| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benproperine (phosphate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Benproperine (phosphate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | 0.14721 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.120383 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0762061 |
| MMP7 | matrix metallopeptidase 7 | 0.0758023 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0701857 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0630616 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0577792 |
| LAMB3 | laminin, beta 3 | 0.0569523 |
| DTNA | dystrobrevin, alpha | 0.0525848 |
| PLAU | plasminogen activator, urokinase | 0.0478136 |
| PGK1 | phosphoglycerate kinase 1 | 0.0437301 |
| RPL35A | ribosomal protein L35a | 0.042483 |
| HMGA1 | high mobility group AT-hook 1 | 0.0408344 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.03998 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0397902 |
| VIM | vimentin | 0.0388024 |
| S100A6 | S100 calcium binding protein A6 | 0.0374188 |
| ATP13A3 | ATPase type 13A3 | 0.0359097 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0352383 |
| RPL23 | ribosomal protein L23 | 0.0336397 |
| USP3 | ubiquitin specific peptidase 3 | 0.0333865 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0328398 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0319647 |
| ENO1 | enolase 1, (alpha) | 0.0316642 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0308508 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0307269 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0303795 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0299009 |
| NCKAP5 | NCK-associated protein 5 | 0.0275401 |
| AHNAK | AHNAK nucleoprotein | 0.0272869 |
| QKI | QKI, KH domain containing, RNA binding | 0.0267821 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0266431 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0263314 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0257389 |
| HLA-A | major histocompatibility complex, class I, A | 0.0255709 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0251779 |
| NUP58 | nucleoporin 58 | 0.0250836 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.024896 |
| KRT8 | keratin 8, type II | 0.0248708 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0244455 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0238952 |
| RPLP0 | ribosomal protein, large, P0 | 0.0238157 |
| RASAL2 | RAS protein activator like 2 | 0.0237613 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0231468 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0231185 |
| FMNL2 | formin-like 2 | 0.0230952 |
| FAM162A | family with sequence similarity 162, member A | 0.0230808 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0224805 |
| HMGA2 | high mobility group AT-hook 2 | 0.0219277 |
| IER3 | immediate early response 3 | 0.0215067 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | 0.021156 |
| CDK6 | cyclin-dependent kinase 6 | 0.021151 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0200908 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0196724 |
| NRG1 | neuregulin 1 | 0.0189819 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.01873 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.01832 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0178402 |
| SLMAP | sarcolemma associated protein | 0.0175795 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0172763 |
| JUN | jun proto-oncogene | 0.0171429 |
| VCAN | versican | 0.0170811 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0163251 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0159999 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0158451 |
| CP | ceruloplasmin (ferroxidase) | 0.0158273 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0157938 |
| EDN1 | endothelin 1 | 0.0155959 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0150369 |
| PLS3 | plastin 3 | 0.014877 |
| MEF2A | myocyte enhancer factor 2A | 0.0142477 |
| TUBB | tubulin, beta class I | 0.0141097 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.0139908 |
| WDR43 | WD repeat domain 43 | 0.0139683 |
| PRSS23 | protease, serine, 23 | 0.0137903 |
| TMEM123 | transmembrane protein 123 | 0.0137692 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0137669 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0135989 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0135706 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0135608 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0135521 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0135048 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0133751 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | 0.0132398 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0131188 |
| FN1 | fibronectin 1 | 0.0131182 |
| ECT2 | epithelial cell transforming 2 | 0.0130735 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0130307 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.0128212 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0126252 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0125894 |
| RPS25 | ribosomal protein S25 | 0.012579 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0125696 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0124927 |
| S100A10 | S100 calcium binding protein A10 | 0.0124853 |
| RHEB | Ras homolog enriched in brain | 0.0123733 |
| CCND1 | cyclin D1 | 0.0123404 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0122491 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0122338 |
| G0S2 | G0/G1 switch 2 | 0.0121188 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.168536 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.137429 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.133689 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.131254 |
| FNDC3B | fibronectin type III domain containing 3B | -0.128817 |
| SMAD3 | SMAD family member 3 | -0.125903 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.10745 |
| MT2A | metallothionein 2A | -0.106668 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.101547 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0905257 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0874659 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0832541 |
| RPS2 | ribosomal protein S2 | -0.08017 |
| BRD2 | bromodomain containing 2 | -0.0778156 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0750545 |
| APP | amyloid beta (A4) precursor protein | -0.0707905 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.070177 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0665172 |
| APOL1 | apolipoprotein L, 1 | -0.0662159 |
| MT1X | metallothionein 1X | -0.0651424 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0636556 |
| VEGFA | vascular endothelial growth factor A | -0.0631999 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0629086 |
| CDCP1 | CUB domain containing protein 1 | -0.0626174 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.0590526 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0582361 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0575143 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0561739 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0535623 |
| TGM2 | transglutaminase 2 | -0.0524063 |
| TXNIP | thioredoxin interacting protein | -0.0515528 |
| MYO1E | myosin IE | -0.0511196 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0479693 |
| SYNRG | synergin, gamma | -0.0454297 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0452391 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0448416 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0447085 |
| FAM3C | family with sequence similarity 3, member C | -0.0432665 |
| B2M | beta-2-microglobulin | -0.0422732 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0420945 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0412516 |
| ANO6 | anoctamin 6 | -0.0410788 |
| LAMC2 | laminin, gamma 2 | -0.0409422 |
| EFNA5 | ephrin-A5 | -0.0406666 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0406195 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0401462 |
| LAMA4 | laminin, alpha 4 | -0.0401195 |
| CLTC | clathrin, heavy chain (Hc) | -0.0401184 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0396453 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0392927 |
| GOLGB1 | golgin B1 | -0.0391078 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0388212 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0386505 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0375639 |
| NUMB | numb homolog (Drosophila) | -0.0373967 |
| UBC | ubiquitin C | -0.0372532 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0366331 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0360175 |
| RPL19 | ribosomal protein L19 | -0.0354514 |
| PHF3 | PHD finger protein 3 | -0.0352901 |
| FAM13A | family with sequence similarity 13, member A | -0.0346116 |
| TMEM51 | transmembrane protein 51 | -0.0340077 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0339776 |
| USP53 | ubiquitin specific peptidase 53 | -0.0337692 |
| RAP2B | RAP2B, member of RAS oncogene family | -0.0337635 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.033309 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0330415 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0329513 |
| LAMB1 | laminin, beta 1 | -0.0328739 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0328343 |
| SLTM | SAFB-like, transcription modulator | -0.0328119 |
| PFKP | phosphofructokinase, platelet | -0.0325812 |
| TPM3 | tropomyosin 3 | -0.0325712 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0323229 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -0.0322697 |
| CANX | calnexin | -0.0319269 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0309551 |
| NOTCH2 | notch 2 | -0.030949 |
| KIF13B | kinesin family member 13B | -0.0308775 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0304983 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0304169 |
| DSG2 | desmoglein 2 | -0.0303548 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0303184 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0302742 |
| RPL3 | ribosomal protein L3 | -0.0301284 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0299298 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0297403 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0296484 |
| MYOF | myoferlin | -0.029364 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | -0.0291071 |
| ADM | adrenomedullin | -0.0290444 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0287654 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0286278 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0285348 |
| RBM39 | RNA binding motif protein 39 | -0.028334 |
| JMJD1C | jumonji domain containing 1C | -0.0282035 |
| KIAA1217 | KIAA1217 | -0.0280958 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.028015 |
| ARRDC3 | arrestin domain containing 3 | -0.0277679 |
| TMEM165 | transmembrane protein 165 | -0.0275628 |
