| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Benproperine (phosphate) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Benproperine (phosphate)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CCDC146 | coiled-coil domain containing 146 | 0.0171777 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0171246 |
| NPSR1 | neuropeptide S receptor 1 | 0.0162182 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.015706 |
| LMO7 | LIM domain 7 | 0.0142667 |
| SCFD1 | sec1 family domain containing 1 | 0.0133531 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.013042 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0129495 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0128545 |
| FNIP1 | folliculin interacting protein 1 | 0.0127416 |
| SEC24A | SEC24 family member A | 0.0125419 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0125029 |
| SP3 | Sp3 transcription factor | 0.0120439 |
| ADIPOR2 | adiponectin receptor 2 | 0.0119705 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0118949 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 0.0118347 |
| GOLGA2 | golgin A2 | 0.0114795 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0114375 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0113707 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0107856 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0107302 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0106292 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0104129 |
| PLIN2 | perilipin 2 | 0.0103875 |
| COG6 | component of oligomeric golgi complex 6 | 0.0102771 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0102545 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | 0.0101437 |
| CLTC | clathrin, heavy chain (Hc) | 0.0100489 |
| ADAM20 | ADAM metallopeptidase domain 20 | 0.00997324 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.00992216 |
| SLK | STE20-like kinase | 0.0098855 |
| EHBP1 | EH domain binding protein 1 | 0.00982261 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.00976213 |
| FOXB1 | forkhead box B1 | 0.00963852 |
| NEK7 | NIMA-related kinase 7 | 0.00961919 |
| TRIP11 | thyroid hormone receptor interactor 11 | 0.00946988 |
| ZNF432 | zinc finger protein 432 | 0.00943321 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00940551 |
| USP53 | ubiquitin specific peptidase 53 | 0.00938289 |
| FDPS | farnesyl diphosphate synthase | 0.00929722 |
| ZNF395 | zinc finger protein 395 | 0.00921497 |
| CNOT11 | CCR4-NOT transcription complex, subunit 11 | 0.00920912 |
| ANXA1 | annexin A1 | 0.0091718 |
| GOSR1 | golgi SNAP receptor complex member 1 | 0.00905217 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | 0.0089919 |
| COPA | coatomer protein complex, subunit alpha | 0.0089658 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.00890794 |
| CRY1 | cryptochrome circadian clock 1 | 0.00889088 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.00887511 |
| PRPF4B | pre-mRNA processing factor 4B | 0.00886068 |
| MEF2A | myocyte enhancer factor 2A | 0.00882574 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.00882357 |
| RARS2 | arginyl-tRNA synthetase 2, mitochondrial | 0.00878962 |
| A1CF | APOBEC1 complementation factor | 0.00873708 |
| PCED1B | PC-esterase domain containing 1B | 0.00870027 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00868291 |
| DAPK2 | death-associated protein kinase 2 | 0.00866151 |
| FAF2 | Fas associated factor family member 2 | 0.00857661 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.00856052 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.00854054 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.00841681 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.00835012 |
| DIABLO | diablo, IAP-binding mitochondrial protein | 0.00826456 |
| GOLGA3 | golgin A3 | 0.0082161 |
| POF1B | premature ovarian failure, 1B | 0.00802694 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.00802584 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z | 0.00787205 |
| CLMN | calmin (calponin-like, transmembrane) | 0.00783988 |
| TTLL10 | tubulin tyrosine ligase-like family member 10 | 0.00783128 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.00773419 |
| IKZF2 | IKAROS family zinc finger 2 (Helios) | 0.00768933 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00763274 |
| SCARB1 | scavenger receptor class B, member 1 | 0.00762553 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.00757263 |
| TMEM65 | transmembrane protein 65 | 0.00756451 |
| XYLT1 | xylosyltransferase I | 0.00751421 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.00749948 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 0.00749212 |
| TUT7 | terminal uridylyl transferase 7 | 0.00746136 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.00745593 |
| RAB2A | RAB2A, member RAS oncogene family | 0.00743157 |
| NFX1 | nuclear transcription factor, X-box binding 1 | 0.00742069 |
| ACOX1 | acyl-CoA oxidase 1, palmitoyl | 0.0072917 |
| CFAP20DC | CFAP20 domain containing | 0.00723751 |
| RAB22A | RAB22A, member RAS oncogene family | 0.00721039 |
| ZNF33A | zinc finger protein 33A | 0.007197 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.00717189 |
| SRP9 | signal recognition particle 9kDa | 0.00715804 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 | 0.00706048 |
| HBP1 | HMG-box transcription factor 1 | 0.00702604 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 | 0.00699188 |
| RLF | rearranged L-myc fusion | 0.00696134 |
| STK39 | serine threonine kinase 39 | 0.00687483 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.00684858 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.00683667 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.00681215 |
| TMEM87B | transmembrane protein 87B | 0.00680494 |
| AGR2 | anterior gradient 2 | 0.0067986 |
| CLOCK | clock circadian regulator | 0.00667523 |
| ZNF460 | zinc finger protein 460 | 0.00661631 |
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | -0.130665 |
| UBC | ubiquitin C | -0.117541 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.114202 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.112733 |
| LCN2 | lipocalin 2 | -0.0897235 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0803939 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0787036 |
| RNF213 | ring finger protein 213 | -0.0764401 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0756793 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0680503 |
| PKM | pyruvate kinase, muscle | -0.0645929 |
| PTMA | prothymosin, alpha | -0.0638422 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0626813 |
| HLA-B | major histocompatibility complex, class I, B | -0.0605777 |
| ENO1 | enolase 1, (alpha) | -0.0593799 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0576186 |
| STK24 | serine/threonine kinase 24 | -0.0561678 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0551574 |
| RPL23 | ribosomal protein L23 | -0.0548562 |
| RPS6 | ribosomal protein S6 | -0.0546944 |
| PERP | PERP, TP53 apoptosis effector | -0.0542231 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0529161 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0523314 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0487473 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0486934 |
| JUN | jun proto-oncogene | -0.0485149 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0483536 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0464932 |
| TMSB10 | thymosin beta 10 | -0.0461825 |
| RUNX1 | runt-related transcription factor 1 | -0.0458009 |
| AHNAK | AHNAK nucleoprotein | -0.0428479 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0421718 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0413062 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0409628 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0408249 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0408045 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0407476 |
| RPLP1 | ribosomal protein, large, P1 | -0.0402825 |
| MX1 | MX dynamin-like GTPase 1 | -0.0400373 |
| EPCAM | epithelial cell adhesion molecule | -0.0399489 |
| MYO1E | myosin IE | -0.0399144 |
| ACTN4 | actinin, alpha 4 | -0.0389825 |
| RNF43 | ring finger protein 43 | -0.0374092 |
| MX2 | MX dynamin-like GTPase 2 | -0.0361842 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.036093 |
| NCKAP5 | NCK-associated protein 5 | -0.0360836 |
| RPS3 | ribosomal protein S3 | -0.0360213 |
| FAT1 | FAT atypical cadherin 1 | -0.0355329 |
| CALR | calreticulin | -0.0352178 |
| FTL | ferritin, light polypeptide | -0.0349239 |
| RRBP1 | ribosome binding protein 1 | -0.0347369 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0347022 |
| RPS8 | ribosomal protein S8 | -0.0340183 |
| LDHA | lactate dehydrogenase A | -0.0339877 |
| BPTF | bromodomain PHD finger transcription factor | -0.0337965 |
| TXNIP | thioredoxin interacting protein | -0.0333843 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0332944 |
| RPL19 | ribosomal protein L19 | -0.0329746 |
| VMP1 | vacuole membrane protein 1 | -0.0324289 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0321264 |
| SP100 | SP100 nuclear antigen | -0.031846 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0316573 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0315276 |
| RPL35A | ribosomal protein L35a | -0.0314092 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0310858 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0309538 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0302025 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0299292 |
| MT2A | metallothionein 2A | -0.029725 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0293839 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0292392 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0289701 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0288754 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0286751 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0285906 |
| RPL12 | ribosomal protein L12 | -0.0276738 |
| ACTG1 | actin gamma 1 | -0.027601 |
| ADAR | adenosine deaminase, RNA-specific | -0.0275956 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0272466 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0271872 |
| ATXN1 | ataxin 1 | -0.0270385 |
| TMC5 | transmembrane channel-like 5 | -0.0270045 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0269689 |
| TRERF1 | transcriptional regulating factor 1 | -0.0268225 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0263522 |
| RPS27 | ribosomal protein S27 | -0.0261983 |
| PHF3 | PHD finger protein 3 | -0.0256204 |
| S100A10 | S100 calcium binding protein A10 | -0.025495 |
| TMEM62 | transmembrane protein 62 | -0.0252062 |
| SFTPA2 | surfactant protein A2 | -0.025111 |
| RPL37A | ribosomal protein L37a | -0.02493 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.024848 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0247217 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0246907 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0245259 |
| IFNGR1 | interferon gamma receptor 1 | -0.0245187 |
| RPS27A | ribosomal protein S27a | -0.0244187 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0243956 |
| RPLP2 | ribosomal protein, large, P2 | -0.024303 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0242583 |