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0203461 |
| RPS20 | ribosomal protein S20 | -0.020329 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.020053 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0198608 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0198564 |
| POU2F1 | POU class 2 homeobox 1 | -0.0198462 |
| RPL27A | ribosomal protein L27a | -0.0197781 |
| ZNF33A | zinc finger protein 33A | -0.0195859 |
| TAOK1 | TAO kinase 1 | -0.0195581 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.019407 |
| ZFHX3 | zinc finger homeobox 3 | -0.0192481 |
| STRBP | spermatid perinuclear RNA binding protein | -0.0191714 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0190452 |